This volume features selected childhood diseases based on a variety of metabolic abnormalities: neuronal ceroid-lipofuscinosis, peroxisomal disorders, galactosemia, homocystinuria and mucolipidoses. The chapters illustrate the new insights that have recently been gained into these puzzling disorders by studies combining the traditional methods of morphology, histochemistry and electron microscopy with the newly available techniques of molecular biology. They present examples of the advances made and discuss future research directions with both traditional and molecular biological techniques. With contributions from leading specialists, the book provides general and surgical pathologists, developmental biologists, oncologists and paediatricians with convenient access to the latest findings on these uncommon genetic diseases.
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