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The Molecular Biology of Cancer [Paperback]

Michael Khan (Editor), Stella Pelengaris (Editor)
5.0 out of 5 stars  See all reviews (1 customer review)

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Book Description

February 28, 2006 1405118148 978-1405118149 1
This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer.
  • Written by an international panel of researchers, specialists and practitioners in the field
  • Covers both traditional areas of study and areas of controversy and emerging importance, highlighting future directions for research
  • Features up-to-date coverage of recent studies and discoveries, as well as a solid grounding in the key concepts in the field
  • Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review
  • Supported by a dedicated website at www.blackwellpublishing.com/pelengaris
  • An excellent text for upper-level courses in the biology of cancer, for medical students and qualified practitioners preparing for higher exams, and for researchers and teachers in the field

  • Frequently Bought Together

    The Molecular Biology of Cancer + Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics + The Biology of Cancer
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    Editorial Reviews

    Review

    “The explosion of information on the molecular biology of cancer, and its widespread and immediate availability via the internet, provides major challenges for those engaged in cancer treatment and research. A single up-to-date reference textbook on this topic is needed more than ever. This book will go a long way towards meeting this need, providing a valuable resource for a range of individuals and departments.”
    Stan Kaye, Royal Marsden Hospital, London

    “Pelengaris, Khan, and the contributing authors are to be applauded. The Molecular Biology of Cancer is a comprehensive and readable presentation of the many faces of cancer from molecular mechanisms to clinical therapies and diagnostics. This book will be welcomed by neophyte students, established scientists in other fields, and curious physicians.”
    Dean Felsher, Stanford University

    "This book deserves great praise for the readable presentation of this complex field." Molecular Cancer, November 2007

    From the Back Cover

    This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer. The text offers in-depth coverage of traditional areas of study, while also discussing areas of controversy and emerging importance and highlighting future directions for research.


    Common cancers such as lung, breast, colon and skin cancer are used to illustrate key concepts and fundamental biological processes throughout the text. In addition, each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review. Offering up-to-date coverage of recent studies and discoveries, as well as a solid grounding in the key concepts in the field, this book will be an excellent text for upper-level courses in the biology of cancer, for medical students and qualified practitioners preparing for higher exams, and for researchers and teachers in the field.


    Product Details

    • Paperback: 544 pages
    • Publisher: Wiley-Blackwell; 1 edition (February 28, 2006)
    • Language: English
    • ISBN-10: 1405118148
    • ISBN-13: 978-1405118149
    • Product Dimensions: 9.6 x 7.4 x 1.3 inches
    • Shipping Weight: 2.9 pounds (View shipping rates and policies)
    • Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
    • Amazon Best Sellers Rank: #337,036 in Books (See Top 100 in Books)

     

    Customer Reviews

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    10 of 10 people found the following review helpful:
    5.0 out of 5 stars Complete and Well Written, June 7, 2006
    This review is from: The Molecular Biology of Cancer (Paperback)
    There are any number of books on cancer from little phamplets for the new patient to heavy duty books that summarize the current research going on in specialized areas.

    This book is aimed at the advanced undergraduate or beginning graduate student with some background in biology. It covers cancer from nearly every aspect. It begins with a general introduction to cancer and its impact from around the world. It goes on to cover the current state of research in every significant area. The writers are a who's who of cancer researchers, where each major subject area is written by a specialist in that area.

    The editors are researchers in their own right. They jointly run the cancer research group at the University of Warwick which has produced significant findings. For a book written in this manner, this book is surprisingly well written and understandable. This is the job of a good editor and they have done it well.
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    Inside This Book (learn more)
    First Sentence:
    In general cancers begin with a mutational event in a single cell and then develop in multiple stages through the acquisition of further mutations that are inherited by the progeny of that cell when it divides - cancer is a clonal disease (Fig. 1.2). Read the first page
    Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
    oncogene collaboration, omic instability, executioner procaspases, oncogenic stress, hyperproliferative signals, tumor reversal, cell cycle engine, telomere attrition, cell cycle entry, brief inactivation, caretaker genes, oncogenic lesion, island microarrays, dysfunctional telomeres, telomere capping, inducing growth arrest, tumor maintenance, motile machinery, mural cells, critically short telomeres, cell cycle exit, telomere dysfunction, adoptive therapy, unattached kinetochores, senescent cells
    Key Phrases - Capitalized Phrases (CAPs): (learn more)
    United States, United Kingdom, National Academy of Sciences, New England, Nature Genetics, British Medical, Molecular Cell Biology, Lancet Oncology, Nature Medicine, New York, Oxford University Press, Active Inactive, Bruce Ames, Erythroblastosis Deregulated, Leland Hartwell, Nat Rev Cancer, Nature Biotechnology, Nature Cell Biology, World Health Organization, Chromosomal Syndrome Cloned, Current Biology, Current Opinion, Cyclin-dependent Cell, Genes Development, Genotype Phenotype
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