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Lorenzo's Oil

174 customer reviews

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$10.12 & FREE Shipping on orders over $35. Details Only 20 left in stock (more on the way). Ships from and sold by Gift-wrap available.

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Editorial Reviews

Oscar nominee Nick Nolte and Academy Award winner Susan Sarandon star in this powerful and unforgettable drama based on a true story.For Augusto and Michaela Odone (Nolte and Sarandon), the news that their five-year-old son, Lorenzo, has a rare terminal disease is sobering, to learn there is no known cure is devastating. Despite the prognosis, the Odones embark on an extraordinary mission of love, consulting and sometimes colliding with the world's top doctors and scientists in the quest to save their son. Their relentless struggle tests their marriage, their beliefs and the boundaries of conventional medicine in this critically acclaimed hit from director George Miller (The Witches of Eastwick).

Special Features

  • Theatrical Trailer

  • Product Details

    • Actors: Nick Nolte, Susan Sarandon, Peter Ustinov, Kathleen Wilhoite, Gerry Bamman
    • Directors: George Miller
    • Writers: George Miller, Nick Enright
    • Producers: George Miller, Doug Mitchell
    • Format: Multiple Formats, Color, NTSC
    • Language: English (Dolby Digital 2.0)
    • Subtitles: French, Spanish
    • Subtitles for the Hearing Impaired: English
    • Region: Region 1 (U.S. and Canada only. Read more about DVD formats.)
    • Aspect Ratio: 1.85:1
    • Number of discs: 1
    • Rated: PG-13 (Parental Guidance Suggested)
    • Studio: Universal Studios
    • DVD Release Date: June 1, 2010
    • Run Time: 136 minutes
    • Average Customer Review: 4.6 out of 5 stars  See all reviews (174 customer reviews)
    • ASIN: B0001CNRAM
    • Amazon Best Sellers Rank: #9,864 in Movies & TV (See Top 100 in Movies & TV)
    • Learn more about "Lorenzo's Oil" on IMDb

    Customer Reviews

    Most Helpful Customer Reviews

    96 of 97 people found the following review helpful By Lawyeraau HALL OF FAMETOP 500 REVIEWERVINE VOICE on April 7, 2002
    Format: VHS Tape
    This is the true life story of the Odone family, Augusto, Michaela, and Lorenzo, and their battle with Adrenoleukodystrophy (ALD), a disease that attacks the central nervous system by systemically destroying its protective cover, the myelin sheath. It is an extremely rare disease that is transmitted exclusively to males through a gene that is carried by the mother.
    Augusto, an economist, and Michaela, a linguist, were a well educated, well to do, multi-lingual couple with a little son named Lorenzo who was precocious beyond his years. He spoke English and Italian fluently, as well as the language spoken in the community in Africa in which he spent his very early years. When he returned to the United States at about the age of five, his behavior started to change He came overly aggressive and given to emotional outbursts. After much angst on the part of the Odones over what could be wrong, they were finally told that their son suffered from ALD, which was the functional equivalent of having their son being given a death sentence, as there was no cure for this degenerative disease.
    This well educated couple refused to accept the death sentence meted out to their son by the medical establishment. With no medical background, they disregarded conventional medical wisdom and went about trying to find a cure for their son, in a quest so remarkable and so moving, as to inspire absolute awe in the viewer. A more caring or loving set of parents would be hard to find. Lorenzo is surely loved. Together, Augusto and Michaela take on the medical establishment. What they ended up discovering rocked the medical world. To find out just what it was that they specifically did, you will just have to watch the movie.
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    37 of 38 people found the following review helpful By K. K. Sommer on July 20, 2004
    Format: DVD
    On 07/20/04, I visited the web site [...] and clicked on ABOUT LORENZO & HIS PARENTS where I obtained the following excerpt:

    "About Lorenzo, his Parents, and Oumouri

    (in answer to the many questions we receive)

    Lorenzo celebrated his 25th birthday on May 29, 2003. He is deprived of most of his functions, but his mind is still there. Lorenzo communicates through blinking his eyelids to say no and wiggling his fingers to say yes. He enjoys music and being read to. Lorenzo will not regain his speech or full mobility until we are successful with remyelination.

    Michaela succumbed to cancer in June 2000. Augusto, who continues the fight for his son, works out of his office at Myelin Project Headquarters located in Dunn Loring, Virginia, just outside of Washington D.C.

    Lorenzo likes to receive mail from his ?friends? and well-wishers. You may write to him c/o The Myelin Project, 2136 Gallows Road, Suite E, Dunn Loring, Virginia 22027."

    I encourage you to visit this web site where you can get an update on The Myelin Project, make a donation to

    The Myelin Project, read a letter from Augusto Odone dated 02/19/04, and see pictures of Lorenzo, his Parents, and Oumouri.
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    39 of 42 people found the following review helpful By Geekier than thou TOP 1000 REVIEWERVINE VOICE on July 25, 2000
    Format: VHS Tape
    This is one of those films that sticks with you... there are scenes and overall themes I will NEVER forget. The real life Odone family, portrayed masterfully by Nick Nolte and Susan Surandon, is far beyond what anyone would refer to as inspiring.

    The Odones are a professional power couple. Augusto (Nolte) has adult children from a previous marriage. He and his wife have one child together, young Lorenzo.

    Lorenzo had the benefit of being raised by highly intellectual and caring, multi-lingual parents. Since Augusto Odone is a financial wizard for the World Bank, which provides not only a comfortable, but worldly life for the family now small family. Lorenzo grows up in Africa, speaking English and Italian fluently and being fully conversant in the language spoken by his classmates in Africa.

    When Lorenzo reaches school age, his parents return to the United States and Lorenzo starts school. Suddenly, a child who has grown up fearless and extroverted with others of all ages and cultures is having emotional outbursts in class and getting into fights.

    After it becomes clear that there is a physical reason behind his behavior, not an emotional one, his parents take him to every doctor they can find until they hear that their child has the medical equivalent of a death sentence.

    As a financial expert and a linguist, the medically ignorant Odones are faced with a a problem they don't see a solution for. Their child has a rare disease, so rare, it is financially prohibitive for pharmaceutical companies to invest millions and perhaps even billions on developing a cure. The disease, adrenoleukodystrophy, also known as ALD, is inherited by males from their mothers.
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    11 of 11 people found the following review helpful By Daniel S. Russell on June 5, 2004
    Format: VHS Tape
    Real-life dramas always hold more weight with me, especially when they are crafted as well as "Lorenzo's Oil." The acting is superb and the drama unfolds very carefully and deliberately. I was immediately drawn in. Having known families torn apart by the illness of a child, for me this film captures the paralyzing grief and sense of helplessness that paralyzes a household, and yet this film gives hope when the family starts to fight back against the disease.
    Like Augusto did encountering the disease, I discovered I had learned a great deal just watching the film. I wish more films could be as educational and entertaining at the same time -- a rare breed indeed!
    If you haven't shed at least a few tears by the end of the film, I'm worried about you if you can get tear-free through the closing montage of boys who are alive and well because of Lorenzo's Oil. Everytime I see that part, I cry.
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