The medical mystery Misconception by Avner Hershlag has been published by iUniverse, Inc. While science fiction in medicine has been rampant, this new novel stands along with giant medical thrillers such as Sinclair Lewis' Arrowsmith, Camus' The Plague, and the more recent best seller by Abraham Verghese, Cutting for Stone, which detail the angst of the ethical physician caught in medical mystery.
Hershlag, himself a world class obstetrician and fertility expert, brings a master's understanding of the magnificence of fertilization, embryogenesis and conception to the reader. What sounds like science fiction occurs every day in his laboratory, which allows couples struggling with infertility to proceed successfully to have healthy children. His is a world of helplessness followed by the hope and happiness which is so beautifully detailed in a wonderful letter to his protagonist, a young and brilliant fertility specialist Dr. Anya Krim, from triplets born to an infertile mother in which we read "Thank you, Dr. Krim, for not giving up on our mommy. Had it not been for you, we wouldn't have come to this world." This letter tells of the joy and glory of this field. We are, however, treated to the angst of this specialty as well, including the constant concern about assuring the preservation of embryos whose lives depend on the continuous replenishment of liquid nitrogen in the freezers, the reliability of electricity and the assumption that there will be no tampering with such refrigerators by trusted employees.
In this strange test tube world, Hershlag weaves a fantastic mystery of an evil genetically disabled infertile man with Fragile "Y" syndrome who dabbles in the world of cellular cloning of animals and humans and in the world of infertility for nefarious purposes. Here, in this world, a brilliant but less talented young physician who is unable to properly care for human embryos is perverted into the conniving world of a megalomaniacal business man to carry out human cloning and embryo implantations for monetary gain.
Hershlag gives us the far more talented, deeply committed, staunchly honest and ethical Dr. Krim, who slowly unravels a thrilling mystery that carries us into the world of stem cell biology using embryos, contraception ethics and government oversight of a woman's right to have children and to have them made in test tubes. We are thrust into a world where the preservation of life in the infertile mother is looked at so differently than in the ordinary discussion of the pro and anti-abortion world. So many new issues are raised in this book about life in general that this novel stands as a wonderful beginning for any philosophical discussion about what is actually life. In the frozen world of a liquid nitrogen freezer exists happiness for the infertile couple, life to so many future Einsteins or Beethovens, carpenters or cooks. There exists health for patients with irreversibly damaged kidneys or livers and for brittle diabetics awaiting transplantation of islet cells, and for burn victims needing healthy skin. This world, so protected by Dr. Krim and so threatened by outside forces, provides the backdrop for Hershlag's genetic mystery.
Hershlag aptly gives the reader the genetic background to appreciate the complexity of the DNA world, while captivating the reader with a work that cannot be put down until the mystery is solved. This book reads with compelling speed as the story evolves. It is a must for any physician, for the ethicist, for the molecular biologist and for any couple who has tried to have children. It is also a wonderful mystery for the general reader with features as startling as the horse's head in Puzo's Godfather and the discussion of the ethical dilemma of the doctor in Camus' The Plague. The wonder of Hershlag's world is transmitted to the reader and brings his emotional world into our being. His is a world of trust, wonderment and joy, which requires the highest of ethical commitment to his patients coupled with the greatest of scientific skill. This book should be read by all medical students, nurses and health care workers who would best emulate the courage and ethics of Hershlag's remarkable Dr. Anya Krim. This is much more than a summer read. It is a read which raises so many issues of our modern world while providing a unique outlook of a dedicated physician with the strongest of moral intent. We are lucky to have Hershlag and his Anya Krim.