Management of Prostate Cancer (Current Clinical Urology) [Hardcover]

Eric A. Klein (Editor)

Book Description

ISBN-10: 1588293041 | ISBN-13: 978-1588293046 | Publication Date: May 7, 2004 | Edition: 2

This thoroughly updated and revised edition of a widely acclaimed book provides concise and authoritative guidance to today's best therapeutic regimens for the diagnosis and treatment of prostate cancer. The authors explain the trends in diagnosis and mortality, new PSA isoforms for diagnosis, PSA screening, chemoprevention, biopsy techniques, sural nerve grafting, and hereditary prostate cancer. Additional chapters reflect progress in the management of locally advanced disease, the use of nomograms to predict outcomes, the medical management of erectile dysfunction, brachytherapy, and deciding between surgery and radiation. A compact disk accompanies the book for downloading the book to a PC or PDA.

Editorial Reviews

From The New England Journal of Medicine

Prostate cancer is the most common cancer in men. The increase in basic and clinical research on this type of cancer has been logarithmic. Although this is clearly a good thing from the standpoint of scientific advancement, it would take an entire day just to read the title of every recent article on prostate cancer. For this reason, a book on the subject is easily justified at least biennially to update physicians, including those who specialize in prostate cancer. Klein's Management of Prostate Cancer provides a balanced and comprehensive review.

This book covers the gamut of topics, from epidemiology and molecular genetics to treatment options for localized disease and disease that is refractory to hormone therapy. Overall, the 20 chapters are well written and provide a balanced view of the issues in diagnosis and treatment. The book's best feature is that it presents both sides of the picture. Several chapters stand out in this regard. Thompson and Foley present in a point-counterpoint style arguments that support or refute the effectiveness of screening, the clinical significance of detected disease, and the effectiveness of local treatment, as well as opposing views on cost and the quality of data from prospective trials. Their presentation clearly shows how the same information can be interpreted in opposite ways and why major organizations differ in their recommendations for screening.

Two equally excellent chapters are "Counseling the Patient on Choice of Therapy and Outcomes: Surgeon's Perspective," by Vashi and Montie, and "Counseling the Patient on Choice of Therapy and Outcomes: Radiation Oncologist's Perspective," by Hanks. As one would expect, the surgeons consider surgery the treatment of choice, and the radiation oncologist favors radiation therapy; the two views are defended with equal eloquence. These chapters will be especially helpful to patients who have spent a substantial amount of time researching their treatment options and who are confused about why they are receiving conflicting recommendations. Should further editions of this book be published, a chapter on the medical oncologist's perspective would be helpful, because an increasing number of patients consult a medical oncologist to help make the choice between surgery and radiation therapy.

A second feature of this book is its practical approach to the management of prostate cancer and the complications of treatment. In the chapter entitled "Contemporary Technique of Radical Retropubic Prostatectomy," Klein, Licht, and Jhaveri provide a good description of their surgical technique and discuss its pros and cons. The chapter has many detailed illustrations. The discussions of cost containment and "collaborative care pathways" in the chapter on perioperative management show how continuous-quality-improvement programs can influence practice patterns and improve both the quality of care and the education of medical providers. The chapters on therapy for voiding dysfunction and sexual rehabilitation provide very useful discussions of diagnostic evaluations and therapeutic options. Knowledge of treatment choices is especially important for primary care physicians who provide routine care for men with prostate cancer. A chapter on management of the complications of progressive prostate cancer would have been useful. Although there are many common problems associated with advanced cancer, such as fatigue, anemia, and weight loss, there are certain complications that, if not unique to prostate cancer, are more commonly encountered with this type of cancer than with other types. Suggested evaluations and potential interventions for spinal cord compression, gross hematuria that cannot be controlled or that is difficult to control, urinary frequency, disseminated intravascular coagulation, diffuse bone pain, and pancytopenia would have been helpful.

The third feature of this book is its emphasis on new horizons. In their chapter on gene therapy, Rashid and Sanda discuss vectors for gene delivery, molecular targets, and the results of preclinical and phase 1 trials. Many patients assume that gene therapy will soon be available and will provide a nontoxic cure, but these authors make it clear that gene therapy is only in its infancy and that expectations about it need to be realistic. In "Monoclonal Antibodies for Imaging and Therapy of Prostate Cancer," Bander discusses antibodies to the extracellular domain of prostate-specific membrane antigen. These antibodies bind with high affinity to prostate-cancer cells, are internalized, and have been genetically engineered to be nonimmunogenic. They have a substantial antitumor effect in preclinical models, and there is optimism about the planned clinical trials. Finally, Kamradt and Pienta describe the newest approaches to hormone-refractory prostate cancer, with the use of antiangiogenesis agents, differentiating agents, and antimetastatic therapies. These novel approaches reflect our expanding knowledge of the mechanisms underlying cell proliferation and disease progression in cancer and the renewed trend toward translational research.

Management of Prostate Cancer is an informative review, and most of the chapters should be readily understood by patients and physicians alike. The last two chapters, on the surgeon's and radiation oncologist's perspectives, would be valuable reading for any man with prostate cancer who must decide whether to undergo surgery or radiation therapy. The chapter on screening provides important insights for primary care physicians facing the problem of whether to recommend screening.

Nancy A. Dawson, M.D.
Copyright © 2000 Massachusetts Medical Society. All rights reserved. The New England Journal of Medicine is a registered trademark of the MMS. --This text refers to an out of print or unavailable edition of this title.

Review

"...a valued addition to the literature of prostate cancer. All treating these patients should find some value and useful information in this book; it is an important update of the first edition." - Doody's Health Sciences Book Review Journal

"This is a valued addition to the literature of prostate cancer. The clinical issues relevant to the disease are appropriately addressed and the book is one of the more current ones available. The authors are well recognized and their opinions in their respective chapters are presented clearly. All treating these patients should find some value and useful information in this book; it is an important update of the first edition." - Doody's Health Sciences Book Review Journal

Reviews of the first edition:
"Presently, early detection and treatment remain our best hope for the cure of this common disease. Dr. Klein has assembled an outstanding group of authors to contribute to Management of Prostate Cancer. Those who take the time to read it will have a much better understanding of the management of prostate cancer."-Foreword by Ralph A. Straffon, MD

"...Klein's Management of Prostate Cancer provides a balanced and comprehensive review...the 20 chapters are well written and provide a balanced view of the issues in diagnosis and treatment. The book's best feature is that it presents both sides of the picture...Thompson and Foley present in a point-counterpoint style arguments that support or refute the effectiveness of screening, the clinical significance of detected disease, and the effectiveness of local treatment, as well as opposing views on cost and the quality of data from prospective trials...A second feature of this book is its practical approach to the management of prostate cancer and the complications of treatment...The third feature of this book is its emphasis on new horizons...Management of Prostate Cancer is an informative review, and most of the chapters should be readily understood by patients and physicians alike. The last two chapters, on the surgeon's and radiation oncologist's perspectives, would be valuable reading for any man with prostate cancer who must decide whether to undergo surgery or radiation therapy. The chapter on screening provides important insights for primary care physicians facing the problem of whether to recommend screening."-The New England Journal of Medicine

"This book is a must read for any physician desiring a complete and up-to-date understanding of prostate cancer. All aspects of this variable, complex, and prevalent disease are discussed in the 20 chapters, with contributions from 43 clinicians involved in the diagnosis and treatment of prostate cancer...Outstanding discussions analyze risk factors and genetic markers...The Management of Prostate Cancer will provide the clinician with a current, complete snapshot of all issues involved in the diagnosis and management of this disease. It should be part of the library of all urologists. Pathologists, radiation oncologists, medical oncologists, surgical oncologists, and general surgeons will find this text very useful as a reference for the latest developments in this field."-Current Surgery

"The book offers recent survey in the field of prostate cancer epidemiology, risk factor, molecular markers, diagnostic procedures (including prostate biopsy), transrectal ultrasonography, computer tomography, magnetic resonance, the techniques of radical prostatectomy, radiotherapy and hormone therapy. Moreover there are on clinical practice oriented chapters, as interpretation of pathological findings, perioperative care, life quality evaluation, posttherapeutical urological disorders and modes of sexual rehabilitation, as well as adequate instructions of surgeon and radiotherapeutist for the period following adequate treatment....This publication represents an outstanding work devoted to the current state-of-the-art of the diagnosis and treatment of cancer, based on molecular-biological technology. It gives a comprehensive view about new achievements in molecular oncology and about innovations in research of human cancers. ...The book can be fully recommended for medical oncologists, surgeons and gynecologists engaged in cancer treatment as a guide in this new rapidly developing topic....The book offers an up-to-date information on prostate cancer diagnostics and treatment and can be fully recommended to all physicians, especially to urologists, radiotherapeutists and oncologists."- Neoplasma

"...this book is a comprehensive and concise update of the current knowledge of prostatic cancer....includes up-to-date information on the evaluation and treatment as well as the molecular biology, epidemiology and pathology of prostate cancer. Surgical treatment, radiation therapy, hormonal therapy, gene therapy and other therapeutic modalities are emphasized. Issues of early detection, quality of life and complications after treatment, and patient counseling are also broadly discussed....The strength of this book lies in its well-balanced and concise review of current diagnostic and therapeutic methods. Most of the illustrations and tables are good, and the references are current....The often ignored topic of hormone refractory prostate cancer is well presented....this book is practical, well illustrated and of value for those who would like to have a better understanding of the management of prostate cancer. It is a worthwhile resource for the general urologist, radiation and urological oncologists as well as for residents in training." - Journal of Urology

"...this book is both timely and useful for all clinicians who wish to obtain a clear and up-to-date account of the management of prostate cancer." - British Journal of Surgery

See all Editorial Reviews

Product Details

• Hardcover: 688 pages
• Publisher: Humana Press; 2 edition (May 7, 2004)
• Language: English
• ISBN-10: 1588293041
• ISBN-13: 978-1588293046
• Product Dimensions: 10.2 x 7.2 x 1.5 inches
• Shipping Weight: 3.5 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #1,155,586 in Books (See Top 100 in Books)