Interpreting Protein Mass Spectra is a hands-on laboratory guide for a wide range of researchers investigating the structures of proteins and peptides. The focus is on the interpretation of structural information gathered through electrospray ionization-mass spectrometry (ESI-MS). The book will also provide useful background and protocols for anyone using matrix-assisted laser desorption/ionization (MALDI), fast atom bombardment (FAB), and secondary ion mass spectrometry (SIMS). The book includes numerous practical examples, detailed discussions of experimental setups, and valuable hints for troubleshooting both methods and the handling of materials.
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Editorial Reviews
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"Mass spectrometry rather than protein mass is the concern of Snyder, a research chemist for the British Army. He explains his chosen methods for interpreting the primary structure of proteins as well as their post-translation modifications. He presents electrospray ionization- mass spectrometry (ESI-MS) as one of the more attractive tools for determining protein integrity and structure, but also outlines the use of high pressure liquid chromatography, capillary electrophoresis, and tandem mass spectrometry. Highlighting phosphoproteins and glycoproteins, he shows how to analyze separate peaks and details within a high mass peak, which give the purity, reproducibility, and signal optimization characteristics of the mass spectrum of a protein. He intends his treatment to be a course text for beginning graduate students and a reference for researchers. It was developed in partnership with the American Chemical Society."--SciTech Book News
"Those wishing to understand and, perhaps, interpret such macromolecular data will be well rewarded by using this as a study guide." -- Doody's
About the Author
Peter Snyder is at U.S. Army Edgewood Chemical Biological Center.
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First Sentence:
Techniques for the transformation of a bulk liquid volume into a very fine mist have had utility for many decades. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
complex glycotype, glucagon trimer, protein mass spectra, residue mass values, mass spectral region, most abundant isotope peak, internal fragment ions, sheep serum albumin, isotope envelope, monoisotopic species, proline effect, recombinant fashion, conventional mass spectrum, average mass values, tandem mass spectrum, fucosylated triantennary, monoisotopic mass, mass spectrometer resolution, isotope species, ion envelope, glycoform distribution, linkage residue, glycan portion, mass spectral peaks, bovine ubiquitin Key Phrases - Capitalized Phrases (CAPs): (learn more)
Academic Press, John Wiley, New York, San Diego, Elsevier Science, American Chemical Society, Mass Spectrom, The Netherlands, Boca Raton, Humana Press, Sara Burgerhartstraat, Rapid Commun, Plenum Press, Mass Spectroin, Allied Topics, Ion Processes, Alass Spectrom, Plenum Publishing Company, Marcel Dekker, Interpreting Protein Mass Spectra, Protein Chemistry, Biological Sciences, Muss Spectrom, Number of Linkage, Afass Spectrom New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Techniques for the transformation of a bulk liquid volume into a very fine mist have had utility for many decades. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
complex glycotype, glucagon trimer, protein mass spectra, residue mass values, mass spectral region, most abundant isotope peak, internal fragment ions, sheep serum albumin, isotope envelope, monoisotopic species, proline effect, recombinant fashion, conventional mass spectrum, average mass values, tandem mass spectrum, fucosylated triantennary, monoisotopic mass, mass spectrometer resolution, isotope species, ion envelope, glycoform distribution, linkage residue, glycan portion, mass spectral peaks, bovine ubiquitin Key Phrases - Capitalized Phrases (CAPs): (learn more)
Academic Press, John Wiley, New York, San Diego, Elsevier Science, American Chemical Society, Mass Spectrom, The Netherlands, Boca Raton, Humana Press, Sara Burgerhartstraat, Rapid Commun, Plenum Press, Mass Spectroin, Allied Topics, Ion Processes, Alass Spectrom, Plenum Publishing Company, Marcel Dekker, Interpreting Protein Mass Spectra, Protein Chemistry, Biological Sciences, Muss Spectrom, Number of Linkage, Afass Spectrom New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 26
books:
See all 26 books this book cites
4
books
cite this book:
- Basic Protein and Peptide Protocols (Methods in Molecular Biology) by John M. Walker on 4 pages
- Mass Spectrometry: Techniques and Applications of Tandem Mass Spectrometry by K. L. Busch on page 13, and Back Matter
- Laboratory Techniques in Biochemistry and Molecular Biology: Sequencing of Proteins and Peptides v. 9 by G. Allen on page 239, and page 240
- Interpretation of Mass Spectra by Fred W. McLafferty in Front Matter, and Back Matter
- Mass Spectrometry Volume 7 (Specialist Periodical Report) by R. A. W. Johnstone on page 240, and Back Matter
See all 26 books this book cites
- Computational Systems Bioinformatics: CSB2006 Conference Proceedings Stanford CA, 14-18 August 2006 (Series on Advances in Bioinformatics and Computational Biology) by Peter Markstein on page 368
- Combinatorial Pattern Matching: 14th Annual Symposium, CPM 2003, Morelia, Michoacán, Mexico, June 25-27, 2003, Proceedings (Lecture Notes in Computer Science) by Ricardo Baeza-Yates on page 277
- Amino Acids, Peptides and Proteins (SPR Amino Acids, Peptides, and Proteins (RSC)) by J. S. Davies in Back Matter
- Mass Spectrometry Basics by Christopher G. Herbert in Back Matter
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