This book is about various aspects of protein folding that is mediated by intramolecular chaperones. Intramolecular chaperones are N-terminal extensions that are usually located between the signal peptide and the mature protein and are essential for the proper function of that protein. Recent research has indicated that these nascent polypeptides are indispensable for proper folding of the proteins they are attached to. Many proteins from both prokaryotic and eukaryotic sources are produced with intramolecular chaperones. This volume gives a summary of the research in this area along with various mechanisms by which this is achieved.
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