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Ion Channels: Molecules in Action
 
 
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Ion Channels: Molecules in Action [Hardcover]

David J. Aidley (Author), Peter R. Stanfield (Author)
4.0 out of 5 stars  See all reviews (1 customer review)


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Book Description

0521495318 978-0521495318 August 13, 1996 1
Ion channels are crucial components of living cells. Situated in the cell membrane, they allow ions to pass from one side of the membrane to the other. This book provides an overview of ion channel study, including up-to-date coverage of the permeability and selectivity of channels, their gating and modulation, their response to drugs and toxins, and the human diseases that result from channel malfunction. Students of molecular biology, biochemistry, physiology, and neurobiology will benefit from this modern, concise text.

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Editorial Reviews

Review

"...[a] clear and concise introduction to the physics, chemistry, and molecular biology used for ion channel research...what distinguishes this book from standard textbooks is the inclusion of some details of the experimental design, so as to allow the reader to have a better feel of how the studies were done and how the abstract theories emerged from the data...The authors have done a fantastic job in presenting a balanced view and in pointing out unsettled areas." Lily Yeh Jan, Cell

"...this book takes the reader to the frontiers of current research and should be of considerable interest to reproductive and developmental biologists." Ralph B.L. Gwatkin, Molecular Reproduction and Development

"The new Ion Channels book by David J. Aidley and Peter R. Stanfield offers an easy and smooth initiation....The authors have done a fantastic job in presenting a balanced view and in pointing out unsettled areas." Lily Yeh Jan, Cell

Book Description

Ion channels are crucial components of living cells. This overview of ion channel study includes up-to-date coverage of the permeability and selectivity of channels, their gating and modulation, their response to drugs and toxins, and the human diseases that result from channel malfunction.

Product Details

  • Hardcover: 319 pages
  • Publisher: Cambridge University Press; 1 edition (August 13, 1996)
  • Language: English
  • ISBN-10: 0521495318
  • ISBN-13: 978-0521495318
  • Product Dimensions: 10 x 7.7 x 0.8 inches
  • Shipping Weight: 1.9 pounds
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (1 customer review)
  • Amazon Best Sellers Rank: #7,705,531 in Books (See Top 100 in Books)

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4.0 out of 5 stars Excellent introduction, March 15, 2005
By 
Terrell T. Gibbs (Jamaica Plain, MA United States) - See all my reviews
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Getting a bit old now, but although it doesn't cover some of the most recent work it is by no means out of date. It remains one of the best introductions to voltage and ligand-gated ion channels and to electrophysiological methods of study. A good entry to the field, with an excellent bibliography of the primary literature. I don't know if I can recommend it at its list price (it is a slim volume), but used it could be a great buy.
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Inside This Book (learn more)
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First Sentence:
Ion channels are crucial components in the activity of living cells. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
retinal channel, clamped depolarizations, electrodiffusion model, dwell time histograms, nicotinic acetylcholine receptor channel, patch clamp records, voltage clamp system, olfactory channel, single channel records, inward rectifier potassium channels, gating and modulation, gating charge movement, different membrane potentials, permeant ions, pipette electrode, acetylcholine receptor channels, acetylcholine binding site, gating currents, disulphide links, crystal radii, mutant channels, caesium ions, single channel currents, gramicidin channels, rubidium ions
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Macmillan Magazines Limited, Cell Press, The Rockefeller University Press, Kyoto University, Elsevier Trends Journals
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