In recent years, major developments have increased understanding of various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. These proceedings highlight recent developments in lymphocyte development, Ig gene rearrangements and somatic hypermutation, chromatin structure modification, B lymphocyte signaling and fate, receptor editing, and autoimmunity.
Mechanisms of Lymphocyte Activation and Immune Regulation XI
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antibody diversification enzyme, directed actin polymerization, receptor editing, hypermutation targets, fidelity pol, cell fate choice, induced deaminase, polymerase switch, chain gene loci, class switch recombination, cell hyporesponsiveness, protein vaccination, rearrangement machinery, somatic hypermutation, plasma cell differentiation, abasic sites, rearranged allele, plasmacytic differentiation, site bypass, cell fate specification, cytidine deaminase, memory compartment, chain loci, antigen receptor signaling, replication foci Key Phrases - Capitalized Phrases (CAPs): (learn more)
Exp Med, Proc Natl Acad Sci, Nat Immunol, Annu Rev Immunol, Biol Chem, David Savitsky, Nat Rev Immunol, Aid Somatic Hypermutation, Cell Evolution, New York, Immunol Rev, Int Immunol, Reiko Shinkura, Christine Grimaldi, Genes Dev, Howard Hughes Medical Institute, Mol Cell Biol, Regulation of Aid Function In Vivo, Clin Invest, Developmental Fate Decisions, Ursula Storb, Uttiya Basu, Chain Gene Loci of the Mouse, Curr Opin Immunol, Fritz Melchers New!
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Front Cover | Table of Contents | First Pages | Index | Surprise Me!
antibody diversification enzyme, directed actin polymerization, receptor editing, hypermutation targets, fidelity pol, cell fate choice, induced deaminase, polymerase switch, chain gene loci, class switch recombination, cell hyporesponsiveness, protein vaccination, rearrangement machinery, somatic hypermutation, plasma cell differentiation, abasic sites, rearranged allele, plasmacytic differentiation, site bypass, cell fate specification, cytidine deaminase, memory compartment, chain loci, antigen receptor signaling, replication foci Key Phrases - Capitalized Phrases (CAPs): (learn more)
Exp Med, Proc Natl Acad Sci, Nat Immunol, Annu Rev Immunol, Biol Chem, David Savitsky, Nat Rev Immunol, Aid Somatic Hypermutation, Cell Evolution, New York, Immunol Rev, Int Immunol, Reiko Shinkura, Christine Grimaldi, Genes Dev, Howard Hughes Medical Institute, Mol Cell Biol, Regulation of Aid Function In Vivo, Clin Invest, Developmental Fate Decisions, Ursula Storb, Uttiya Basu, Chain Gene Loci of the Mouse, Curr Opin Immunol, Fritz Melchers New!
Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
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