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Management Principles for Building and Operating Biocontainment Facilities [Kindle Edition]

Daniel Fisher , Kelly Cole , Steve Westfall
4.8 out of 5 stars  See all reviews (4 customer reviews)

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Book Description

This practical, highly focused book is intended to be an authoritative planning and management reference for anyone associated with capital projects or facility operations involving biocontainment facilities for research on potentially dangerous biological pathogens and toxins. The emphasis is on research facilities that are designed to operate at biosafety containment Levels 3 or 4, which in the U.S. is designated BSL-3 or BSL-4 as defined by the CDC and NIH. Level 3 and 4 biocontainment is referred to in this book as high-containment. The book is directed especially to people of all disciplines who are new to high-containment; to managers or program leaders undertaking new initiatives to expand, build new, or modernize high-containment facilities; to administrators who need a clear picture of the level of institutional commitment that high-containment facilities entail; and to veterans in the field who have yet to codify their thinking on the elements of their successes or possibly even failures.
This is not a book about design details, specific floor plans, or detailed procedural protocols. Nor is it about science facilities in general. Rather, it is about the management of capital projects and operational programs that have specific high-containment program elements.
This book distills and codifies the experience, insights, and lessons learned of seasoned practitioners (facility planners, project directors, owners, end users, science program managers, and facility operators) who are immersed in the field of high-containment facility planning, construction, operation, and program management. They have experienced at first-hand the remarkable advancement that has occurred in the ten-year period 2002-2012 in the thinking and practice of delivering and operating safe environments for research involving dangerous biological pathogens and toxins. They share their management experiences, insights, and lessons learned in the form of 55 management principles for developing and operating successful high-containment facilities, important background information, personal testimonies and counsel, and guidelines and templates for planning and operations.
The management principles put forth in this book come in two types: Normative Principles (things to do or not to do), and Descriptive Principles (if you do or don't do this, expect the following outcome). It is intended that these principles will spur productive discussion among future project and management team members to shape successful project and management outcomes.
Appendices list all 55 of the book's management principles and a glossary of terminology pertaining to high-containment facilities.
The ten-year period – 2002 to 2012 – represents the most active, aggressive, and well-funded decade of high-containment facility growth in history. In this decade, major biocontainment laboratory facilities have been built or have undergone major upgrades in North America, Europe, Asia, Australia, and Africa, and hundreds of research universities and hospitals, government research agencies, private sector biopharmaceutical firms, diagnostic companies, and research institutes have completed or are currently modernizing or putting in place new facility capacity for high-containment research programs. Many of these facilities have now accumulated significant start-up, commissioning, and operational experience, which this book seeks to codify and chronicle for the benefit of future high-containment research programs.
All book royalties received by Tradeline are being donated to biocontainment facility operations training programs in Africa to offset the costs of visiting subject area experts who conduct special training courses in high-containment facilities management, maintenance, and operations.

Editorial Reviews

About the Author

Editors: Kelly Stefano Cole, Ph.D., Associate Director, Regional Biocontainment Laboratory Associate Professor of Immunology & Infectious Diseases and Microbiology University of Pittsburgh, Daniel J. Fisher, Assistant Vice Chancellor, Research Operations, Department of Facilities Management, University of Pittsburgh, and Steve Westfall, Ph.D, CEO Tradeline, Incorporated.

Product Details

  • File Size: 763 KB
  • Print Length: 158 pages
  • Page Numbers Source ISBN: 0615785913
  • Publisher: Dockside Sailing Press (January 17, 2013)
  • Sold by: Amazon Digital Services, Inc.
  • Language: English
  • ASIN: B00B2S0G3U
  • Text-to-Speech: Enabled
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  • Lending: Enabled
  • Amazon Best Sellers Rank: #580,541 Paid in Kindle Store (See Top 100 Paid in Kindle Store)
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Customer Reviews

4.8 out of 5 stars
4.8 out of 5 stars
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Most Helpful Customer Reviews
Format:Kindle Edition
This book is a welcome and essential source of diverse and instructive information for anyone involved in any aspect of involvement with biocontainment facilities; this whether working from a scientific, design, construction, facilities operation or maintenance perspective. It provides a complete first reference for the myriad and complex questions likely to come from designers, researchers, scientists, constructors or maintenance practitioners operating in this highly specialized field.

Over the past more than four years, I been intimately involved in the design building and commissioning of a completely new building which contains extensive BSL2 and BSL3 facilities. Our facilities team, in taking over responsibility now has to ensure that the facility operates safely and effectively and this reference source will provide an essential part of our toolkit. Given the knowledge and guidance herein, my only regret is that "Management Principles for Building and Operating Biocontainment Facilities' wasn't available to our project team five years ago!

Charles W Poole; Executive Director Physical Planning and Operations. University of Kwa Zulu Natal, South Africa.
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Format:Kindle Edition
The book is extremely well written as it touches upon many aspects of biocontainment facilities to include design, engineering, operations, training, risk assessment and other areas pivotal to successful and safe management and operation. Applied examples are provided throughout many of the chapters to increase relevance and utility. The Kindle format is easy to navigate and facilitates retrieval of the document. I would recommend this book to anyone contemplating construction or renovation of a containment facility, and especially to new users of a biocontainment facility.
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Format:Kindle Edition
I recently had an opportunity to read this ground-breaking book. In it, the editors have assembled an experienced crew of authors to discuss the most important aspects of planning, building and operating bio-containment facilities. They cover everything from planning and design to staffing and training. The lessons of years of experience are presented, with valuable information regarding typical operating budgets and maintenance costs. One of the most interesting sections for me, as a scientist who has spent the majority of his career working in a BSL-3 facility working with transgenic mice, human tissues, viral vectors and HIV, is the discussion of risk assessment and emergency response for high containment facilities. These chapters provided useful reminders regarding the importance of creating a safe work environment for BSL-3 employees to avoid potentially severe consequences.

I recommend this book to anyone currently using or planning to build a bio-containment facility.

Kent Smith, Scientist
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Format:Paperback|Verified Purchase
Wide variety of topics, well presented, but not all are relevant for my project role. However I would recommend it to anyone going to work in this field as it gives a good 360 degrees introduction.
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