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Meningococcal Vaccines: Methods and Protocols (Methods in Molecular Medicine, 66) (Methods in Molecular Medicine)
 
 
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Meningococcal Vaccines: Methods and Protocols (Methods in Molecular Medicine, 66) (Methods in Molecular Medicine) [Hardcover]

Andrew J. Pollard (Editor), Martin C.J. Maiden (Editor)

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Book Description

Methods in Molecular Medicine June 1, 2001
Andrew Pollard and Martin Maiden have assembled an impressive collection of the latest molecular and cellular techniques for the development, evaluation, and implementation of vaccines to be used against this dreaded disease. The contributors-leading scientists, clinicians, and public health physicians-describe in detail the many approaches to vaccine design, as well as the assessment of immune response to vaccine candidates and novel vaccine formulations. Timely and comprehensive, Meningococcal Vaccines: Methods and Protocols provides the scientist, public health physician, epidemiologist, clinical microbiologist, and clinician with the essential tools to lay bare the secrets of the meningococcus, and to develop, evaluate, and implement successful new meningococcal vaccines.

Editorial Reviews

Review

"This volume is an impressive collection of the latest techniques in the development, evaluation and application of meningococcal vaccines. The easy-to-follow protocols each preceded by a brief introduction into the topic were provided by leading scientists in the field. Andrew Pollard and Martin Maiden did a great job in assembling these protocols into one volume - a work we all in the meningococcal field have waited for." - International Journal of Medical Microbiology.

"The strength of this text is that it provides a key reference source, enabling researchers in the field to avoid reinventing the wheel. The text also provides the basis for the development of new ideas. Each chapter takes a step-by-step approach with clearly set out notes highlighting the problem areas. All the chapters have comprehensive bibliographies, and are well structured. The text is easily accessible and is recommended to those who are seeking to critically appraise the field of meningococcal vaccines." - Epidemiology and Infection

"This book and its accompanying volume are well produced, easy to read and well edited. Andrew Pollard and Martin Maiden are to be congratulated in bringing together in these two volumes an enormous amount of information about this very important topical infection." -Molecular Biotechnology

From the Back Cover

The development of a comprehensive vaccine against Neisseria meningitidis, the causative agent of meningococcal disease, has remained elusive because of bacterial diversity and immunologic evasion. In Meningococcal Vaccines: Methods and Protocols, Andrew Pollard and Martin Maiden have assembled an impressive collection of the latest molecular and cellular techniques for the development, evaluation, and implementation of vaccines to be used against this dreaded disease. The contributors-leading scientists, clinicians, and public health physicians-describe in detail the many approaches to vaccine design, as well as the assessment of immune response to vaccine candidates and novel vaccine formulations. They also present as a test case the recent implementation of a new meningococcal vaccine in the United Kingdom. A companion volume, Meningococcal Disease: Methods and Protocols, contains detailed methods for diagnostic microbiology, bacterial characterization, epidemiology, host-pathogen interactions, and clinical studies. Timely and comprehensive, Meningococcal Vaccines: Methods and Protocols provides the scientist, public health physician, epidemiologist, clinical microbiologist, and clinician with the essential tools to lay bare the secrets of the meningococcus and to develop, evaluate, and implement successful new meningococcal vaccines.

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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
start buffer, separation columns, proteose peptone, meningococcal outer membrane vesicle vaccine, saccharide loading, bactericidal immune response, carrying multiple chromosomal copies, anticapsular antibody concentrations, ingococcal disease, virulent meningococci, meningitidis class, meningococcal antigens, lipooligosaccharide immunotype, bactericidal antibodies, membrane protein vaccine, nasal vaccines, meningococcal strains, synthesis schedule, meningococcal isolates, recombinant class, meningococcal vaccines, resorcinol reagent, cuvette surface, complement source, seria meningitidis
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Molecular Medicine, Humana Press Inc, New York, Becton Dickinson, Meningococcal Vaccine Trials, Outer Membrane Protein Purification, Peptide Mimics of LOS Epitopes, Immunoblot Analysis of Sera, World Health Organization, Coating Buffer, Optical Biosensor Techniques, Academic Press, Eleventh International Pathogenic Neisseria Conference, Whole-Blood Model, Mueller Hinton, San Diego, T-Cell Epitope Mapping, The Netherlands, Construction of Neisseria, New England Biolabs, Potters Bar, Meyer Ness, Difco Laboratories, Current Protocols, Sao Paulo
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