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Longevity, Senescence, and the Genome (The John D. and Catherine T. MacArthur Foundation Series on Mental Health and De)
 
 
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Longevity, Senescence, and the Genome (The John D. and Catherine T. MacArthur Foundation Series on Mental Health and De) [Paperback]

Caleb E. Finch (Author)

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Book Description

May 16, 1994 0226248895 978-0226248899
Featuring extensive references, updated for this paperback edition, Longevity, Senescence, and the Genome constitutes a landmark contribution to biomedicine and the evolutionary biology of aging.

To enhance gerontology's focus on human age-related dysfunctions, Caleb E. Finch provides a comparative review of all the phyla of organisms, broadening gerontology to intersect with behavioral, developmental, evolutionary, and molecular biology. By comparing species that have different developmental and life spans, Finch proposes an original typology of senescence from rapid to gradual to negligible, and he provides the first multiphyletic calculations of mortality rate constants.

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Inside This Book (learn more)
First Sentence:
This analysis of how the genome influences lifespan and senescence in higher organisms is based on species comparisons across many levels of biological organization. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
mechanical senescence, organismic senescence, mortality schedule data, clonai senescence, senescing species, novo oogenesis, obligate semelparity, genomic totipotency, organismic lifespan, senescent flies, reproductive scheduling, mortality rate coefficients, ovarian oocyte loss, postmaturational changes, short adult phases, transformational genetics, novo gametogenesis, postnatal lifespan, gradual senescence, indeterminate lifespans, oocyte stocks, postmitotic status, limited oogenesis, somatic cell proliferation, statistical lifespan
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Jackson Laboratory, The Comparative Biology of Senescence Fig, North America, Maynard Smith, United States, New Zealand, David Harrison, Framingham Study, Thomas Johnson, Lake Superior, Upper Cretaceous, Upper Devonian, Van Heukelem, World War, Baltimore Longitudinal Study, Bunny Lake, Pacific Salmo, Upper Carboniferous, Frequency of Colonies, Robert Behnke, San Antonio, The Biomarker Problem, Atlantic Salmo, British Columbia, Control Control
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