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Introduction to Bioinformatics
 
 
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Introduction to Bioinformatics [Paperback]

Teresa Attwood (Author), David Parry-Smith (Author)
3.0 out of 5 stars  See all reviews (1 customer review)

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Book Description

0582327881 978-0582327887 June 9, 2001 1

The book provides an undergraduate (final year) introduction to bioinformatics focussing on two key areas, genomics and protein sequence analysis. It provides an overview of primary, composite and secondary databases, and gives a brief introduction to the Internet and the world wide web.


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Editorial Reviews

From the Back Cover

Bioinformatics, the application of computers in biological sciences and especially analysis of biological sequence data, is becoming an essential tool in molecular biology as genome projects generate vast quantities of data. With new sequences being added to DNA databases, on average, once a minute, there is a pressing need to convert this information into biochemical and biophysical knowledge by deciphering the structural, functional and evolutionary clues encoded in the language of biological sequences.

The unique combination of this timely text and its linked World Wide Web site provide an ideal guide to bioinformatics for newcomers to the field, focusing on two key areas; genomic and protein sequence analysis. The text begins by introducing the most popular databases (protein and nucleic acid), information resources and analysis methods (sequence alignment and pattern recognition) currently available providing the basis for readers to progress to hands-on practical sequence analysis. Chapter 9 then provides a tutorial directly linked to a real application, in the form of an internationally acclaimed interactive bioinformatics practical on the World Wide Web.

The authors aim to encourage a thoughtful approach to sequence analysis and emphasise underlying concepts since, in this rapidly developing area, the specifics will change very quickly.

Features:

  • Unique guide to bioinformatics linked to an interactive practical on the World Wide Web
  • Introduces key databases, tools and resources and outlines pitfalls of methods
  • The Web link provides an excellent opportunity to integrate conventional and Web-based publishing, allowing interactive exploration of concepts discussed in the book

 *Clear two-colour diagrams with full-colour counterparts available on the Web site

*Includes numerous Further Reading suggestions, Web references and a useful Glossary

Dr Teresa K Attwood is a Royal Society University Research fellow and Senior Lecturer in the School of Biological Sciences, University of Manchester, UK, Visiting Fellow at the European Bioinformatics Institute and author and curator of the PRINTS protein fingerprint database.

Dr David J Parry-Smith is Informatics Director at Cambridge Drug Discovery Limited, Cambridge, UK, with main interests in algorithm development

Introduction to Bioinformatics provides an undergraduate (final year) and MSc level introduction to bioinformatics but will be helpful to beginners at all stages, whether in academia or industry.


Product Details

  • Paperback: 240 pages
  • Publisher: Benjamin Cummings; 1 edition (June 9, 2001)
  • Language: English
  • ISBN-10: 0582327881
  • ISBN-13: 978-0582327887
  • Product Dimensions: 9.3 x 6.1 x 0.5 inches
  • Shipping Weight: 13.6 ounces (View shipping rates and policies)
  • Average Customer Review: 3.0 out of 5 stars  See all reviews (1 customer review)
  • Amazon Best Sellers Rank: #1,485,283 in Books (See Top 100 in Books)

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3 of 3 people found the following review helpful:
3.0 out of 5 stars Mediocre (but Chapter 3 is worth reading), December 2, 2003
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This review is from: Introduction to Bioinformatics (Paperback)
Not really worth spending money and time. The price is way too much for a book of this volume. Authors spent too much writing on superficial (length of several paragraphs) introduction to various softwares and databases (e.g., database XXX is produced by YYY research center using ZZZ format, etc.).

Chapter 3 (Protein information resources), however, was worth reading. It presents good figures and tables on various patterns (e.g., pattern, profile, fingerprint, HMM, block) in protein structure.

Also, no errata information is provided from publisher.

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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
protein engineering, structure classification resources, aligned motifs, secondary databases, transferrin family, sequence retrieval system, gapped regions, gap insertion, query sequence, gapped alignments, sequence searching, protein sequence analysis, protein sequence database, primary databases, scoring matrices
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nucleic Acids Research, Sanger Centre, Hidden Markov Models, Feature Table, Twilight Zone, Journal of Molecular Biology, Current Opinion, World Wide Web, Human Genome Project, University College London, Specialist Nodes, European Bioinformatics Institute, Computer Applications, Swiss Institute of Bioinformatics, Rube Goldberg, Virtual Tourist, Structural Biology, Australian National Genomic Information Service, Biochemistry Department, Expressed Sequence Tags
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