Malignant pleural mesothelioma, a malignancy due largely to asbestos exposure, represents an increasingly common challenge to clinical and medical oncologists, respiratory physicians, and cardiothoracic surgeons, as well as researchers in the field. The disease has yet to reach its peak and is expected to kill over 100,000 people worldwide. As malignant pleural mesothelioma gains in profile, Kenneth O'Byrne and Valerie Rusch present a comprehensive overview of the subject, aimed at all health care professionals who come into contact with patients with the disease. The book includes chapters on epidemiology, diagnosis, histopathology, radiology, surgery, chemotherapy, immune therapy, radiotherapy, and palliative medicine, written by an international team of contributors. A molecular biology section focuses on the carcinogenic effects of asbestos fibres and simian virus 40, angiogenesis and angiogenic growth factors, the immune response, and genetic abnormalities detected in the disease. Future therapies are also covered, as is a perspective on the distinct legal issues related to the disease. This highly-illustrated, full colour book provides the ultimate, timely resource on this devastating disease.
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"Anybody dealing with diffuse malignant mesothelioma, in either a research or clincial setting, should learn a great deal from this book in topics outside his or her own immediate specializations. As this clinically relentless disease continues to increase but has proven so refractory to therapy, any additional knowledge is welcome ideed, and this book is also welcome indeed."--Respiratory Care
"A comprehensive overview of the subject, aimed at all health care professionals who come into contact with patients with the disease."--Anticancer Research
About the Author
Dr Ken O'Byrne is President of the British Mesothelioma Trust. Professor Valerie Rusch, M.D. is currently Chief of Thoracic Surgery at Memorial Sloan-Kettering Cancer Center, where she also holds the William G. Cahan Chair. She is a member of the Editorial Boards for The Journal of Thoracic and Cardiovascular Surgery, The Journal of Clinical Oncology, The Oncologist, and Lung Cancer.
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