Lymphocytes: A Practical Approach (Oxford India Collection) [Hardcover]

Sarah L. Rowland-Jones (Editor), Andrew J. McMichael (Editor)

Book Description

ISBN-10: 0199638179 | ISBN-13: 978-0199638178 | Publication Date: March 16, 2000 | Edition: 2

Cellular immunology is a rapidly moving field in which recent advances have made significant contributions to our understanding of the immune response to infection and malignancy. These in turn, have given rise to new therapeutic opportunities in areas such as vaccines and immunotheraphy. Many investigators have been discourages by the complicated protocols involved in cellular immunological studies, as illustrated, by the meticulous care required for the generation of antigen-specific T-cells. Lymphocytes: A Practical Approach (second edition) contains straight-forward protocols for well- established procedures in the study of lymphocytes including preparation and identification of lymphocytes, immortalization, cell and organ culture, and quantification assays. It also covers the recent technological advances which have revolutionised the field, such as the use of the Interferon-gamma ELISpot assay and peptide-HLA tetrameric assays to quantify antigen-specifidc T-cells directly from peripheral blood, without the need for in vitro culture, and molecular methods for accurate HLA typing.

Editorial Reviews

Review

"... the book contains extremly useful practical advice for studying lymphocytes in the laboratory..." Parasitology Today

About the Author

Sarah L. Rowland-Jones is at Institute of Molecular Medicine, Oxford. Andrew McMichael is at Institute of Molecular Medicine, Oxford.

Product Details

• Hardcover: 352 pages
• Publisher: Oxford University Press, USA; 2 edition (March 16, 2000)
• Language: English
• ISBN-10: 0199638179
• ISBN-13: 978-0199638178
• Product Dimensions: 9.3 x 6.4 x 1.1 inches
• Shipping Weight: 1.4 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #3,544,091 in Books (See Top 100 in Books)