Introduction to In Vitro Cytotoxicology examines in vitro cytotoxicology, which offers new methodologies to toxicity testing. This important new discipline of modern toxicology is gaining increased acceptance as a viable alternative to traditional testing methods. The text discusses the application of in vitro cytotoxicology to toxicity testing and human risk assessment, and it analyzes the advantages and limitations of the tests performed under scientific and regulatory conditions. The book also reviews the optimum utilization of certain tests for specific groups of chemicals relevant to validation programs currently in progress. This book is a useful reference tool for students, researchers, and practitioners interested in academic, industrial, and regulatory toxicology; environmental health; cell biology; pharmacology; dentistry; or human and veterinary medicine.
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Editorial Reviews
Review
This excellent little book truly lives up to its title, and I strongly recommend it as a book that should be in every in vitro toxicology laboratory. Those with experience in the field will be able to say that it will be useful for their new students, but the wiser among them will into it and admit that it provides many new ideas and insights.
Michael Balls, As Quoted in the Journal Alternatives to Laboratory Animals
Volume 22, No. 5, September/October 1994
Michael Balls, As Quoted in the Journal Alternatives to Laboratory Animals
Volume 22, No. 5, September/October 1994
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Inside This Book
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First Sentence:
The techniques to grow animal and human cells and tissues on plastic surfaces or in suspension have contributed significantly to the development of biomedical science. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
human lethal concentrations, organizational toxicity, basal cytotoxicity, basal cell functions, single laboratory validation, vitro cytotoxicology, vitro cytotoxicity testing, cultured lung cells, decision point approach, local irritancy, human fetal lung fibroblasts, vitro toxicity tests, human toxicity data, red uptake assay, enzymatic conditions, continuous cell lines, cell line methods, eye irritancy, ocular irritancy, cellular methods, cell culture methods, cell transformation assays, cytotoxicity tests, toxicokinetic data, multicenter validation Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Cancer Res, Mary Ann Liebert, Academic Press, Cancer Inst, Environmental Protection Agency Gene-Tox Program, Lung Res, Enzymatic Conditions Used, Grand Island, Transformation Assay of Established Cell Lines, Cell Biol, Health Perspect, Continuous Human, John Wiley, Pergamon Press, Telford Press, Food Chem, Handbook of Mutagenicity Test Procedures, Life Sci, Practical Approach, Rabbits Rank, Raven Press, The Basic Science of Poisons, Tissue Cell, Toxicology In Vitro New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
The techniques to grow animal and human cells and tissues on plastic surfaces or in suspension have contributed significantly to the development of biomedical science. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
human lethal concentrations, organizational toxicity, basal cytotoxicity, basal cell functions, single laboratory validation, vitro cytotoxicology, vitro cytotoxicity testing, cultured lung cells, decision point approach, local irritancy, human fetal lung fibroblasts, vitro toxicity tests, human toxicity data, red uptake assay, enzymatic conditions, continuous cell lines, cell line methods, eye irritancy, ocular irritancy, cellular methods, cell culture methods, cell transformation assays, cytotoxicity tests, toxicokinetic data, multicenter validation Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Cancer Res, Mary Ann Liebert, Academic Press, Cancer Inst, Environmental Protection Agency Gene-Tox Program, Lung Res, Enzymatic Conditions Used, Grand Island, Transformation Assay of Established Cell Lines, Cell Biol, Health Perspect, Continuous Human, John Wiley, Pergamon Press, Telford Press, Food Chem, Handbook of Mutagenicity Test Procedures, Life Sci, Practical Approach, Rabbits Rank, Raven Press, The Basic Science of Poisons, Tissue Cell, Toxicology In Vitro New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 20
books:
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- Chemical Mutagens: Principles and Methods for Their Detection by Frederick J. De Serr on 4 pages
- Cellular Systems for Toxicity Testing (Annals of the New York Academy of Sciences) by Gary M. Williams on 4 pages
- Transformation Assay of Established Cell Lines: Mechanisms and Application (I a R C Scientific Publication) by T. Kakunaga on page 166, page 172, and page 173
- Statistics and Experimental Design for Toxicologists, Third Edition by Shayne C. Gad on page 183, page 184, and page 188
- In Vitro Methods in Toxicology by C. K. Atterwill on page 57, and page 105
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