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Macromolecular Crystallography, Part D, Volume 374 (Methods in Enzymology)
 
 
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Macromolecular Crystallography, Part D, Volume 374 (Methods in Enzymology) [Hardcover]

Charles W. Carter Jr. (Editor)

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Book Description

December 24, 2003 Methods in Enzymology (Book 374)
Accurate molecular structures is vital for rational drug design and for structure based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding.

* Phases
* Map interpretation and refinement
* Analysis and software

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Book Description

Accurate molecular structures is vital for rational drug design and for structure based functional studies directed toward the development of effective therapeutic agents and drugs.

About the Author

Edited by Charles W. Carter, Jr.

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Inside This Book (learn more)
First Sentence:
Johannes Bijvoet (1892-1980) made pioneering contributions to the determination of noncentrosymmetric structures. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
statistical density modification, automated structure solution, krypton binding, molecular graphics window, morph server, electron density histogram, noble gas derivatives, tertiary packing motifs, solvent flipping, histogram matching method, connected waypoints, density modification method, initial trial sites, anomalously scattering atoms, more stereochemical information, posttransition states, histogram matching procedure, structure factor set, xenon derivative, transition state ensemble, anomalous scatterers, refinement simulation, libration axes, mean phase error, substructure determination
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Acta Crystallogr, Methods Enzymol, Nucleic Acids Res, Protein Sci, Proteins Struct, New York, Acta Crvstallogr, Elsevier Inc, The Netherlands, Kluwer Academic, Academic Press, Protein Data Bank, Bijvoet-difference Fourier, Protein Eng, Ten Eyck, Monte Carlo, Collaborative Computational Project Number, Site Validation, Brookhaven National Laboratory, Cambridge University Press, National Science Foundation, San Diego, Trends Biochem, Department of Energy, John Wiley
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