"Recommended for most academic libraries and research collections which support research in coordination chemistry, biological inorganic chemistry, and the newer work in protein folding." (E-STREAMS, September 2007)
"This is a worthwhile contribution that should have a broad audience." (Doody's Health Services)
“…concepts are bang up-to-date by breaking research news appearing as reference notes.” (Coordination Chemistry Reviews, Dec 2006) --This text refers to an alternate Hardcover edition.
From the Back Cover
Volume 1, offers in 15 stimulating chapters an authoritative view of the fascinating research on Neurodegenerative Diseases and Metal Ions. Written by 41 internationally recognized experts, ithighlights, supported by 130 illustrations, the recent progress made in understanding the role metal ions play in diseases like transmissible spongiform encephalopathies (Creutzfeldt-Jakob and related diseases), Alzheimer's, Parkinson's, Huntington's, Wilson's and Menkes' diseases, as well as in familial amyotrophic lateral sclerosis and others. The interplay between metal ions, catecholamines and the formation of reactive oxygen species resulting in oxidative stress is considered, as is the metalloneurochemistry of zinc and the neurotoxicity of aluminum, cadmium, lead, and mercury. The need for novel drugs which manipulate metal-centered neuropathology is emphasized. With more than 2000 references this book is a vital resource for scientists and advanced students. --This text refers to an alternate Hardcover edition.