There has been a steady and continued research effort directed to understanding both the function and the role of mast cells and basophils ever since these cells were first described at the end of the nineteenth century. One of the most significant advances has perhaps been the appreciation of the fact that mast cells do not represent a single homogenous population of cells: they display heterogeneity at the morphological, biochemical and functional levels. The one characteristic that unites all types of mast cells and basophils appears to be the possession of the high affinity membrane receptor for immunoglobulin E, through which the cells may be stimulated. This volume begins with a review of the origin and development of mast cells and basophils. It continues by reviewing our knowledge of the stimuli to mast cells and basophils and the biochemical mechanisms which link the signal generated by stimulus to the response machinery of the cell. Further chapters deal with the drug control of mast cell and basophil responses, the heterogeneity of the cells' functions and the mediators' release by the cells, along with the morphological aspects of the cells' function. This book is completed by a selection of examples which examine the role of the mast cells or basophils in lung, skin and gastrointestinal tract. However, the role of the mast cell with regard to normal physiology, remains an open question. This book aims to provide an up-to-date account of mast cell and basophil biology, together with an insight into the functional relevance of these cells in some tissue types.
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Key Phrases - Statistically Improbable Phrases (SIPs):
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identifiable mast cells, mast cell subpopulations, mast cell colonies, dense concentric membranes, intestinal mast cell response, mucosal mast cell protease, polybasic molecules, mast cell heterogeneity, cutaneous hasophil hypersensitivity, intestinal mucosal mast cells, mast cell subsets, differentiated mast cells, human skin mast cells, cultured mast cells, basic secretagogues, human lung mast cells, mast cell subtypes, degranulation channels, mast cell differentiation, intestinal mast cells, mast cell precursors, disodium cromoglvcate, degranulation chambers, rat serosal mast cells, peritoneal mast cells Key Phrases - Capitalized Phrases (CAPs): (learn more)
Natl Acad, Allergy Clin, Allergy Appl, New York, Academic Press, Cell Biol, Agents Actions, Raven Press, Acta Pathol, Nail Acad, Parasite Immunol, Acta Derm, Dias da Silva, Marcel Dekker, Blood Cell Biochemistry, Boca Raton, Plenum Press, Role of G-Proteins, Ness York, Sites of Interaction, Allergy Immunol, Cell Mol, Control of Exocvtosis, Drug Res, Kluwer Academic Publishers New!
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identifiable mast cells, mast cell subpopulations, mast cell colonies, dense concentric membranes, intestinal mast cell response, mucosal mast cell protease, polybasic molecules, mast cell heterogeneity, cutaneous hasophil hypersensitivity, intestinal mucosal mast cells, mast cell subsets, differentiated mast cells, human skin mast cells, cultured mast cells, basic secretagogues, human lung mast cells, mast cell subtypes, degranulation channels, mast cell differentiation, intestinal mast cells, mast cell precursors, disodium cromoglvcate, degranulation chambers, rat serosal mast cells, peritoneal mast cells Key Phrases - Capitalized Phrases (CAPs): (learn more)
Natl Acad, Allergy Clin, Allergy Appl, New York, Academic Press, Cell Biol, Agents Actions, Raven Press, Acta Pathol, Nail Acad, Parasite Immunol, Acta Derm, Dias da Silva, Marcel Dekker, Blood Cell Biochemistry, Boca Raton, Plenum Press, Role of G-Proteins, Ness York, Sites of Interaction, Allergy Immunol, Cell Mol, Control of Exocvtosis, Drug Res, Kluwer Academic Publishers New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 22
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8
books
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- Mast Cell and Basophil Differentiation and Function in Health and Disease by Stephen J. Galli on 7 pages
- Mast Cell Differentiation and Heterogeneity by A. Dean Befus on 5 pages
- Mast Cells, Mediators and Disease (Immunology and Medicine) by Stephen T. Holgate on page 110, page 135, and page 174
- Human Mast Cells (Advances in Anatomy, Embryology and Cell Biology) by Ann M. Dvorak on page 15, page 89, and page 103
- The Effects of Immune Cells and Inflammation On Smooth Muscle and Enteric Nerves by William J. Snape Jr. on page 110, and page 174
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- Intestinal Mucosa and its Diseases - Pathophysiology and Clinics (Falk Symposium) by W. Domschke on page 490
- Immunopharmacology of the Gastrointestinal System (Handbook of Immunopharmacology) by John M. Wallace in Front Matter
- Beta Agonists in the Treatment of Asthma by John F. Costello on page 48
- International Review of Cytology, Volume 180: A Survey of Cell Biology (International Review of Cell & Molecular Biology) by Kwang W. Jeon on page 218
- Mast Cell Proteases in Immunology and Biology (Clinical Allergy and Immunology) by Caughey on page 304
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