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Methods in Enzymology, Voluyme 248: Proteolytic Enzymes: Aspartic and Metallo Peptidases [Hardcover]

Alan J. Barrett (Editor)


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Book Description

July 6, 1995 0121821498 978-0121821494 1
In this volume of Methods in Enzymology and its companion Volume 244, the chapters on specific methods, enzymes, and inhibitors are organized within the rational framework of the new systems for classificationand nomenclature. A wide variety of specificities of peptide bond hydrolysis are represented in each set of peptidases, together with an equally wide range of biological functions.

Key Features
* Aspartic peptidases
* Metallopeptidases
* New information on classification of proteolytic enzymes
* Medical implications of research in this area
* Biotechnological uses of these enzymes

Editorial Reviews

Review

Praise for the Volume
"Because this is a very significant and timely review, this book is a worthy contribution to any chemical, biological, or medical library for those interested not only in proteases but also their physiologic roles in matrix degradation and post-translational processing."
--DOODY'S JOURNAL
Praise for the Series
"The Methods in Enzymology series represents the gold-standard."
--NEUROSCIENCE
"Incomparably useful."
--ANALYTICAL BIOCHEMISTRY
"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page."
--BIO/TECHNOLOGY
"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection."
--CHEMISTRY IN INDUSTRY
"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced."
--AMERICAN SOCIETY OF MICROBIOLOGY NEWS
"If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work."
--ENZYMOLOGIA
"A series that has established itself as a definitive reference for biochemists."
--JOURNAL OF CHROMATOGRAPHY

Product Details

  • Hardcover: 873 pages
  • Publisher: Academic Press; 1 edition (July 6, 1995)
  • Language: English
  • ISBN-10: 0121821498
  • ISBN-13: 978-0121821494
  • Product Dimensions: 9.1 x 6 x 1.7 inches
  • Shipping Weight: 2.9 pounds
  • Amazon Best Sellers Rank: #3,646,444 in Books (See Top 100 in Books)

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Inside This Book (learn more)
First Sentence:
Synthetic peptide substrates are widely used in biochemical and physiological studies of proteolytic enzymes. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
aggrecan core protein fragments, staphylolytic activity, virus retropepsin, mammalian reproductive proteins, hemorrhagic potency, plastic depression plates, mouse meprin, venom metalloproteinases, progress curve method, other metallopeptidases, thermolysin family, aminopeptidase family, pepsin family, intermediate peptidase, hemorrhagic toxins, milk assay, hemorrhagic activity, thioester substrates, collagenase assay, peptide thioesters, astacin family, proteinase domain, thimet oligopeptidase, methionyl aminopeptidase, pig pepsin
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Van Wart, Academic Press, New York, Nucleic Acids Res, Cell Biol, National Institutes of Health, Brain Res, Reagents Buffer, Trends Biochem, Gustav Fischer, Prompted Constant, Protein Res, Ser Pro Npa Arg Mep, Tissue Res, Matrix Suppl, Oral Biol, Protein Chem, Reagents Substrate, Riot Chem, Variable Name, Acknowledgments Work, Blue Sepharose, Boca Raton, C-terminal Arg, Costa Mesa
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