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Mitochondria [Hardcover]

Immo E. Scheffler (Author)
4.0 out of 5 stars  See all reviews (3 customer reviews)

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Book Description

July 5, 1999 0471194220 978-0471194224 1
Mitochondria are complex organelles, possessing inner and outer membranes and even their own DNA. A typical cell contains 800 mitochondria, termed the "powerhouse of the cell", playing a central role in metabolism, respiration, and ATP production. Mitochondria is the first modern, truly comprehensive authored book which tackles the biochemistry, genetics, and pathology of mitochondria in different organisms.

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Editorial Reviews

Review

"...very valuable, [...] I doubt that anyone could have done better." (Journal American Aging Association, Vol 23, 2000)

"...it is up-to-date, remarkably comprehensive yet concise and contains something for everyone...a wide range of 'Cell Biologists' will find this book valuable." (Cell Biology International, 24th August, 2000)

"...a broadly conceived and lively account of mitochondrial biology and biochemistry...not written to be a textbook but, because he writes with such clarity and spark, and...in such an organized and complete manner...it would serve very well as a...text." (Biochemistry and Molecular Biology Education, Vol. 29, 2001)

From the Back Cover

Praise for the First Edition

"Very valuable."
Journal of the American Aging Association

"Remarkably comprehensive yet concise and contains something for everyone . . . a wide range of 'Cell Biologists' will find this book valuable."
Cell Biology International

"A broadly conceived and lively account of mitochondrial biology and biochemistry . . . [written] with such clarity and spark, and in such an organized and complete manner."
Biochemistry and Molecular Biology Education

This book is the eagerly awaited Second Edition of the bestselling book widely acknowledged as the first modern, truly comprehensive work on mitochondria.

Mitochondria, Second Edition brings readers up to date on the many significant findings that have occurred since the book was first published nearly a decade ago. As in that seminal first edition, this Second Edition tackles the biochemistry, genetics, and pathology of mitochondria in different organisms. The growth of the subject has required more emphasis on mammalian mitochondria, but fundamental new insights from other organisms are also included. The new edition provides thorough updates of all the literature concerning this vital organelle, its functions, ongoing research surrounding it, and its importance vis-à-vis a broad range of issues in cellular and molecular biology. Mitochondria, Second Edition includes detailed descriptions of current and developing technologies involved in mitochondrial research and discovery, and highlights subjects that are growing, such as the use of proteomics.

Complete with black-and-white drawings and photographs, Mitochondria, Second Edition is an invaluable resource for all geneticists, biologists, and educators in the life sciences. It is also of interest to advanced students in genetics and molecular biology.


Product Details

  • Hardcover: 392 pages
  • Publisher: Wiley-Liss; 1 edition (July 5, 1999)
  • Language: English
  • ISBN-10: 0471194220
  • ISBN-13: 978-0471194224
  • Product Dimensions: 9.5 x 6.2 x 0.9 inches
  • Shipping Weight: 1.5 pounds (View shipping rates and policies)
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (3 customer reviews)
  • Amazon Best Sellers Rank: #2,546,810 in Books (See Top 100 in Books)

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6 of 6 people found the following review helpful:
4.0 out of 5 stars Great book for scientists who need a start "getting to know mitochondria", June 26, 2010
One person in my lab said: "How can one scientist know so much about mitochondria?"
Readable for the college/graduate/first year medical student. A superb mid-level introduction. Could have slightly more biophysical treatment of protonmotive forces/membrane potential. All in all, the book chosen for graduate students entering the lab.
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3 of 3 people found the following review helpful:
5.0 out of 5 stars fascinating, November 9, 2010
By 
Stephen Pellerine (In a bookshelf somewhere) - See all my reviews
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As a non specialist I am very interested in cell biology and am especially interested in the Mitochondria as per its role in oxidative phosphorylation. It is interesting from a sports physiology perspective. It also has sections on diseases which are now being researched more than ever (AZ, Parkinson's) and these sections provide a brief background on such diseases and their connection to the mitochondria. This book is fascinating and makes for a good companion to Lane's, Power, Sex, and Suicide. If new to this area Lane's is a easier first read. I think that for an average person, with a very keen interest in the cell, the book provides as a challenging yet fascinating read.
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2 of 2 people found the following review helpful:
3.0 out of 5 stars Difficult to read, January 1, 2011
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I admire the concept of one person trying to cover such a comprehensive subject and there is a lot of good information contained in this book, but it is very difficult to read. You have to go back again and again to try and figure out what he is trying to say. Reminded me of some of my poor quality books in graduate school.

I am not making this comment lightly, I know how difficult good scientific writing is. I wish more people would attempt books like this.

Fascinating subject!
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Inside This Book (learn more)
First Sentence:
A review by Cowdry in 1918, quoted by Lehninger [1], contains more than a dozen terms referring to structures we now identify as mitochondria: blepharoblasts, chondriokonts, chondriomites, chondrioplasts, chondriosomes, chomdriospheres, fila, fuchsinophilic granules, Korner, Fadenkorper, mitogel, parasabal bodies, plasmasomes, plastochondria, plastosomes, vermicules, sarcosomes, interstitial bodies, bioblasts, and so on. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
nit genome, pet mutants, mammalian complex, mitochondrial fusions, proton leakage, vertebrate mitochondria, translational activators, mitochondrial protein synthesis, mitochondrial extracts, chemiosmotic hypothesis, mitochondrial gene expression, protein import, matrix side, plant mitochondria, coupled mitochondria, mitochondrial morphology, nonfermentable carbon sources, bongkrekic acid, nuclear mutations, replicative advantage, endosymbiont hypothesis, mitochondrial mutations, polycistronic transcripts, anchor proteins, animal mitochondria
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Cell Biol, Academic Press, Cell Genet, Methods Enzvmol, Nature Genet, Raven Press, Cold Spring Harbor Press, Kluwer Academic Publishers, San Diego, South America, Van Hellemond, Von Jagow, Bering Strait, Methods Enzymol, Van Raaij, Basis Dis, Boca Raton, Cell Mol, Human Pathology, North America, Nucleic Acids Res, Plant Mol, Rockefeller Institute, Trends Genet
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