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Introduction to the Blood-Brain Barrier: Methodology, Biology and Pathology
 
 
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Introduction to the Blood-Brain Barrier: Methodology, Biology and Pathology [Hardcover]

William M. Pardridge MD (Editor)

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Book Description

0521581249 978-0521581240 August 28, 1998 1
Knowledge of the blood-brain barrier forms an essential component in the understanding of a large proportion of medical disciplines. Nevertheless, ignorance in this field still impedes progress in many areas, including cerebrovascular disease, Alzheimer's disease, cerebral AIDS, brain tumors, and the development of effective new neuropharmaceuticals. This introduction for both researchers and clinicians across the medical sciences is intended to aid both those beginning work directly in this area and those wishing simply to be better informed when interpreting information where the blood-brain barrier may be involved. Recent advances in both methodology and biology are detailed in fifty state-of-the-art chapters written by international authorities.

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Editorial Reviews

Review

"This book, introducing the essential methodologies, biology and pathology of the blood-brain barrier, is welcome, especially when edited by a known expert in the field, William M. Pardridge...recommended reading to those wishing to enter this challenging area of drug delivery" Journal of Controlled Release

Book Description

At the interface between brain and body, knowledge of the blood-brain barrier forms an essential component in the complete understanding of a large proportion of medical disciplines. This introduction for both researchers and clinicians is intended to aid both those beginning work directly in this area and those wishing simply to be better informed when interpreting information where the blood-brain barrier may be involved. Recent advances in both methodology and biology are detailed in 50 state-of-the-art chapters from international authorities.

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Inside This Book (learn more)
First Sentence:
The blood-brain barrier (BBB) is formed by the brain capillary endothelial cell. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
indicator diffusion technique, supraependymal neurons, brain efflux index, situ brain perfusion technique, cerebral microvascular endothelial cells, perfused guinea pig brain, bovine brain capillary endothelial cells, tracer backflux, enhanced pinocytosis, brain microvessel endothelial cells, chicken occludin, isolated brain microvessels, antiluminal membrane, cerebromicrovascular endothelium, cultured brain endothelial cells, indicator diffusion method, isolated brain capillaries, carotid artery perfusion, capillary heterogeneity, endothelial surface charge, human brain endothelial cells, perfused sheep choroid plexus, brain microvascular endothelial cells, abluminal membrane, rat brain endothelial cells
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Brain Res, New York, Acta Neuropathol, Blood Flow Metab, Sanchez del Pino, Raven Press, Cell Biol, Plenum Press, Cancer Res, Acta Physiol, Cell Btol, Blood Flow Aletabol, Evans Blue, Van Renterghem, Academic Press, Brain Pathol, Trypan Blue, Cell Sci, The Netherlands, Acta Neurol, Bill Oldendorf, Nitroblue Tetrazolium, Plenum Publishing Corporation, Cell Res, Cell Tissue Res
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