Start reading Metastasis (Novartis Foundation Symposia) on the free Kindle Reading App or on your Kindle in under a minute. Don't have a Kindle? Get your Kindle here.

Deliver to your Kindle or other device

Enter a promotion code
or gift card
 
 
 

Try it free

Sample the beginning of this book for free

Deliver to your Kindle or other device

Sorry, this item is not available in
Image not available for
Color:
Image not available

To view this video download Flash Player

 

Metastasis (Novartis Foundation Symposia) [Kindle Edition]

CIBA Foundation Symposium

Digital List Price: $175.00 What's this?
Kindle Price: $140.00
You Save: $35.00 (20%)

Free Kindle Reading App Anybody can read Kindle books—even without a Kindle device—with the FREE Kindle app for smartphones, tablets and computers.

To get the free app, enter your email address or mobile phone number.

Formats

Amazon Price New from Used from
Kindle Edition $140.00  
Hardcover --  

Book Description

An international group of researchers addresses basic mechanism involved in the metastatic spread of tumors and considers new methods of prevention and treatment. Compares behavior of normal and abnormal cells, with emphasis on cell surface mechanisms--especially invasive processes--and inhibitors that might prevent metastasis. Also discusses determination of the metastatic genotype, the role of the immune system, and reduction of metastasis via liposome-activated macrophages.

Editorial Reviews

From the Publisher

An international group of researchers addresses basic mechanism involved in the metastatic spread of tumors and considers new methods of prevention and treatment. Compares behavior of normal and abnormal cells, with emphasis on cell surface mechanisms--especially invasive processes--and inhibitors that might prevent metastasis. Also discusses determination of the metastatic genotype, the role of the immune system, and reduction of metastasis via liposome-activated macrophages.

From the Back Cover

Metastasis Chairman: I. J. Fidler 1988 Despite advances in diagnosis and treatment, cancer is still a major cause of morbidity and mortality, and metastases that are resistant to therapy remain the chief cause of death from cancer. An understanding of the basic mechanisms by which metastases are produced is required if rational antimetastatic strategies are to be developed. An international group of scientists met at the Ciba Foundation to evaluate their recent work in relation to the metastatic spread of tumours and to consider the implications for new methods of prevention and treatment. Much of the emphasis in this volume is placed on mechanisms operating at the cell surface, including the contribution of cell adhesion molecules, and of fibronectin and other extracellular matrix components, to the behaviour of normal and abnormal cells. Investigations into the role of growth factors and motility factors, and secreted enzymes such as type IV collagenase, are also providing insights into invasive processes, and inhibitors are being developed and tested for their possible use in metastasis prevention. Other studies are concentrating on the search for the genes that determine the metastatic phenotype; the results of transfecting DNA from metastatic to non-metastatic cells are discussed in the symposium. The role of the immune system, including the part played by MHC genes, is also considered. Studies of the reduction of metastases by means of liposome-activated macrophages provide hope that tumour progression and heterogeneity can be circumvented. With its emphasis on basic mechanisms and on clinical intervention, this symposium should interest cell, molecular and developmental biologists, molecular geneticists, immunologists, clinical oncologists, and other physicians concerned with new approaches to an old but persistent problem. Other Ciba Foundation Symposia: No 125 Junctional complexes of epithelial cells Chairman: Sir Michael Stoker 1986 ISBN 0 471 91091 0 No 131 Tumour necrosis factor and related cytotoxins Chairman: L. J. Old 1987 ISBN 0 471 91097 X No 134 Research and the ageing population Chairman: T. F. Williams 1988 ISBN 0 471 91420 7

Product Details

  • File Size: 5876 KB
  • Print Length: 266 pages
  • Publisher: Wiley; 1 edition (July 31, 2009)
  • Sold by: Amazon Digital Services, Inc.
  • Language: English
  • ASIN: B000SB8C9C
  • Text-to-Speech: Enabled
  • X-Ray:
  • Word Wise: Not Enabled
  • Lending: Enabled
  • Amazon Best Sellers Rank: #2,419,959 Paid in Kindle Store (See Top 100 Paid in Kindle Store)
  •  Would you like to give feedback on images?


Customer Reviews

There are no customer reviews yet.
5 star
4 star
3 star
2 star
1 star
Share your thoughts with other customers

Forums

There are no discussions about this product yet.
Be the first to discuss this product with the community.
Start a new discussion
Topic:
First post:
Prompts for sign-in
 


Look for Similar Items by Category