Microarray Analysis [Hardcover]

Mark Schena (Author)

Book Description

ISBN-10: 0471414433 | ISBN-13: 978-0471414438 | Publication Date: November 11, 2002 | Edition: 1

This authoritative text begins with an introduction to basic microarray technology. The author then provides clear explanations of the conceptual and theoretical basis of this technology, followed by thorough and multi-disciplinary coverage of modern and emerging applications. The coverageincludes chapters on microarray informatics, gene expression profiling, genetic diagnostics, and novel microarray technologies.

Editorial Reviews

Review

"…ideal for those who are interested in a broad introduction to microarrays, one that describes thing literally from the ground up." (American Journal of Physical Anthropology, August 2004)

"…a valuable addition to the…series…I enjoyed reading the text, as it has been written in an entertaining way, and I strongly recommend the book to everyone interested in this fascinating new field." (Angewandte Chemie International Edition, 2004/43)

"…a rigorous but reader-friendly critique of diverse ways that genome data can be used in academic and industrial research…" (Genetic Engineering News, Vol. 23, No. 13, July 2003)

"...an essential resource for anyone involved in the life sciences...the first textbook treatment of this innovative technique..." (Word Trade)

"...an essential resource for anyone involved in the life sciences...the first textbook treatment of this innovative technique..." (Word Trade)

"...an excellent text...a valuable reference.... If you need to know what microarrays are, how they can be used, how they work, and how you can analyze the data...then this book will provide the insight." (Clinical Chemistry, Vol. 49, No. 6, 2003)

"...a very personal, encyclopedic, diffuse compendium of everything known about microarrays...fun to read...full of information that a working biologist...might be quite interested to learn." (ASM News, Vol. 69, No. 7, 2003)

"...the book is highly recommended as an excellent one stop resource on microarray technology." (Proteomics, October 2003)

From the Author

Microarray analysis is revolutionizing medicine, agriculture and the basic and clinical sciences, and has spawned a multi-billion dollar commercial enterprise. This high-tech blend of biology and technology is unraveling the mysteries of the human genome, and is expediting the development of safer drugs and new genetic tests. Microarray Analysis is an essential textbook for anyone in the Life Sciences.

See all Editorial Reviews

Product Details

• Hardcover: 664 pages
• Publisher: Wiley-Liss; 1 edition (November 11, 2002)
• Language: English
• ISBN-10: 0471414433
• ISBN-13: 978-0471414438
• Product Dimensions: 10.8 x 9.1 x 1.4 inches
• Shipping Weight: 3.8 pounds (View shipping rates and policies)
• Average Customer Review: 4.4 out of 5 stars  See all reviews (8 customer reviews)
• Amazon Best Sellers Rank: #1,426,409 in Books (See Top 100 in Books)

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Customer Reviews

Most Helpful Customer Reviews

10 of 10 people found the following review helpful:

4.0 out of 5 stars The other reviewer is right about the misleading title, September 10, 2005

By 

Mike_brazil "Michael" (Rockville, MD) - See all my reviews

This review is from: Microarray Analysis (Hardcover)

Despite the fact that this book has very little about microarray data analysis, it is still a very good book about microarray technology. The author even introduces the reader to the basic organic chemistry and the physics necessary for fully understanding what is a microarray and how it works. The book has many interesting information which I did not see in other similar books and which can help you create the necessary microarray culture you will need. On the other hand, the book does not provide protocols or detailed methods for your experiments (if you are looking for something like this you will need the "DNA MICROARRAYS: A Molecular cloning manual" which is some kind of Maniatis of the microarrays).

In relation to data analysis this book does not provide you with even the basics for analysing your data, which is a fairly complex task. If you need help with that (and you are a biologist) I would suggest "Data analysis tools for DNA Microarrays" by Sorin Draghici, which is a very good intro book to data analysis and is not too hard on the math side (actually it is as simple as possible but without oversimplifying it). If you are a math person than you might prefer Terry Speed's "Statistical Analysis of Gene Expression Microarray Data" or Cabrera's "Exploration and Analysis of DNA Microarray and Protein Array Data".

16 of 19 people found the following review helpful:

1.0 out of 5 stars Microarray Analysis is a misleading title, May 23, 2003

By 

David (Emeryville, CA) - See all my reviews

This review is from: Microarray Analysis (Hardcover)

This book by Schena is not analytical in the rigourous sense. No mathematical methods are discussed other than in passing. Rather it is wide ranging, unfocused and occasionally comical. For example Schena begins the Preface with absurdly off topic quotes from Picasso and Neitzche and name drops throughout. Schena (or his publisher) even claims to be the "Father of Microarray Technology": a bold title that properly is shared between Patrick Brown and Steve Fodor. Schena digresses into such irrelevancies as defining the Internet and the value of Venture Capital. The book is quite uneven, it goes in depth on the specific chemical issues relevent to cDNA arrays and is very shallow on normalization clustering and stat. level analysis. I found the book entertaining, but I doubt that was Authors intent. Also I should note I was given the book as a gift. I can't imagine paying for it.

4 of 6 people found the following review helpful:

5.0 out of 5 stars A grand introduction to a daunting field, July 1, 2003

By 

Martin T Baker (Petaluma, CA USA) - See all my reviews

This review is from: Microarray Analysis (Hardcover)

As an emerging discipline, Microarray analysis is somewhat overwhelming and this book provides an excellent overview and introduction. While it does not give the reader the ability to perform high level data analysis, it certainly provides the criteria which would be necessary to design one. I personally rather enjoyed the casual and light hearted editaorial handling of what could have been a very dry text. I am an engineer, interested in the techniques of Microarray analysis more than the actual execution, but even I found the book extremely valuable. An excellent introductory and intermediate text. Readable by and valuable to almost anyone with a basic background in and understanfding of the life sciences. Extraordinary and a great addition to any library!