This highly illustrated monograph provides a comprehensive study of the structure and function of proteins, nucleic acids and viruses using synchrotron radiation and crystallography. Synchrotron radiation is intense, polychromatic and finely collimated, and is highly effective for probing the structure of macromolecules. This is a fast-expanding field, and this timely monograph gives a complete introduction to the technique and its uses. Beginning with chapters on the fundamentals of macromolecular crystallography and macromolecular structure, the book goes on to review the sources and properties of synchrotron radiation, instrumentation and data collection. There are chapters on the Laue method, on diffuse X-ray scattering and on variable wavelength dispersion methods. The book concludes with a description and survey of applications including studies at high resolution, the use of small crystals, the study of large unit cells, and time-resolved crystallography (particularly of enzymes). Appendices are provided which present essential information for the synchrotron user as well as information about synchrotron facilities currently available. A detailed bibliography and reference section completes the volume. Many tables, diagrams and photographs are included.
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Book Description
Editorial Reviews
Review
'Those working directly in the field of macromolecular structure determination will find the volume indispensable.' Science
'... informative, well-produced, and profusely illustrated book.' Science
'... valuable compendium of current synchrotron sources and instrumentation ...' Physics Today
'... accessible to noncrystallographers ... a valuable reference text ...' Journal of the American Chemical Society
'This book will be their (synchrotron users) one essential reference.' Acta Crystallography
'(no researchers ) in macromolecular structure analysis should be without this book ...' Chemistry in Britain
'... informative, well-produced, and profusely illustrated book.' Science
'... valuable compendium of current synchrotron sources and instrumentation ...' Physics Today
'... accessible to noncrystallographers ... a valuable reference text ...' Journal of the American Chemical Society
'This book will be their (synchrotron users) one essential reference.' Acta Crystallography
'(no researchers ) in macromolecular structure analysis should be without this book ...' Chemistry in Britain
Book Description
This highly illustrated monograph provides a comprehensive study of the structure and function of proteins, nucleic acids and viruses using synchrotron radiation and crystallography. This is a fast-expanding field, and this timely monograph gives a complete introduction to the technique and its uses.
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Inside This Book
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Key Phrases - Statistically Improbable Phrases (SIPs):
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wavelength anomalous dispersion methods, wavelength normalisation, monochromatic geometry, optimised anomalous dispersion, point spread factor, double crystal system, angular reflecting range, protein crystal sample, rocking width, toroid mirror, protein crystallography station, platinum coated mirror, anomalous dispersion studies, monochromatic data collection, mosaic graphite, time resolved macromolecular crystallography, multipole wiggler, difference ratio method, diffuse scattering features, ribosome studies, monochromatic experiments, nodal spots, anomalously scattering atoms, oscillation camera, electronic area detector Key Phrases - Capitalized Phrases (CAPs): (learn more)
Photon Factory, Diffuse X-ray, Macmillan Magazines Ltd, Daresbury Laboratory, The Du Mond, Institute of Physics, Absorption of X-rays, The Harker, The Nobel Foundation, Oxford University Press, Compound Energy, Argonne National Laboratory, Daresbury Synchrotron Radiation Source Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
wavelength anomalous dispersion methods, wavelength normalisation, monochromatic geometry, optimised anomalous dispersion, point spread factor, double crystal system, angular reflecting range, protein crystal sample, rocking width, toroid mirror, protein crystallography station, platinum coated mirror, anomalous dispersion studies, monochromatic data collection, mosaic graphite, time resolved macromolecular crystallography, multipole wiggler, difference ratio method, diffuse scattering features, ribosome studies, monochromatic experiments, nodal spots, anomalously scattering atoms, oscillation camera, electronic area detector Key Phrases - Capitalized Phrases (CAPs): (learn more)
Photon Factory, Diffuse X-ray, Macmillan Magazines Ltd, Daresbury Laboratory, The Du Mond, Institute of Physics, Absorption of X-rays, The Harker, The Nobel Foundation, Oxford University Press, Compound Energy, Argonne National Laboratory, Daresbury Synchrotron Radiation Source Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
Citations (learn more)
12
books
cite this book:
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- Crystals and Life: A Personal Journey by Celerino Abad-Zapatero in Back Matter (1), Back Matter (2), and Back Matter (3)
- Practical Protein Crystallography, Second Edition by Duncan E. McRee on page 36, page 84, and page 185
- Methods of X-ray and Neutron Scattering in Polymer Science (Topics in Polymer Science) by Ryong-Joon Roe on page 80, and page 81
- Soft X-Rays and Extreme Ultraviolet Radiation: Principles and Applications by David Attwood on page 23, and page 407
- Modern Crystallography 2: Structure of Crystals (Modern Crystallography, Volume 2) (Pt. 2) by Boris K. Vainshtein in Back Matter
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