T Lymphocytes in the Liver: Immunobiology, Pathology and Host Defense [Hardcover]

I. Nicholas Crispe (Editor)

Book Description

ISBN-10: 047119218X | ISBN-13: 978-0471192183 | Publication Date: January 15, 1999 | Edition: 1

T Lymphocytes in the Liver is the first book to offer a comprehensive review of the newly understood relationship between the liver and the immune system. This edited volume examines the immunobiology of T cells - the way their behavior in the liver differs from that in other organs, and, conversely, the liver's ability to effect changes in the activity of such immune cells. A number of relevant, cutting-edge issues are considered, including vaccine development, the liver's potential role in autoimmune tissue damage, tolerance and transplant rejection, and the use of animal organs for human patients. Contributing authors from diverse specialties discuss topics including:
* T cells expressing antigen receptors in the liver
* Active T cells in the liver
* Extrathymic T cells in the liver
* The induction of peripheral tolerance by portal vein administration of antigen
* The immunobiology of viral hepatitis
* Immunity to Listeria monocytogenes infection of the liver
* Malaria and the liver
* T cells and autoimmune liver disease
* Hepatic T cells in primary sclerosing cholangitis and autoimmune hepatitis

Editorial Reviews

From the Back Cover

T Lymphocytes in the Liver

Immunobiology, Pathology, and Host Defense

edited by I. Nicholas Crispe

Recent breakthroughs in the study of the liver have shown it to possess unique immunological properties, generating tremendous interest among physicians and researchers who deal with control of T cells, infectious diseases of the liver, immune tolerance, and transplantation.

T Lymphocytes in the Liver is the first book to offer a comprehensive review of the newly understood relationship between the liver and the immune system. This edited volume examines the immunobiology of T cells-the way their behavior in the liver differs from that in other organs, and, conversely, the liver's ability to effect changes in the activity of such immune cells. A number of relevant, cutting-edge issues are considered, including vaccine development, the liver's potential role in autoimmune tissue damage, tolerance and transplant rejection, and the use of animal organs for human patients. Contributing authors from diverse specialties discuss topics including
* T cells expressing ab antigen receptors in the liver
* Active gd T cells in the liver
* Extrathymic T cells in the liver
* The induction of peripheral tolerance by portal vein administration of antigen
* The immunobiology of viral hepatitis
* Immunity to Listeria monocytogenes infection of the liver
* Malaria and the liver
* T cells and autoimmune liver disease
* Hepatic T cells in primary sclerosing cholangitis and autoimmune hepatitis.

Timely, practical, and authoritative, T Lymphocytes in the Liver is an essential resource for hepatologists, immunologists, transplant researchers and clinicians, and for anyone who would like to learn more about this important topic in medical research.

Product Details

• Hardcover: 256 pages
• Publisher: Wiley-Liss; 1 edition (January 15, 1999)
• Language: English
• ISBN-10: 047119218X
• ISBN-13: 978-0471192183
• Product Dimensions: 9.4 x 6.2 x 0.7 inches
• Shipping Weight: 1.1 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #4,407,810 in Books (See Top 100 in Books)