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  • Jarrow Formulas Pterostilbene, 50 Mg, 60 Veggie Caps
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Jarrow Formulas Pterostilbene, 50 Mg, 60 Veggie Caps

from Jarrow
146 customer reviews

Price: $12.75 ($0.21 / Count) & FREE Shipping on orders over $35. Details
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60
  • Sirtuin activator
  • Calorie restriction mimetic
  • Cardiovascular and neurologic health

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Frequently Bought Together

Jarrow Formulas Pterostilbene, 50 Mg, 60 Veggie Caps + N (R) Niagen Nicotinamide Riboside - 60 capsules
Price for both: $58.47

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Product Description

Size:60

Product Profile

Pterostilbene (terro-STILL-bean) is found naturally in blueberries, grapes, and in the bark of the Indian Kino Tree (Pterocarpus marsupium). The name Pterocarpus derives from ancient Greek and means “wing fruit”, referring to the shape of the seedpods in this genus. Preparations of the Indian Kino Tree have been used in Ayurvedic medicine for centuries in relation to inflammation and blood-sugar balance. Similarly, resveratrol, a structural cousin of pterostilbene, has been touted for effects related to the heart.*

Pterostilbene vs. Resveratrol

Pterostilbene has been shown to have the same antioxidant potential as resveratrol in a standard assay of antioxidant potential (Trolox). However, the two methylated hydroxyl groups make pterostilbene more lipophilic and less susceptible to conjugation-induced degradation; this leads to a greater half-life in the body compared to resveratrol (105 vs. 14 minutes). These specific structural differences seem to make resveratrol more adept at combating reactive oxygen species (ROS) in whole blood and lymphocytes and pterostilbene better at targeting extracellelular ROS.* Such extracellular ROS are often responsible for tissue damage with imbalanced inflammatory response, amongst other things. As such, pterostilbene and resveratrol tend to be more complementary in their action than competitive. Work in animals has even suggested synergies between the two, along with quercetin. This is one reason both are included, along with quercetin and other components found in grapes, in a related Jarrow Formulas product: Resveratrol Synergy.

Distinguishing Features:

  • Made with pTeroPure pterostilbene
  • 99% pure dimethylresveratrol
  • 50 mg pterostilbene per serving
Matters Of The Heart*

Reduced oxidative stress and a properly modulated inflammatory response seem to be at the root of enduring health, particularly cardiovascular health. In vitro and animal studies suggest pterostilbene has positive effects on multiple inflammation-related biomarkers.* But as we know, a healthy heart and network of blood vessels also involves balanced levels of blood lipids and blood sugar. It’s understood that chronically high plasma levels of glucose lead to advanced glycation end products (AGE), which in turn cause the deterioration of bodily tissues, and an increased risk of developing insulin resistance. Pterostilbene seems to offer some protection from AGEs and may offer defense against metabolic change associated with elevated blood sugar.* When it comes to blood-lipids, pterostilbene has been found to activate peroxisome proliferator-activated receptor alpha (PPARa). PPARa is involved with blood-lipid regulation, synthesis, and metabolism; in vitro and animal studies suggest that through this interaction pterostilbene can have positive effects on blood-lipids.*

Tip-Top Brain Health*

Emerging research suggests that pterostilbene may have something to offer brains too. For instance, pterostilbene may help to defend against a decrease in release of the neurotransmitter dopamine following exposure to an oxidative stressor (hydrogen peroxide).* In rats, pterostilbene leads to a decrease in the distance traveled and a decrease in the time to get to a platform between two trials in the Morris water maze test (i. e. suggesting memory support).* How this may work remains an open question, but it is known that PPARa agonists, like pterostilbene, confer a protective effect on cortical areas of the brain, like the hippocampus.* So it’s possible a similar mechanism could be at the root of both brain and cardiovascular effects.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


Product Details

Size: 60
  • Product Dimensions: 1.8 x 1.8 x 3.2 inches ; 1 ounces
  • Shipping Weight: 1.6 ounces (View shipping rates and policies)
  • Domestic Shipping: Currently, item can be shipped only within the U.S. and to APO/FPO addresses. For APO/FPO shipments, please check with the manufacturer regarding warranty and support issues.
  • International Shipping: This item is not eligible for international shipping. Learn More
  • Origin: USA
  • ASIN: B005ACNW5S
  • UPC: 790011200406
  • Item model number: PTERO
  • Average Customer Review: 4.4 out of 5 stars  See all reviews (146 customer reviews)
  • Amazon Best Sellers Rank: #10,123 in Health & Personal Care (See Top 100 in Health & Personal Care)
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Important Information

Ingredients
Cellulose, magnesium stearate (vegetable source) and silicon dioxide. Capsule consists of hydroxyproplymethylcellulose.

Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. Please see our full disclaimer below.

Customer Questions & Answers

Customer Reviews

Most Helpful Customer Reviews

37 of 40 people found the following review helpful By Joe MacBu on June 23, 2013
Size: 60 Vine Customer Review of Free Product ( What's this? )
Pterostilbene is the primary antioxidant found in blueberries, and numerous studies (in animal models) have demonstrated that it may be effective in fighting cancer, inflammation, diabetes, vascular disease and neurological disease. It is similar to resveratrol (found in red wine), but has about 4x better bioavailability. Based on the evidence we have so far, it really does seem like an incredibly powerful antioxidant that works on multiple pathways that are critical to disease states, in multiple organ systems. Unfortunately, most of the studies hitherto have been performed on animals, and there is still much to learn about its effects on humans. So far, it seems that taking 100mg per day is well-tolerated without any adverse effects.

If you're interested in knowing more about how pterostilbene probably works, you should read this detailed scientific review article:
"A Review of Pterostilbene Antioxidant Activity and Disease Modification" by Denise McCormack and David McFadden. You can find it via a search on PubMed.

I do have an issue with Jarrows claiming that pterostilbene is a sirtuin activator. I can find only 1 peer-reviewed publication that mentions pterostilbene and sirtuin, and it states that sirtuin was not activated (or increased) by pterostilbene. See reference below.

-----------------

Neurobiol Aging. 2012 Sep;33(9):2062-71. doi: 10.1016/j.neurobiolaging.2011.08.015. Epub 2011 Oct 7.
Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease.
Chang J, Rimando A, Pallas M, Camins A, Porquet D, Reeves J, Shukitt-Hale B, Smith MA, Joseph JA, Casadesus G.
Department of Neuroscience, Case Western Reserve University, Cleveland, OH 44106, USA.
Read more ›
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39 of 45 people found the following review helpful By David Bennett VINE VOICE on January 3, 2013
Size: 60 Vine Customer Review of Free Product ( What's this? )
I have taken Resveratrol since 2008, and was interested when I started reading about Pterostilbene.

Pterostilbene is a chemical in grapes and blueberries that is very similar to Resveratrol. Unfortunately, Resveratrol is known to be fairly poorly absorbed. Fortunately, research suggests Pterostilbene has similar benefits, is better absorbed than Resveratrol, and also stays in the body longer. Animal studies seem very encouraging for a variety of health conditions, such as heart disease and diabetes.

A Resveratrol supplement is usually just Japanese Knotweed extract, whereas this extract seems white and more chemically pure. I split my doses of Resveratrol up, which involves consuming powder in the capsule, and I don't care for the taste of Knotweed powder. Pterostilbene just tastes like nothing, which makes splitting the dose easier. The capsules are very very tiny, and easy to take.

Two possible drawbacks of this supplement are the price and its newness. The price is high relative to plain-old Resveratrol. Maybe, like Resveratrol, the price will fall as it becomes more popular and available. Second, human safety studies and appropriate dosage information are limited. Granted, we consume Pterostilbene naturally in many fruits, but I always like to err on the side of safety. I am currently taking a capsule a week, and sticking to Resveratrol the other days, until I become comfortable with its long-term safety.

Overall, this is a promising supplement that could eclipse Resveratrol in its anti-aging power. It is impossible to notice any immediate benefits, but the hope is that it is protecting me long-term inside my body. Time will tell I guess!
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21 of 23 people found the following review helpful By R. Brissette on September 1, 2014
Size: 60
While reading about promising aspects of this supplement, I came upon one and only reliable study on humans and lipid profiles (double blind etc). Study (university of Mississippi) was apparently sponsored by a manufacturer, hoping for good results based on animal study results.... well, with humans did not work so well... very modest blood pressure benefits, while Lipid profile results must have been very disappointing...about 20 points up in LDL alone...and manor, albeit signification drop in HDL (like 5 units). To leave this out of a description and actually quote now outdated animal study's when we have a quality human study seems unconscionable. 20 points in LDL is major raise... (15% or so increase for average person) and would seems as a major reason not to take it....
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9 of 9 people found the following review helpful By DavBost on March 1, 2015
Size: 60 Verified Purchase
I have not written a review for a supplement before, and I am writing this after only having had this product for 24 hours. I have been waking with numb and/or tingling arms and hands after sleeping in positions with bent elbows etc. These positions are not new, so I started to wonder if my circulation was going south in my mid 60s. I have also been feeling mildly sluggish as well. Some products for circulation have resulted in erratic pulse and/or rise in blood pressure with a nervous type energy. So I though I would give this a try. It arrived at noon yesterday and I took one immediately, and within two hours I felt lighter and buoyant energetically and also more focused mentally. I took another at bed time, and woke this morning with no tingling or numbness. Amazing after less than 24 hours taking this. I took another this morning and had greater than usual energy at the gym and my mood was just wonderful. I have taken my blood pressure a few times and it is normal with no spikes. I can't say this would be the same for everyone, and some here say they have noticed no change. I only speak from my own short 24 hour experience, but it is very real and I feel just great. I look forward to the long term results.
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Jarrow Formulas Pterostilbene, 50 Mg, 60 Veggie Caps
This item: Jarrow Formulas Pterostilbene, 50 Mg, 60 Veggie Caps
Price: $12.75
Ships from and sold by Amazon.com
Want to discover more products? Check out these pages to see more: blueberry capsules, vitacost pterostilbene

Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Amazon.com assumes no liability for inaccuracies or misstatements about products.