The process of genetic counseling involves many key components, such as taking a family genetic history, making a diagnosis, and providing communication and support to the family. Among these core processes is the mathematical calculation of the actual risk of a possible genetic disorder. For most physicians and counselors, the mathematics and statistics involved can be major challenge which is not always helped by complex computer programs or lengthy papers full of elaborate formulae. In this clear, reader-friendly guide, Ian Young addresses this problem and demonstrates how risk can be estimated for inherited disorders using a basic knowledge of the laws of probability and their application to clinical problems. The text employs a wealth of clearly explained examples and key points in order to guide the reader to an accurate assessment of the risk of genetic disease. It primarily will appeal to genetic counselors, geneticists, and all those involved in providing medical genetic services. In this new edition, Dr. Young has pruned redundancies and extensively updated the concepts in each of the 10 chapters, and he has included more working examples, a popular feature of the book.
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Editorial Reviews
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`I would recommend this book to any clinicians involved in aspects of genetic counselling' Genetical Research
`Introduction to Risk Calculation in Genetic Counselling more than fulfils its aim to be a "user friendly introduction to risk calculation... for those involved in deliver of genetic counselling services." It is clear in style, with worked examples, and all within 150 pages' BMJ, vol 307
`...this new text is to be welcomed as it is readily accessible to the majority of clinicians and is, in essence, a book that should be on the "working bookshelf"!' Neuromuscular Disorders --This text refers to an alternate Paperback edition.
`Introduction to Risk Calculation in Genetic Counselling more than fulfils its aim to be a "user friendly introduction to risk calculation... for those involved in deliver of genetic counselling services." It is clear in style, with worked examples, and all within 150 pages' BMJ, vol 307
`...this new text is to be welcomed as it is readily accessible to the majority of clinicians and is, in essence, a book that should be on the "working bookshelf"!' Neuromuscular Disorders --This text refers to an alternate Paperback edition.
About the Author
Ian D. Young is a Professor of Pediatric Genetics, Centre for Medical Genetics, City Hospital Nottingham.
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5 of 8 people found the following review helpful:
5.0 out of 5 stars
Excellent,
By Pinaki (India.) - See all my reviews
This review is from: Introduction to Risk Calculation in Genetic Counseling (Paperback)
If to a Genetic Counselor the grammar of medical genetics i.e. risk factor calculation and implication of its outcome means everything then this book belongs to the best group of books. Being a student aspiring to be a genetic counselor, I found this book very informative and useful.Written in a simple way,the complex mathematical calculations have been described with the help of many easy to understand examples. All chapters bear the "key points" which divides the chapter into groups without breaking the continuity.After reading this book an immense idea of Statistical Genetics is bound to emerge in the mind of both students and professionals which will give confidence in the clinic. With best wishes to Ian D.Young for this precise & complete attempt in compiling a good reference book for the genetic counselors.
4 of 7 people found the following review helpful:
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The best!,
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This review is from: Introduction to Risk Calculation in Genetic Counseling (Paperback)
Is difficult to find such a practical book in this field. I think that this book is the best and the only one that can fulfill the clinician and geneticist calculation requirements regarding genetic counseling. It has also a lot of worked examples. Congratulations to the author!
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Inside This Book
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Key Phrases - Statistically Improbable Phrases (SIPs):
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viable imbalance, pachytene diagram, collaborative prenatal study, dominant disorder showing, same autosomal dominant disorder, bowel hyperechogenicity, interchange trisomy, unaffected sons, tertiary trisomy, hyperechogenic bowel, smallest imbalance, germline mosaicism, affected equals, overlapping normal distributions, digenic inheritance, unaffected children, inversion carriers, unaffected brothers, linkage phase, empiric data, mutation ratio, metabolic interference, balanced rearrangement, carrier probability, translocation carriers Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Typed Unaffected Children, Publishing Group, Oxford University Press, Probability Coupling, Conditional Negative, American Journal of Medical Genetics, Ashkenazi Jewish, Human Heredity, John Wiley, Johns Hopkins University Press, Journal of Genetic Counseling New!
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Front Cover | Table of Contents | First Pages | Index | Surprise Me!
viable imbalance, pachytene diagram, collaborative prenatal study, dominant disorder showing, same autosomal dominant disorder, bowel hyperechogenicity, interchange trisomy, unaffected sons, tertiary trisomy, hyperechogenic bowel, smallest imbalance, germline mosaicism, affected equals, overlapping normal distributions, digenic inheritance, unaffected children, inversion carriers, unaffected brothers, linkage phase, empiric data, mutation ratio, metabolic interference, balanced rearrangement, carrier probability, translocation carriers Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Typed Unaffected Children, Publishing Group, Oxford University Press, Probability Coupling, Conditional Negative, American Journal of Medical Genetics, Ashkenazi Jewish, Human Heredity, John Wiley, Johns Hopkins University Press, Journal of Genetic Counseling New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
Citations (learn more)
8
books
cite this book:
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- Practical Genetic Counseling by Peter S. Harper on 4 pages
- Cyber Commerce Reframing by Uwe G. Seebacher on page 181, and Back Matter
- Clinical Cancer Genetics: Risk Counseling and Management by Kenneth Offit on page 239
- A Practical Guide to Human Cancer Genetics by Shirley V. Hodgson in Back Matter
- Gene Therapy: Prospective Technology assessment in its societal context by Jörg Niewöhner on page 121
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