Mass Spectrometry: A Textbook [Hardcover]

Jürgen H. Gross (Author)

Book Description

ISBN-10: 3540407391 | ISBN-13: 978-3540407393 | Publication Date: June 1, 2006

Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.

Editorial Reviews

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From the reviews:

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Review by J. Allison, College of New Jersey

"With dozens of works available in the ever-expanding field of mass spectrometry, the ideal work still seems, as Gross (Univ. of Heidelberg) states, to be missing. Gross does an excellent job of constructing a book that is surprisingly comprehensive, scientifically accurate, and is packed with figures, photos, and examples. All of the standard topics are covered, including common ionization methods, instrumentation, ion chemistry, and "hot" methods. The writing is very informal, which may make it more accessible to readers new to the field. At times, figures are not adequately explained, and sections that need to be included for completeness are short; however, there are few options when trying to present so much in a single volume. Gross does this well. The book is well written and packed with useful citations and information. Photos of equipment are very instructive and useful. Teachers of mass spectrometry will find this to be a pleasant surprise, and a top contender as the resource for a course in this field. Summing Up: Highly recommended. General readers; upper-division undergraduates through professionals."

"It represents a long-awaited update in the literature on general mass spectrometry … . is very well referenced and … clearly set out … . provides a most valuable reference for the professional mass spectrometrist and for users at all levels. … ideal text for new graduates, setting out on a career in mass spectrometry, and provides a well-rounded and comprehensive overview of the field. … will undoubtedly take its place among classical mass spectrometry texts." (Peter Cullis, Chemistry in Australia, June, 2005)

"No single author has attempted to compile such a comprehensive treatise. … Each chapter offers a detailed discussion with many illustrations facilitating understanding. … The book is admirably free from errors … . highly informative and up-to-date covering all aspects of organic mass spectrometry. It can be used both as a reference book and as a guide for those persons who want more than a superficial knowledge of this important field." (Herbert Budzikiewicz, Analytical and Bioanalytical Chemistry, Vol. 381, 2005)

"Starting from first principles this textbook takes the reader through the design of mass analysers and ionisation methods al the way to mass spectral interpretation and coupling techniques. … This is an ideal textbook for students and professionals as well as newcomers to the field of mass spectrometry. It provides a balanced mixture of practical and theoretical background, featuring a clear layout and a wealth of high-quality figures, and an extensive reference list at the end of each chapter." (Stephen Mee, Materials World Inc., Vol. 13(5), 2005)

"It is a very thorough book which looks at all aspects of the subject … . It is generously illustrated with figures, schemes, spectra, tables and graphs. Every term is defined as it arises … equations are derived and experimental data plotted. It is fully referenced to original literature, and has a good index." (E. D. Morgan, Chromatographia, Vol. 61(5-6), 2005)

"An up-to-date text-book on mass spectrometry that not only contains a thorough treatment of the various aspects and methods of this technique, but also provides a comprehensive coverage of the relevant literature. It is an excellent work … . From the conception of the book and its detailed contents it is clear that the author has a deep understanding of this field. … can be recommended unreservedly as a textbook and reference source for chemists, especially organic chemists." (Manfred Hesse, Angewandte Chemie International Edition, Vol. 43(35), 2004)

"It is amazing, how much detailed information he is able to pack into compact chapters without oversimplifying or loosing precision or clarity. … excellently illustrated with a large number of straight-to-the-point graphics ... . definitively is worth reading for a broad readership … . I will certainly recommend it to my own coworkers. … one of the best textbook on mass spectrometry I have seen so far. It may serve excellently as a basis for teaching lecture courses on mass spectrometry." (Christoph A. Schalley, International Journal of Mass Spectrometry, Vol. 235, 2004)

"The book entitled ‘Mass Spectrometry – A Textbook’ provides an overview of the principles and technology that define mass spectrometry (MS). … The book is comprised of twelve, well written chapters with easy-to-follow diagrams, figures and appendices. … Cross-disciplinary students or researchers at the biology-chemistry interface would find this book rewarding … ." (Aine Behan, Proteomics, Vol. 5 (17), 2005)

From the Back Cover

Mass spectrometry today is an indispensable tool in chemistry and life sciences. This book is tailored to guide students and professionals as well as novices to mass spectrometry from other fields. Mass Spectrometry - A Textbook will guide them from their first steps to the successful application of mass spectrometry in their daily work in research. Starting from the very principles of gas phase ion chemistry and isotopic properties, it leads through the design of mass analyzers and the ionization methods in use to mass spectral interpretation and coupling techniques. Step by step the readers will understand how mass spectrometry works and what it can do as a powerful tool in their hands. The book comprises a balanced mixture of practice-oriented information and theoretical background. The clear layout, a wealth of high quality figures and a database with exercises and solutions freely accessible via the publisher’s web site, support the reader’s understanding.

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Product Details

• Hardcover: 518 pages
• Publisher: Springer (June 1, 2006)
• Language: English
• ISBN-10: 3540407391
• ISBN-13: 978-3540407393
• Product Dimensions: 9.5 x 6.3 x 1.4 inches
• Shipping Weight: 2 pounds
• Average Customer Review: 4.2 out of 5 stars  See all reviews (4 customer reviews)
• Amazon Best Sellers Rank: #1,073,704 in Books (See Top 100 in Books)

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Most Helpful Customer Reviews

1 of 1 people found the following review helpful:

5.0 out of 5 stars Mass Spectrometry, February 18, 2010

By 

Marta L. Limberg (Little Rock Area, Arkansas USA) - See all my reviews
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This review is from: Mass Spectrometry: A Textbook (Hardcover)

Concise, has the scientific information necessary for a complete understanding of what mass specometry entails from the practicing scientist's view. This book is a graduate level requiring an understanding of the physics involved and the associated mathematics. Would be a good reference for any laboratory using mass spectrometry on a daily basis.

3 of 4 people found the following review helpful:

2.0 out of 5 stars Overly verbose - a beginner in the field may be overawed, May 23, 2006

A Kid's Review

This review is from: Mass Spectrometry: A Textbook (Hardcover)

Although many books dealing with organic mass spectrometry (the present oeuvre is restricted to this field in a broad sense) have appeared over the years, since Beynons 1960 classic publication no single author has attempted to compile such a comprehensive treatise. The book comprises twelve chapters including basic principles (quasi-equilibrium theory, energy considerations--for example bond strengths, ionization energies, gas-phase basicities, etc., gas-phase ion chemistry, isotopes), instrumentation (ion separation in time-of-flight, sector-field, quadrupole, ion-trap, and ICR instruments), specifically electron ionization and in detail subsequent fragmentation of organic ions (specific processes, for example -cleavage or McLafferty rearrangement, are grouped together), alternative ionization techniques (chemical ionization, field ionization and desorption, fast atom bombardment and related techniques, MALDI, electrospray), and, in the closing chapter, so-called hyphenated methods (combinations of mass spectrometry with chromatographic methods and tandem mass spectrometry). Each chapter ends with an ample reference list comprising books and review articles and original publications. An appendix contains lists of elements and their isotopic composition, isotope patterns, characteristic fragments observed in electron-ionization spectra, and frequently encountered impurities.

Each chapter offers a detailed discussion with many illustrations facilitating understanding. Reference is always given to the original literature (as recent as 2003, as checks showed). The text is, however, occasionally somewhat verbose. In general the treatment of the various topics is of a thoroughness that it can be used also by advanced users of mass spectrometry for reference and deeper understanding. There are only few exceptions: thus the discussion of chemical ionization is essentially restricted to proton transfer, charge exchange, and electron capture whereas other reagent gases are just mentioned en passant.

Although many practical hints are interspersed in the text, a beginner in the field may be overawed by the wealth of information and ask, What should I do now? For example, in the over-detailed discussion of isotopes and accurate mass measurements there is no indication how to approach the list of elemental compositions obtained in daily practice (e.g. the nitrogen rule is discussed only many chapters later without any reference here).

H. Budzikiewicz

5.0 out of 5 stars Made to measure, July 8, 2006

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Paul Verheecke (Brussels, Belgium) - See all my reviews
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This review is from: Mass Spectrometry: A Textbook (Hardcover)

In the preface the reader is warned. If you know nothing about MS, you'll need to read it cover to cover, skipping the details of no interest to you. If you know some MS, just go to the chapter(s) that are interesting to you.

Used that way, it is an excellent book. Having some experience in GC, this book was to me a first choice because most books on GC-MS are pretty outdated.