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The Management of Chemical Process Development in the Pharmaceutical Industry
 
 
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The Management of Chemical Process Development in the Pharmaceutical Industry [Hardcover]

Derek Walker (Author)

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Book Description

0470171561 978-0470171561 March 28, 2008 1
Here is a practical guide that not only presents insights into the organization and management of the disciplines involved in chemical process development but also provides basic knowledge of these disciplines, enabling process development practitioners to recognize and assimilate them in their work. This book illustrates practical considerations through many examples of the successful direction and integration of the activities of chemists, analysts, chemical engineers, and biologists, as well as safety, regulatory, and environmental professionals in productive teams. Moreover, this reference provides guidance on:
  • Directing and carrying out specific tasks and courses of action
  • Making and communicating clear and achievable decisions
  • Solving problems on the spot
  • Managing the administrative aspects of chemical process development

The author, Dr. Derek Walker, has directed chemical process development work for four decades, combining firsthand chemical synthesis experience with many other disciplines needed to create chemical processes. You will benefit from his advice and unique insights into:

  • Understanding the workings of matrix organizations
  • Defining missions and creating action plans
  • Developing interdisciplinary approaches to problem solving
  • Holding review meetings, revising goals, and motivating staff
  • Prioritizing programs and responses to emergencies

In addition, you'll learn how successful chemists, in collaboration with other disciplines, define the best (green) chemistry for process scale-up, including accommodating FDA requirements in the last process steps and addressing safety and environmental matters early in their work. Case studies provide incisive perspective on these issues. A chapter on recognizing and patenting intellectual property emphasizes the importance of comprehensive literature surveys and understanding invention. A chapter on the future challenges you to think beyond narrow constraints and explore new horizons.


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Editorial Reviews

Review

"A useful addition to the library of any process development chemist or engineer … .Highly readable." (Chemistry World, November 2008)

"Interesting reading … A nice overview of subject matter such as process safety, the environment, regulatory affairs and patents." (Scientific Update, September 2008)

"Derek Walker has distilled his 40 years of experience in process development in the pharma industry in one book." (TCE - The Chemical Engineer, May 2008)

From the Back Cover

Here is a practical guide that not only presents insights into the organization and management of the disciplines involved in chemical process development but also provides basic knowledge of these disciplines, enabling process development practitioners to recognize and assimilate them in their work. This book illustrates practical considerations through many examples of the successful direction and integration of the activities of chemists, analysts, chemical engineers, and biologists, as well as safety, regulatory, and environmental professionals in productive teams. Moreover, this reference provides guidance on:

  • Directing and carrying out specific tasks and courses of action

  • Making and communicating clear and achievable decisions

  • Solving problems on the spot

  • Managing the administrative aspects of chemical process development

The author, Dr. Derek Walker, has directed chemical process development work for four decades, combining firsthand chemical synthesis experience with many other disciplines needed to create chemical processes. You will benefit from his advice and unique insights into:

  • Understanding the workings of matrix organizations

  • Defining missions and creating action plans

  • Developing interdisciplinary approaches to problem solving

  • Holding review meetings, revising goals, and motivating staff

  • Prioritizing programs and responses to emergencies

In addition, you'll learn how successful chemists, in collaboration with other disciplines, define the best (green) chemistry for process scale-up, including accommodating FDA requirements in the last process steps and addressing safety and environmental matters early in their work. Case studies provide incisive perspective on these issues. A chapter on recognizing and patenting intellectual property emphasizes the importance of comprehensive literature surveys and understanding invention. A chapter on the future challenges you to think beyond narrow constraints and explore new horizons.


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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
chemical development, regulatory affairs, therapeutic team, review branch, dilevalol hydrochloride, chemical development organization, extractive esterification, organic process wastes, betamethasone alcohol, toxicology batch, sulfoxide acid, chemical development group, process development chemists, boron intermediates, chemical process development, process development organization, simpler synthesis, steroid field, last process step, benzophenone hydrazone, ring expansion process, reductive hydrolysis, reaction calorimeter, new impurities, process development group
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, United States, New Jersey, Mexico City, John Wiley, Puerto Rico, Eli Lilly, Chou Tann, Tetrahedron Lett, Derek Walker Copyright, Arapahoe Chemicals, Bruce Shutts, Schering Corporation, Perkin Trans, Hal Wolkoff, Academic Press, Development Report, Martin Hultquist, Junning Lee, Bob Fildes, Arthur Best, Miguel Escobar, United Kingdom, Colorado State University, Schering-Plough Research Institute
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
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