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The Mathematical Theory of Selection, Recombination, and Mutation (Wiley Series in Mathematical & Computational Biology)
 
 
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The Mathematical Theory of Selection, Recombination, and Mutation (Wiley Series in Mathematical & Computational Biology) [Hardcover]

R. Bürger (Author)
5.0 out of 5 stars  See all reviews (1 customer review)

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Book Description

0471986534 978-0471986539 November 27, 2000 1
"It is close to being a masterpiece...could well be the classic presentation of the area." Warren J. Ewens, University of Pennsylvania, USA
Population genetics is concerned with the study of the genetic, ecological, and evolutionary factors that influence and change the genetic composition of populations. The emphasis here is on models that have a direct bearing on evolutionary quantitative genetics. Applications concerning the maintenance of genetic variation in quantitative traits and their dynamics under selection are treated in detail.
* Provides a unified, self-contained and in-depth study of the theory of multilocus systems
* Introduces the basic population-genetic models
* Explores the dynamical and equilibrium properties of the distribution of quantitative traits under selection
* Summarizes important results from more demanding sections in a comprehensible way
* Employs a clear and logical presentation style
Following an introduction to elementary population genetics and discussion of the general theory of selection at two or more loci, the author considers a number of mutation-selection models, and derives the dynamical equations for polygenic traits under general selective regimes. The final chapters are concerned with the maintenance of quantitative-genetic variation, the response to directional selection, the evolutionary role of deleterious mutations, and other topics.
Graduate students and researchers in population genetics, evolutionary theory, and biomathematics will benefit from the in-depth coverage. This text will make an excellent reference volume for the fields of quantitative genetics, population and theoretical biology.

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Editorial Reviews

Review

"an excellent reference volume" (Zentralblatt Math, Vol. 959, No. 9 2001)

"...Burger's text is without equal. This is a book that should grace shelves in both mathematics and biology...that provides yet another point of contact for two communities whose interests can only grow closer..." (SIAM Review, Vol. 43, No. 4)

"This is a book that should grace shelves in both mathematics and biology departments." (Society for Industrial Applied Mathematics Review, Vol.43. No.4 2001)

"...it is such a comprehensive compendium that it will become the first port of call for any mathematician..." (The Statistician, Vol. 51, No.2, 2002)

"...the models described here provide a fundamental underpinning to our understanding of the properties of quantitative genetic variation...." (Journal of Evolutionary Biology, Vol. 14, 2001)

"...a major and significant piece of work..." (Genetical Research)

From the Back Cover

The Mathematical Theory of Selection, Recombination, and Mutation R. B?rger University of Vienna, Austria "It is close to being a masterpiece...could well be the classic presentation of the area." Warren J. Ewens, University of Pennsylvania, USA Population genetics is concerned with the study of the genetic, ecological, and evolutionary factors that influence and change the genetic composition of populations. The emphasis here is on models that have a direct bearing on evolutionary quantitative genetics. Applications concerning the maintenance of genetic variation in quantitative traits and their dynamics under selection are treated in detail.
* Provides a unified, self-contained and in-depth study of the theory of mutilocus systems
* Introduces the basic population-genetic models
* Explores the dynamical and equilibrium properties of the distribution of quantitative traits under selection
* Summarizes important results from more demanding sections in a comprehensible way
* Employs a clear and logical presentation style
Graduate students and researchers in population genetics, evolutionary theory, and biomathematics will benefit from the in-depth coverage. This text will make an excellent reference volume for the fields of quantitative genetics, population and theoretical biology. Visit Our Web Page! http://www.wiley.com/

Product Details

  • Hardcover: 422 pages
  • Publisher: Wiley; 1 edition (November 27, 2000)
  • Language: English
  • ISBN-10: 0471986534
  • ISBN-13: 978-0471986539
  • Product Dimensions: 9.5 x 6.5 x 1.1 inches
  • Shipping Weight: 2.1 pounds (View shipping rates and policies)
  • Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
  • Amazon Best Sellers Rank: #3,144,637 in Books (See Top 100 in Books)

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0 of 1 people found the following review helpful:
5.0 out of 5 stars WORLD OF MATHEMATICAL GENETICS.... EKREM AYNA, June 13, 2005
By 
Mustafa Bac (TURKEY ÝZMÝR) - See all my reviews
(REAL NAME)   
This review is from: The Mathematical Theory of Selection, Recombination, and Mutation (Wiley Series in Mathematical & Computational Biology) (Hardcover)
Well It is different than quantitative genetics, forget about the statistical work,forget the statistical rules. Now a new subject exists. Mathematical genetics (NOT QUANTITATIVE GENETICS). This book is a must for every one who is interested in genetics and who is planning a life for it. The book its self is not highly related with diagnosis genetics but IF YOU WANT TO UNDERSTAND THE THEORY OF GENETICS GET THIS BOOK WELL IT MAYBE EXPENSIVE BUT DO NOT FORGET THAT YOU WÝLL BUY ONCE NOT TWICE :) BUY IT DO NOT THINK MUCH AS I DID
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Inside This Book (learn more)
First Sentence:
Population genetics is concerned with the study of the genetic composition of populations. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
equilibrium genetic variance, equilibrium mean fitness, apparent stabilizing selection, exponential selection, hidden pleiotropic effects, symmetric viability model, polymorphic fraction, variance rye, multivariate cumulants, quadratic fitness function, expected genotypic value, multiplicative fitness model, additive quantitative trait, mutation distribution, equilibrium variance, epistatic deviations, diallelic case, pure selection model, pleiotropic model, synergistic epistasis, mating diploid population, total mutation rate, fittest allele, weak epistasis, segregation load
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Fundamental Theorem of Natural Selection, Hardy-Weinberg Law, Maynard Smith, Kimura's Maximum Principle, Robertson's Secondary Theorem of Natural Selection
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