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Jaagsiekte Sheep Retrovirus and Lung Cancer. Current Topics in Microbiology and Immunology, No. 275
 
 
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Jaagsiekte Sheep Retrovirus and Lung Cancer. Current Topics in Microbiology and Immunology, No. 275 [Hardcover]

Hung Y. Fan (Editor)

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Book Description

January 31, 2003 3540440968 978-3540440963 1
Retroviruses have been of great importance to biomedical science for the past half century. Initially, studies on oncogenic animal retroviruses provided important insights into molecular processes in carcinogenesis – most notably the existence and mechanisms of action of oncogenes and proto-oncogenes. Moreover, several human diseases are caused by retroviruses, including AIDS, adult T-cell leukemia and the neurological disease HAM/TSP. The topic of this volume is a relatively unknown animal retrovirus, jaagsiekte sheep retrovirus, the causative agent of transmissible lung cancer in sheep –ovine pulmonary adenocarcinoma. The disease was first documented in South Africa in the 1800s, it has a wide geographical distribution, and it is of economic importance in high endemic regions. However, until very recently the nature of the etiologic agent was unclear, and relatively few laboratories actively studied the disease.

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Inside This Book (learn more)
First Sentence:
One of the first documented reports of ovine pulmonary adenocarcinoma (OPA) is a letter written by a farmer in 1825 who complained to the magistrate in the Cape of Good Hope in South Africa that he was losing many of his sheep to a disease he called Jaagziekte, a Dutch word that was translated into Afrikaans as as Jaagsiekte. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
ovine pulmonary adenocarcinoma, contagious lung cancer, human bronchioloalveolar carcinoma, jaagsiekte retrovirus, sheep pulmonary adenomatosis, enzootic nasal tumour, ovine pulmonary carcinoma, jaagsiekte sheep retrovirus, mixed adenocarcinoma, tumour extracts, nasal adenocarcinoma, sheep genome, acinar adenocarcinoma, exogenous virus, tumour nodules, exogenous form, endogenous loci, env proteins, endogenous sequences, nasal fluid, affected sheep, clara cells, vector transduction, lung fluid, lung sections
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Proc Natl Acad Sci, Journal of Virology, South Africa, Cold Spring Harbor, Vet Res, New York, Slow Viruses, Biol Chem, Journal of the National Cancer Institute, College of Veterinary Medicine, Natl Cancer Inst, Vet Microbiol, Journal of Comparative Pathology, Mol Cell Biol, University of Georgia, Veterinary Record, Bush Loan, Kluwer Academic Publishers, Onderstepoort Journal of Veterinary Research, Pentlands Science Park, Universidad de Zaragoza, Vet Immunol Immunopathol, Vet Rec, Virus Res, World Health Organization
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