Medical Genetics, 3e [Paperback]

Lynn B. Jorde (Author)

Book Description

ISBN-10: 0323020259 | ISBN-13: 978-0323020251 | Publication Date: August 5, 2003 | Edition: 3

This is one of the few medical genetics texts on a 2-year revision cycle. It provides up-to-date information that can be read, retained, and applied with ease! The 3rd Edition covers pharmacogenomics, the societal implications of technologies, the Human Genome Project, cloning, genetic enhancement, and embryonic stem cell research, new tumor suppressor genes and oncogenes, and more. Mini-summaries, study questions, suggested readings, and a detailed glossary facilitate review of the material. Clinical relevance is demonstrated in over 230 photographs, illustrations, and tables as well as boxes containing patient/family vignettes. Its coverage includes ethical, legal, and social issues and clinical commentary on important genetic diseases. A companion web site offers continuing updates and a wealth of additional features.

• Features mini-summaries that appear in bold throughout each chapter.
• Supplies study questions and suggested readings at the end of each chapter.
• Contains a detailed glossary at the end of the book.
• Offers Clinical Commentary boxes that present detailed coverage of the most important genetic diseases and provide examples of modern clinical management.
• Demonstrates clinical relevance with boxed patient/family vignettes and coverage of ethical, legal, and social issues.
• Provides visual reinforcement and easy access to key information with over 230 photographs, illustrations, and tables.
• Includes a companion website with continuing content updates, additional clinical images, and more!

• Explores new technologies, including microarrays (e.g., DNA chips) and PCR-free detection of polymorphisms.
• Offers new material on pharmacogenomics, a field of study based on the principles of pharmacogenetics where genetic variation is assessed in order to predict a patient's response to specific drugs, including potential adverse reactions.
• Includes a new chapter, Genetics and Society, that discusses privacy, discrimination, and the societal implications of new genetic technologies
• Devotes a new section to the advances made possible by The Human Genome Project, such as the use of genomics databases to identify disease-causing genes.
• Contains a new section on Human Cloning, Genetic Enhancement, and Embryonic Stem Cell Research.
• Updates the Cancer Genetics chapter with information on new tumor suppressor genes and oncogenes, including discussion of their roles in carcinogenesis
• Expands the section, The Genetics of Common Diseases, with new information on genes predisposing to hypertension, type 2 diabetes, Alzheimer's disease, obesity, heart disease, and stroke.

Editorial Reviews

About the Author

Lynn B. Jorde, PhD, University of Utah Health Sciences Center, Salt Lake City, Utah

Product Details

• Paperback: 384 pages
• Publisher: Mosby; 3 edition (August 5, 2003)
• Language: English
• ISBN-10: 0323020259
• ISBN-13: 978-0323020251
• Product Dimensions: 11 x 8.5 x 0.6 inches
• Shipping Weight: 2 pounds
• Average Customer Review: 4.0 out of 5 stars  See all reviews (9 customer reviews)
• Amazon Best Sellers Rank: #1,540,706 in Books (See Top 100 in Books)

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Customer Reviews

Most Helpful Customer Reviews

10 of 10 people found the following review helpful:

5.0 out of 5 stars Best Succinct Text for Medical Genetics, October 22, 2007

By 

Robert Best (Columbia, SC) - See all my reviews
(REAL NAME)   

This review is from: Medical Genetics Updated Edition for 2006 - 2007: With Student Consult Online Access, 3e (Paperback)

I have been teaching medical genetics to medical students and graduate students for more than twenty years, and I have been using the Jorde text for teaching medical students since it was first published.

This text is the most succinct text available to my knowledge on the topic of medical genetics. This is perfect for medical students who have relatively little time in their schedules for genetics (16 lecture hours versus 48 hours for graduate students). The text is very clear, has great examples, ties in medical applications with the scientific explanations of principles, and has a wide array of online resources readily available. With very little exception, every page is worth the reading for medical students, and is helpful for them in learning what they need to know to become fully conversant in medical genetics and well acquainted with the general principles and emerging technologies. [I wish the cytogenetics chapter were illustrated better, but this is a minor weakness relative to the other strengths in the text.]

This is not the best text available for graduate students in clinical or medical genetics if the text is to be used alone (i.e. not supplemented with articles to add deeper levels of details). For students with a full 3-credit graduate course in medical genetics, it does not have quite sufficient depth, in my opinion. I don't have any significant experience teaching undergraduates, and will leave that area to others.

All in all, these authors have put together the clearest and most concise resource on medical genetics, and I highly recommend it for any audience whose needs are for efficient and palatable material on the principles of medical genetics.

12 of 13 people found the following review helpful:

5.0 out of 5 stars An excellent preclinical book, August 15, 2002

By A Customer

This review is from: Medical Genetics: Revised Reprint, 2e (Paperback)

This book was intended to prepare medical students to understand the basic science principles that form the foundation of clinical genetics. It is not intended to be a clinical handbook. It does an excellent job showing how the clinical genetic diseases illustrate the scientific principles of genetics. I think that it is very well written, and forms a foundation to pursue more clinical studies.

22 of 29 people found the following review helpful:

1.0 out of 5 stars Medical Genetics, December 31, 1999

By 

medical student (Phoenix, AZ) - See all my reviews

This review is from: Medical Genetics (Paperback)

This book is extremely limited in discussing how these genetic disorders manifest themselves clinically. I would not recommend this book for students who plan to apply their knowledge in the clinical setting. Explanations of certain genetic terms are not always clearly defined nor are certain biologic processes such as meiosis. Overall, a poorly written book for anyone but a graduate student of genetics.