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Latency Strategies of Herpesviruses
 
 
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Latency Strategies of Herpesviruses [Hardcover]

Janos Minarovits (Editor), Eva Gonczol (Editor), Tibor Valyi-Nagy (Editor)

Price: $139.00 & this item ships for FREE with Super Saver Shipping. Details
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Book Description

October 12, 2006

This volume provides an overview of the latency strategies developed during the estimated 200,000 year-long coevolution of Alpha-, Beta- and Gammaherpesvirinae and their host species. While the main emphasis is on herpesviruses infecting humans, relevant cases if herpesviruses infecting animals are covered as well.

Special emphasis is given to results on molecular mechanisms regulating latent promoters of herpesvirus genomes and signals and molecular pathways resulting in reactivation of latent viral genomes.


Editorial Reviews

From the Back Cover

Latency is a fascinating property of herpesviruses which ensures the maintenance of their genetic information in their hosts for an extended period in the absence of productive virus replication. Focusing on human herpesviruses and animal models of herpesvirus-associated human diseases, this is the first book dealing with the intricate epigenetic mechanisms (DNA methylation, histone modification, alteration of chromatin structure) that regulate latency-associated transcription. Special attention is given to immune evasion "tricks" blocking immune responses to herpesvirus infected cells and viral RNAs and proteins involved in malignant transformation. Latency Strategies of Herpesviruses is an ideal book for researchers, scientists and graduate students in the fields of virology, immunology, microbiology, bacteriology, and veterinary medicine.


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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
splenic latency, latency strategies, murid herpesvirus, lytic virus replication, productive virus replication, murine gammaherpesvirus, lytic reactivation, chromosomal matrix, viral episome, lytic gene expression, human ganglia, latency promoters, murine herpesvirus, equine herpesviruses, infectious virus production, simplex virus latency, human trigeminal ganglia, reactivation from latency, latency type, latent nuclear antigen, episomal maintenance, maintaining latency, lytic replication, plex virus type, infected neurons
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Latency Strategies of Alphaherpesviruses, Cytomegalovirus Latency, Herpes Simplex Viruses, New World, Old World, Color Plates
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