Lyophilization: Introduction and Basic Principles [Hardcover]

Thomas A. Jennings (Author)

Book Description

Publication Date: August 31, 1999 | ISBN-10: 1574910817 | ISBN-13: 978-1574910810 | Edition: 1

Finding consistent, analytical discussions of processes and principles of lyophilization can be challenging and often frustrating. The first resource to gather information about the field, Lyophilization: Introduction and Basic Principles is still the book to have on lyophilization. Presenting information in an easy-to-read style, the book comprehensively and authoritatively covers the field. Using plain, unpretentious language, author Thomas A. Jennings pulls together information from diverse sources to provide an authoritative compendium of the lyophilization process and its basic principles. He provides important discussions about the nature of the container-closure system and the equipment, tools, and environments required. Case studies and examples of solutions illustrate the many ways problems can be addressed in the lyophilization process. The book covers: · Properties of lyophilized materials · Product formulation requirements and the thermal properties of formulations · Importance of process water · Phase changes · Thermal analytical methods · Freezing, primary, and secondary drying processes · Effect of vacuum freeze-dryers, both now and in the future Including over 150 illustrations, global symbols, and more than 350 references, this book is the complete guide to lyophilization, its analytical methods, measurement of process parameters, and equipment.

Product Details

• Hardcover: 646 pages
• Publisher: INFRMA-HC; 1 edition (August 31, 1999)
• Language: English
• ISBN-10: 1574910817
• ISBN-13: 978-1574910810
• Product Dimensions: 10.5 x 7.2 x 1.6 inches
• Shipping Weight: 2.9 pounds (View shipping rates and policies)
• Average Customer Review: 3.7 out of 5 stars  See all reviews (3 customer reviews)
• Amazon Best Sellers Rank: #446,712 in Books (See Top 100 in Books)

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Customer Reviews

Most Helpful Customer Reviews

1 of 1 people found the following review helpful:

2.0 out of 5 stars Disappointing, June 1, 2006

By 

Ron Hart "Ron" (San Francisco) - See all my reviews

This review is from: Lyophilization: Introduction and Basic Principles (Hardcover)

The book is comprehensive and somewhat useful as an introduction into the field. However, it has several flaws that make it fairly disappointing. The text is neither concise nor precise and some information is included that is of questionable value. (60 pages of experimental data in tabular form of thermal properties during cooling and warming of specific solutions are a waste of paper)
Some sections are sloppy. For example on page 64, describing the phase diagram of water, you will find an incomplete sentence, a description that doesn't match the figure (where is the dotted line A-E?), and a very poorly drawn phase diagram (water doesn't really freeze at -15 C at 100 kPa) The author frequently uses non-SI units.
A book in this price range should be properly edited and proof-read, in my opinion. This isn't, so I can't recommend it.

4.0 out of 5 stars More than introduction. Very useful, March 30, 2007

By 

Jorge Sassone "Jorge" (São Paulo, SP, Brazil) - See all my reviews

This review is from: Lyophilization: Introduction and Basic Principles (Hardcover)

I have found this book of much aid in my work as a scientist, in fact, some doubts I had were totally dissipated from the clear explanation and practical examples showed here. It is truth that there are some flaws, but it is apparent that they come from Editor, for example Figures showing diagrms etc.
Of great help is the fact that the author gives us access to his abundant collection of data wherefrom one can learn how to handle them. I would wish all the authors make like Dr. Jennings in that sense, for the readers will gain a better comprehension of the phenomena whereby they can obtain the necessary process understanding more easily.
Concerning arrangement of the Chapters, the author used the logic, thus the book was built in such a way that the understanding of one chapter provides the basis for the understanding of the following one.
For all the reasons states, I congratulate Dr. Thomas.A.Jennings and recommend his book.

6 of 10 people found the following review helpful:

5.0 out of 5 stars wonderful index included, June 4, 1999

By A Customer

This review is from: Lyophilization: Introduction and Basic Principles (Hardcover)

This is THE book on lyophilization (freeze-drying). The exemplary index makes this essential for manufacturers, researchers, academicians, and pharmaceutical companies.