Medicinal Natural Products: A Biosynthetic Approach [Paperback]

Paul M. Dewick (Author)

Book Description

ISBN-10: 0471496405 | ISBN-13: 978-0471496403 | Publication Date: December 15, 2001 | Edition: 2

Medicinal Natural Products, Second Edition is a comprehensive guide providing information on all classes of natural products in medicine. It builds upon fundamental chemical principles and demonstrates a unique integration of plant, microbial and animal natural products in one volume. The text guides the reader through a wealth of diverse natural metabolites used in medicine with sources, production methods, use as drugs and modes of action all extensively covered. Taking a chemistry based approach it combines traditional pharmacognosy with medicinal chemistry. The structure is user-friendly and includes the acclaimed grey boxes on groups of products and detailed mechanistic explanations.
* Adopts a novel biosynthetic theme rather than a traditional descriptive approach
* Includes extensive further reading at the end of the chapter
* Thoroughly revised and updated to incorporate comprehensive coverage of plant, microbial and animal products
* Includes the latest developments in the field
* New material on genetic manipulation of biosynthetic pathways and non-mevalonate pathway to terpanoids
* User-friendly format including extensive use of chemical schemes with annotated mechanistic explanations

Editorial Reviews

Review

"The book is highly recommended to all medicinal and natural products chemists and to any others involved with the products of these pathways. Although the hard-cased edition is inexpensive, a paperback edition is planned for students. They will both prove to be favored lasting additions to personal libraries." (Journal of Medicinal Chemistry, Vol. 45, No. 10)

"...comprehensive guide to pharacognosy..." (SciTech Book News, Vol. 26, No. 2, June 2002)

"...this updated edition is an excellent book..." (Pharmaceutical Research, Vol. 19, No. 12, December 2002)

"The price of the paper-back will allow not only to have it in the library but also on the personal bookshelf." (Journal of Plant PhysiologyNo.159, 2002)

From the Publisher

Pharmacologically active natural products from plants, microorganisms and animals have been used for centuries in the treatment of diseases. Within the science of pharmacognosy early herbal remedies and animal extracts have been evaluated and analysed to produce both modified (semi-synthetic) extracts and synthetic analogues. This is a concise and informative textbook which provides a comprehensive introduction to natural products in medicine from a biosynthetic point of view, rather than the more usual natural product class or activity viewpoint. --This text refers to an out of print or unavailable edition of this title.

See all Editorial Reviews

Product Details

• Paperback: 520 pages
• Publisher: Wiley; 2 edition (December 15, 2001)
• Language: English
• ISBN-10: 0471496405
• ISBN-13: 978-0471496403
• Product Dimensions: 9.8 x 7.6 x 1.3 inches
• Shipping Weight: 2.8 pounds
• Average Customer Review: 4.8 out of 5 stars  See all reviews (4 customer reviews)
• Amazon Best Sellers Rank: #9,814,375 in Books (See Top 100 in Books)

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Customer Reviews

Most Helpful Customer Reviews

8 of 8 people found the following review helpful:

5.0 out of 5 stars A MUST for anybody interested in natural products chemistry!, November 20, 1998

By A Customer

This review is from: Medicinal Natural Products: A Biosynthetic Approach (Paperback)

This text is absolutely superb and the only regret I have is that I did not write it myself! I have used it almost exclusively for the natural products chemistry component of our Bachelor of Pharmacy degree course and it comprehensively covers all of the major types of bioactive natural products. Anyone interested in Pharmacognosy will find the book an invaluable reference text. This book will be of great importance for future students of natural products chemistry. I thoroughly recommend its purchase!

5 of 5 people found the following review helpful:

5.0 out of 5 stars A Treasure, September 21, 2000

By 

Feras Alali, Ph.D (Jordan University of Science and Technology, Jordan) - See all my reviews

This review is from: Medicinal Natural Products: A Biosynthetic Approach (Paperback)

This is really a wonderful book. The author has a deep insight in world of biosynthesis and medicinal natural products. I have read it all and am using it as a text to my undergaduate pharmacy students. It is just what i was looking for. Thanks Dr. Dewick, i am looking forward to see your second edition soon of this book, maybe this time we will have more about biosynthesis techniques!

2 of 2 people found the following review helpful:

5.0 out of 5 stars A solid natural products text, January 28, 2008

By 

John M. Berger - See all my reviews
(REAL NAME)   

This review is from: Medicinal Natural Products: A Biosynthetic Approach (Paperback)

Medicinal Natural Products: A Biosynthetic Approach is an excellent text for the subject of natural products. There are a number of other text available but many (especially the older text) are really biochemical text disguised as natural products text (such as focusing on fatty acid biosynthesis rather than polyketide synthesis). In addition, many text are too short (I possess a text that describes biosynthetic reactions in 29 pages, a far too brief discussion of this complex field). This book is available in softcover at reasonable cost (a very desirable characteristic for students). I particularly enjoy the historical and pharmacological discussions of famous natural products. It is a good text for 1st year graduate students.