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An Introduction to Medicinal Chemistry [Paperback]

Graham L. Patrick
4.3 out of 5 stars  See all reviews (9 customer reviews)

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An Introduction to Medicinal Chemistry An Introduction to Medicinal Chemistry 5.0 out of 5 stars (1)
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Book Description

March 25, 2009 0199234477 978-0199234479 4th
The average person in the UK will take more than 14,000 pills over the course of their life, yet few people consider the long road of development that has made that drug work without being toxic. An Introduction to Medicinal Chemistry presents the field in an engaging style that is very accessible to students.

Medicinal chemistry is a fast-moving field whose continuous new developments have far-reaching implications for world health. As such, this text presents a complete course in medicinal chemistry, from first principles of drug action, to design and development, to specific drugs from HIV inhibitors to painkillers.

The book builds on the history of drug development, but does not assume much background knowledge. The focus is on building upon the understandings of the molecular function of drugs, and from there, taking a broad overview of the topical issues and most frequently used techniques.

An Introduction to Medicinal Chemistry remains a leading text for the growing number of medicinal chemistry courses internationally, especially as modules in medical chemistry become a more popular option on chemistry courses. With enhanced attention to the pedagogical details such as key points and boxes, as well as having specific case studies highlighted in distinct sections, Patrick's new edition enables a full understanding of the subject and a clear idea of where the field is heading.

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Editorial Reviews


"Patrick's 3rd edition was a fantastic teaching aid at both BSc, MSc level and for postgraduates in medicinal chemistry. The 4th edition promises to be even better with the addition of en vogue areas of medicinal chemistry including protein-protein interactions and case studies of important blockbuster drugs. A fantastic achievement." John Spencer, University of Greenwich

"Overall organisation is improved over the previous edition, and there is a logical progression from general concepts and history to specific therapeutic areas. There is good coverage of recent developments and the case studies are a very good addition as students find that going through case studies is an effective way of learning the principles of medicinal chemistry" A. Ganesan, University of Southampton

Review from previous edition "Patrick provides a useful and comprehensive introduction to Medicinal Chemistry. It is appropriate for undergraduate level teaching, but also a valuable resource at a more advanced level. The main strength of the book is the breadth of material covered and the accessibility in which the material is presented." Gerd Wagner, University of East Anglia

Review from previous edition "Medicinal Chemistry is excellent-- the best available for undergraduate teaching. Graham is a superb teacher and it shows in the very user-friendly style of the text." Colin Fishwick, University of Leeds

About the Author

Graham Patrick is a lecturer in Organic Chemistry and Medicinal Chemistry at the University of the West of Scotland, Paisley. He is the author of four other undergraduate textbooks covering medicinal chemistry and organic chemistry.

Product Details

  • Paperback: 752 pages
  • Publisher: Oxford University Press; 4th edition (March 25, 2009)
  • Language: English
  • ISBN-10: 0199234477
  • ISBN-13: 978-0199234479
  • Product Dimensions: 7.7 x 1.6 x 10.4 inches
  • Shipping Weight: 3.7 pounds
  • Average Customer Review: 4.3 out of 5 stars  See all reviews (9 customer reviews)
  • Amazon Best Sellers Rank: #549,052 in Books (See Top 100 in Books)

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Customer Reviews

4.3 out of 5 stars
4.3 out of 5 stars
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Most Helpful Customer Reviews
13 of 14 people found the following review helpful
4.0 out of 5 stars A Good Very Basic Look at Medicinal Chemistry January 25, 1999
By A Customer
This book is good in the sense that it is an easy read for anyone interested in the subject. The drawings and cartoons provide a bit of humor to the text and the writing is cloear and focused. The only drawback to the book is that the layperson does not get the full effect of the book without a very good grasp of biochemistry (hence the term layperson!). To get the real scope of the book, one would need to read a good Biochem text ( I personally suggest Lehninger, et. al. Principles of Biochemistry, 3rd ed.). A good pharmacological text would greatly enhance the reader's understanding of the subject as well (i.e. Goodman and Gilman's). Otherwise, the book does give a very brief, very good overview of many aspects of Medicinal Chemistry.
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6 of 6 people found the following review helpful
5.0 out of 5 stars Great Book November 30, 2009
Format:Paperback|Verified Purchase
Bought the third edition for a class and I didnt even need this one but since I read the last edition I knew this would be good as well. So far I have not been disappointed and there is a good deal of information that was not in the last edition. This book is highly recommended.
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1 of 1 people found the following review helpful
5.0 out of 5 stars Outstanding book January 3, 2012
Format:Paperback|Verified Purchase
I have never written a review before but this book has become a fixture in my life. It has become dog eared, marked up, highlighted, underlined - the works. To put this in perspective, I have a background and degree in computer science and am in a PhD program doing computational drug design. I had enough undergrad premed to be dangerous and to follow discussions, but my true strength was on the computational side. I bought this book to help me pick up my chemistry and biochemistry and, with all due humility, it worked like a charm. The explanations are clear and beautiful and, if you like this stuff, it's a page turner. Seriously. Yes, it is an introductory text. But man is it a good one. From here I have been able to move on to other graduate texts, contribute equally in my lab on the biochem front, and even had the opportunity to ask some questions of Christopher Lipinski (of Rule of Five fame) at a conference without embarrassing myself. If you are relatively new to drug design or medicinal chemistry or pharmacology and want to come up to speed quickly, and have at least, say, AP high school chemistry or maybe undergrad chemistry, particularly with at least one organic chem class, BUY THIS BOOK. I cannot say it enough. If you are in a position similar to mine, this book is outstanding. In the context of my degree program, maybe even life changing. The single best academic purchase I've made. Sorry to come off like a fan boy, but this book earned it. It's that good.
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5.0 out of 5 stars Great learning tool February 24, 2013
This book provide a great read understanding the basic foundation to the process of making medicine/drug. I appreciate the amount of effort the author has put into making this textbook enjoyable to read.
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5.0 out of 5 stars Good buy for a medicinal chemistry course. September 30, 2012
By Reuben
Format:Paperback|Verified Purchase
I am glad I bought this book. It is helpful in my understanding of medicinal chemistry. I would recommend this book and amazon service to another student.
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