This volume includes a variety of methods involving electron microscopy and other biophysical methods, such as crystallography, neutron scattering, and NMR procedures for the analysis of protein-RNA or RNA-RNA interactions by cross-linking, the use of chemical, enzymatic, and immunological probes, as well as functional and genetic approaches for the study of this nucleoprotein. These methodologies will contribute to the progress toward the elucidation of the structure, function, and regulatory processes that affect this most important complex cellular component, the ribosome.
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Book Description
Editorial Reviews
Review
Praise for the Volume
"The volume is of a high scientific and technical standard usual for this series and will certainly be of great value as a basic methodological handbook to research specialists involved in biochemical, biophysical and ultrastructural ribosome analysis and related studies."
--BIOLOGIA PLANTARUM
Praise for the Series
"The Methods in Enzymology series represents the gold-standard."
--NEUROSCIENCE
"Incomparably useful."
--ANALYTICAL BIOCHEMISTRY
"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page."
--BIO/TECHNOLOGY
"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection."
--CHEMISTRY IN INDUSTRY
"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced."
--AMERICAN SOCIETY OF MICROBIOLOGY NEWS
"If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work."
--ENZYMOLOGIA
"A series that has established itself as a definitive reference for biochemists."
--JOURNAL OF CHROMATOGRAPHY
"The volume is of a high scientific and technical standard usual for this series and will certainly be of great value as a basic methodological handbook to research specialists involved in biochemical, biophysical and ultrastructural ribosome analysis and related studies."
--BIOLOGIA PLANTARUM
Praise for the Series
"The Methods in Enzymology series represents the gold-standard."
--NEUROSCIENCE
"Incomparably useful."
--ANALYTICAL BIOCHEMISTRY
"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page."
--BIO/TECHNOLOGY
"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection."
--CHEMISTRY IN INDUSTRY
"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced."
--AMERICAN SOCIETY OF MICROBIOLOGY NEWS
"If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work."
--ENZYMOLOGIA
"A series that has established itself as a definitive reference for biochemists."
--JOURNAL OF CHROMATOGRAPHY
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Inside This Book
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First Sentence:
To date, the most detailed knowledge of ribosomal morphology has been obtained by the combination of electron microscopy and single-particle averaging and three-dimensional (3-D) reconstruction methods. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
cloacin fragment, maxicell technique, tightly coupled ribosomes, antibody attachment site, colicin fragment, polylysine synthesis, tilted particle images, restriction nuclease fragments, individual ribosomal proteins, zonal run, extension inhibition analysis, tungsten wire temperature, reconstituted subunits, tritium bombardment, limited enzymatic digestion, puromycin reaction, conical tilting, ribosomal surface, erythromycin resistance mutations, reconstitution buffer, ribosomal system, kidney view, active ribosomes, asymmetric projection, ribosomal particles Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nucleic Acids Res, Academic Press, New York, Federal Republic of Germany, Cibacron Blue, Cold Spring Harbor Lab, Nucleic Acid Res, Electron Microsc, Boehringer Mannheim, University Park Press, Toyo Soda, Cell Biol, Laboratory Manual, Molecular Cloning, New England Nuclear, Protein Chemistry, Trends Biochem, American Chemical Society, Modern Methods, San Francisco, Acta Biol, National Science Foundation, Advanced Techniques, Apply Fourier, Cell Res New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
To date, the most detailed knowledge of ribosomal morphology has been obtained by the combination of electron microscopy and single-particle averaging and three-dimensional (3-D) reconstruction methods. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
cloacin fragment, maxicell technique, tightly coupled ribosomes, antibody attachment site, colicin fragment, polylysine synthesis, tilted particle images, restriction nuclease fragments, individual ribosomal proteins, zonal run, extension inhibition analysis, tungsten wire temperature, reconstituted subunits, tritium bombardment, limited enzymatic digestion, puromycin reaction, conical tilting, ribosomal surface, erythromycin resistance mutations, reconstitution buffer, ribosomal system, kidney view, active ribosomes, asymmetric projection, ribosomal particles Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nucleic Acids Res, Academic Press, New York, Federal Republic of Germany, Cibacron Blue, Cold Spring Harbor Lab, Nucleic Acid Res, Electron Microsc, Boehringer Mannheim, University Park Press, Toyo Soda, Cell Biol, Laboratory Manual, Molecular Cloning, New England Nuclear, Protein Chemistry, Trends Biochem, American Chemical Society, Modern Methods, San Francisco, Acta Biol, National Science Foundation, Advanced Techniques, Apply Fourier, Cell Res New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 36
books:
See all 36 books this book cites
- Molecular Cloning: A Laboratory Manual, Third Edition (3 volume set) by Joe Sambrook on 6 pages
- Modern Methods in Protein Chemistry by Harald Tschesche on 4 pages
- Computer Processing of Electron Microscope Images (Topics in Current Physics) by Peter W. Hawkes on page 3, page 9, and page 39
- Data Reduction and Error Analysis for The Physical Sciences by P. R. Bevington on page 128, and page 537
- Advanced Methods in Protein Microsequence Analysis by B. Wittmann-Liebold on page 544, and page 564
See all 36 books this book cites
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