Lsd [Paperback]

Otto Snow (Author)

Book Description

ISBN-10: 0966312848 | ISBN-13: 978-0966312843 | Publication Date: November 2003

At age 15, Otto developed hemi-paraesthesic migraine headaches. These cluster migraines resemble a stroke. He was given narcotics, barbiturates and ergot alkaloids. The drugs were making him ill. He learned of a new medication that might help. The drug was LSD-25 and it worked.

His physicians would not prescribe LSD so Otto entered the world of LSD. Several laboratories provided him and other patients with the medication. Included are comments and research from the greatest scientists of the twentieth century. Personal satori experiences. At nineteen, Otto discontinued his exploration of LSD.

LSD is the most comprehensive book ever written on the synthesis of LSD. Otto includes the reactions and the chemistry behind the reactions. Many simplified reactions (e.g. diethylamine from vodka, lysergic acid directly from Claviceps sugar culture, coupling agents from scratch). Extractions translated to English.

LSD is written by someone who has been there and knows the subject/chemistry first hand. LSD is as popular today as it was in the 1970s and 1960s. For many it is a party drug, for others it is a medication. The Decade of the Brain heralded in a new interest in psychedelics and their medical application.

The book is illustrated by Tulasne, Chase, Gill and others. LSD is packed with chemistry for future generations of neurochemists and explorers. 275+ references. UV laminated.

Editorial Reviews

Review

It is a thing of Beauty! -- Dr. Alexander & Ann Shulgin, March 6, 2004

Otto's books are read across the world by amateur and professional chemists, industry, attorneys, and forensic laboratories, including the DEA. -- Thomas Lyttle, Heads Magazine, Vol. 4, Issue 3

From the Publisher

Book Includes: My Introduction to LSD-25
Medical Uses of LSD
Reported Dosages
Treatment of Alcoholics
In the Treatment of PTSD?
In the Treatment of Neuroses
In the Treatment of Migraines
In the Treatment of Schizophrenia?
Therapist (Guide) Must Take Drug
The Environments (Settings)
Sessions in The Yellow Room
Sessions in State Parks
Sessions in Amusement Parks
Religious Experience
Opening of the Mandala (100ug.)
Control of the Mandala
The Ritual of the Million Faces
Niacin (NADH-dependent enzyme)
Satori (17) Temple of The All
Termination of Psychosis
Warning
Water Spirit (100 ug)
LSD is Love
Strobe Candles and the Beads of Lights
Moratorium on LSD-25
Narcotics and Drug Abuse
Dangerous Drugs
The Hallucinogens
Mind-Altering Substances
Weighing Risks
Proposals for Dangerous Drug Legislation
Recommendations Dealing With State Law
Possession for Household or Animal Use
Unauthorized Manufacture
! In Response to Moratorium
Statistics and Anomalies
LSD Laboratories
List I Chemical; Threshold base weight
Investigating LSD Sample
Profile of Laboratory Chemist
Lysergamides
d-Lysergic Acid Diethylamide (LSD-25)
1-Alkyl & N-6 Substituted d-Lysergamides
Hydroxy Substituted d-Lysergamides
Ergotamine Tartrate
Physical Constants; Safety Precautions

The Curtis Reaction:
Lysergic Acid Hydrazine, Lysergic Acid Azide and Lysergic Acid Amides
Racemic Lysergic Acid Hydrazide Using Hydrazine Hydrate and Ergot Alkaloids
Lysergic Acid Azides and Amides from Lysergic Acid Hydrazides
Racemic Lysergic Acid Ethanolamide
Racemic Lysergic Acid Dimethylamide
d-iso-Lysergic Acid-hydroxybutylamide-2
Diethylamide of d-Lysergic Acid
Preparation of d-Lysergic Acid Azide
iso-Lysergic Acid Piperidide
Preparation of d-Lysergic Acid Hydrazides (the New Process)
Lysergic Acid-(3'-allyloxy-2'-oxy-propyl)amide

The Garbrecht Synthesis
Preparation of Amides of Lysergic Acid
Preparation of Ergonovine
Preparation of d-Lysergic Acid Morpholide
Preparation of d-Lysergic Acid Diethylamide
Preparation of Ergonovine
Sulfan B (gamma Sulfuric Acid Anhydride) Preparation
Lysergic Acid Amide Derivative Preparation
1-Methyl-d-Lysergic Acid (+) Butanolamide-(2)
1-Methyl-d-Lysergic Acid Ethylamide
1-n-Propyl-D-lysergic acid (+) Butanolamide-(2)

Alternative Syntheses of Lysergamides

Fractional Crystallization of Lysergamides
Fractional Crystallization of d-Lysergic Acid-hydroxybutylamide-2
Optically Active Salts of Lysergic and iso-Lysergic Acids
Fractional Crystallization of d-Lysergic Acid
Diethylamide d-Tartrate from Racemic Lysergic Acid Diethylamide
Separating and Purifying Alkaloids of Ergot
Crystallization of d-Lysergic Acid Diethylamide Tartrate
Fractional Crystallization of d-Lysergic Acid Piperidide d-Tartrate
Fractional Crystallization of d-Lysergic Acid Cyclobutylamide

Chromotography of Ergot Alkaloids
Separation of Pure Crystallized Ergot Alkaloids
Separation of a Mixture of Ergotamin and Ergotaminin
Pure Ergotamin from a Raw Extract
Separation of Diethylamide of d-Lysergic Acid
Isolation of the Alkaloids from Culture of Ergot (Claviceps purpurea [Fr] Tul.)
Chromatography of Lysergic Acid Diethylamide
Chromatography of d-Lysergic Acid Piperidide
Chromatography of Amides of Lysergic Acid
Chromatography of Lysergic Acid Morpholide
Chromatography of d-Lysergic Acid N-methyl-N-isopropylamide

Isomerization of Lysergamides
Isomerization of d-iso-Lysergic Acid-Hydroxybutylamide-2
Isomerization of d-iso-Lysergic Acid Cyclopropylamide
Epimerization of d-iso-LSD into d-LSD
Free Base Ergot Alkaloids from Their Salts (ergobasine)

Lysergic Acid
Lysergic Acid from Ergot Alkaloids
Preparation of Lysergic Acid
Recrystallization of Lysergic Acid
Lysergic Acid from 6-Methyl-delta-8,9-ergolene-8-carboxylic Acid

Ergot Alkaloids and Ergolines
Ergoline Alkaloids fromConvolulaceae
Rivea corymobosa
Morning Glories
Argyreia nervosa
Extraction of Ergoline Alkaloids From Seeds

Method of Developing Claviceps purpurea
Field Inoculation with Claviceps purpurea
Artificial Honey Dew-Preparation
Spraying of the Rye Field

Ergot Alkaloid Extraction from Claviceps Species
Ergot Alkaloids from Commercial Ergot
Isolation of Lysergic Acid from Claviceps paspali Cultures
Extracting Alkaloids from Ergot of Rye
Isolation of Ergot Alkaloids from Claviceps purpurea
Culture Suspensions Using Clay
Preparing Lysergic Acid from Paspalic Acid

Claviceps purpurea Cultivation
Claviceps purpurea Cultivation and Strain Selection
Preparation of ! Media
Inoculation of Cultures
Strain Selection
Ergot Preparation
Production of Ergot Alkaloids
Growth Conditions for Claviceps Species
Relationship Between Growth and Nutrient Concentration
Conditions for Alkaloid Synthesis
Preparation of Ergot Alkaloids
Preparation of Ergotamine and Ergocryptine
Purification of the Product
Fermentation Process
Fermentation of Ergoline Derivatives

Host Plants for Claviceps paspali
Life History of Claviceps paspali
Host Plants to Claviceps paspali
Host Plants Resistant to Artifictial Inoculation
Ergot Size in Reference to Size of Spikelet
Paspalum longipilum
Paspalum dilatatum (Dallis Grass)
Paspalum uervilli (Vasey Grass)
Paspalum pubenscens
Paspalum pubiflorum
Paspalum ciliatifolium
Paspalum distichum L. (Knot-grass)
Paspalum notatum (Bahia Grass)
Paspalum laeve (Field Paspalum)
Paspalum langei
Paspalum floridanum

Claviceps paspali Cultivation
Alkaloid Derivatives of Lysergic Acids
4 Litre Fermentor
Microbiological Production of Lysergic Acid Derivatives
Production of Ergot Alkaloids
Colony Characteristics of Claviceps paspali ATCC 14988
Heterocyclic Carboxylic Acids Production

Preparation of Diethylamine from Ethanol
Separation of Diethylamine
Process of Separating Lower Alkylamines
Preparation of Diethylamine
Preparation of Ethylamine and Diethylamine
Preparation of Ethyl Bromide (1-Bromoethane) from Sodium Bromide and Ethyl Alcohol

Anhydrous Hydrazine from Hydrazine Sulfate
Production of Hydrazine Sulfate
Hydrazine Sulfate
Anhydrous Hydrazine
Anhydrous Hydrazine from Hydrazine Hydrate
Manufacture of Hydrazine
Hydrazine Hydrate 40-45%
Preparation of 65% Hydrazine
Preparation of Anhydrous Hydrazine
High Purity Anhydrous Hydrazine
The Stabilisation of Hydrazine
Physical Constants; Safety Precautions

Tablet and Clearlight Manufacture
Tablet Manufacture in History by Joseph R. Wood
Molded Tablets (Tablet Triturates)
Tablet Triturate Machine
Trituration of Tablets
Compressed Tablets
Tableting Lysergic Acid Amides

Blotter Carrier
Thin Film Carrier: "Clearlight" or "Gel"
Preparation of Clearlight Carrier: "Sheeting"

LSD is an asset and essential reading for anyone interested in the application, synthesis and psychedelic history of d-lysergic acid diethylamide.

See all Editorial Reviews

Product Details

• Paperback: 246 pages
• Publisher: Thoth Pr (November 2003)
• Language: English
• ISBN-10: 0966312848
• ISBN-13: 978-0966312843
• Product Dimensions: 8.6 x 5 x 0.9 inches
• Shipping Weight: 1 pounds (View shipping rates and policies)
• Average Customer Review: 4.8 out of 5 stars  See all reviews (4 customer reviews)
• Amazon Best Sellers Rank: #576,632 in Books (See Top 100 in Books)

More About the Author

Discover books, learn about writers, read author blogs, and more.

Customer Reviews

Most Helpful Customer Reviews

38 of 38 people found the following review helpful:

5.0 out of 5 stars Best Book on LSD Synthesis Ever Written, May 10, 2004

By A Customer

This review is from: Lsd (Paperback)

LSD is truly an amazing book. No doubt the best book ever written on the subject of LSD synthesis. It is very comprehensive, describing the construction of all precursors from common materials. The illustrations are beautiful. There are quotes and descriptions from psychotherapists who personally used LSD in their practice. The text is small print, packed with multiple formulas that have been used by the actual manufacturers. Complete with graphic pictures of tablet machines and sheeting equipment. This first edition is sure to become a classic; collectible by all those interested in the subject of psychedelics. I really enjoy it and would recommend LSD (the book) to everyone.

41 of 48 people found the following review helpful:

5.0 out of 5 stars Mistakes in previous review, October 15, 2004

By 

k93 - See all my reviews
(VINE VOICE)   

This review is from: Lsd (Paperback)

The effect of LSD and other psychedelics is a fascinating area of study, and unfortunately, due to the failure of the legal system to keep up with the pace of neuroscience, very little research has been done in this area since the advent of modern scientific technology such as the fMRI (and what a shame it is!)

It is with that caveat that I must say the previous reviewer is either mistaken or simply not up-to-date with the current hypotheses as to how LSD and other indoleamine psychedelics affect the brain. Perhaps the previous reviewer may be interested in checking out the latest research, what little of it there is.

The idea that LSD is merely affecting the retinal cells does not make any sense in that it does not account for most of the subjective effects of the drug. Since sustained firing of retinal cells may account for the visual short-term sensory store (an effect that causes some degree of "trails" in all people) then perhaps LSD's effect of elongated "trails" is caused by this. However, it cannot account for anything else, and LSD certainly has myriad other effects: visual, auditory, emotional, cognitive, you name it.

Current literature states that LSD acts on a variety of 5-HT type (serotonin) receptors. The serotonin pathways originate in the raphe nuclei and spread throughout the cortical and sub-cortical areas; consequently, LSD may act on these pathways throughout the brain. Not only that, but LSD and similar compounds have been shown to have noradrenergic and dopaminergic effects, including effects on the locus coeruleus, a system that also extends pathways throughout the brain and acts as a modulator for such functions as emotion and arousal.

And finally, for many people, LSD truly is a mind-expanding experience. The effect it has certainly depends on the person taking the drug, their mindset, their openness to new experiences, etc. But regardless, LSD has the potential to, at the very least, shock the user into experiencing a new way of perceiving the world and the self, shaking to the core any previous assumptions that the world is exactly as they see it and they see it exactly as it is. For many, this can be truly valuable.

All that being said, this book is chock-full of information and as such is an extremely welcome addition to current psychedelic literature. This is a vastly under-studied topic, and new information whether related to neuroscience, or pure chemistry, or potentials for psychotherapy, is all extremely helpful for the growing academic and spiritual interest in this subject.

4 of 24 people found the following review helpful:

5.0 out of 5 stars Excellent book!, June 5, 2007

By 

crippled1 - See all my reviews

This review is from: Lsd (Paperback)

"I am truly fascinating and will now convince you of it by explaining how lsd affects the brain." Please, I'm sure you are fascinating but, could you just review the book?