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Molecular Biology of the Cell [Hardcover]

Bruce Alberts , Alexander Johnson , Julian Lewis , Martin Raff , Keith Roberts , Peter Walter
4.6 out of 5 stars  See all reviews (218 customer reviews)

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Book Description

November 16, 2007 0815341059 978-0815341055 5

For nearly a quarter century Molecular Biology of the Cell has been the leading cell biology textbook. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advancing understanding of cell biology. To list but a few examples, a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); and cell cycle control and the mechanics of M phase (now integrated into one chapter).

The hallmark features of Molecular Biology of the Cell have been retained, such as its consistent and comprehensive art program, clear concept headings, and succinct section summaries. Additionally, in response to extensive feedback from readers, the Fifth Edition now includes several new features.

It is now more portable. Chapters 1-20 are printed and Chapters 21-25, covering multicellular systems, are provided as PDF files on the free Media DVD-ROM which accompanies the book.* And for the first time, Molecular Biology of the Cell now contains end-of-chapter questions. These problems, written by John Wilson and Tim Hunt, emphasize a quantitative approach and the art of reasoning from experiments, and they will help students review and extend their knowledge derived from reading the textbook. The Media DVD-ROM, which is packaged with every copy of the book, contains PowerPoint® presentations with all of the figures, tables and micrographs from the text (available as JPEGs too). Also included is the Media Player, which plays over 125 movies—animations, videos, and molecular models—all with voice-over narration. A new reader-friendly feature is the integration of media codes throughout the text that link directly to relevant videos and animations. The Media DVD-ROM holds the multicellular systems chapters (21-25) of the text as well.

By skillfully extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and thereby create a coherent framework through which readers may approach and enjoy this subject that is so central to all of biology.

* There is also a reference edition of Molecular Biology of the Cell, Fifth Edition (ISBN 978-0-8153-4111-6) that contains Chapters 1-25 entirely in printed format.


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Molecular Biology of the Cell + Molecular Biology of the Cell, Fifth Edition: The Problems Book
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Editorial Reviews

Review

"Throughout the book, emphasis is placed not just on what 'we know' but also on 'how we know' and 'what remains to be discovered'- important for engaging and enthusing students....A quarter of a century after the first edition revolutionised cell biology textbooks, the new edition is as fresh, comprehensive and above all, as readable as ever....Like its predecessors, this is a superb textbook for advanced undergraduate and postgraduate students."

-British Society for Developmental Biology Newsletter, Summer 2008, Vol. 29, No. 1

"Professors, lecturers, and instructors will find the fifth edition of the book Molecular Biology of the Cell and its accompanying Problems Book to be an excellent choice for guiding their students through the maze of the cell's molecular structures and biochemical processes....With countless colorful illustrations and a large number of photographs and tables, reading the text becomes not only an educational experience, but also a highly enjoyable one for those students who wish to discover the inner workings of the magnificent cellular machine....Educators will also find the DVD-ROM to be a rich electronic resource when compiling their lectures....No less important is the Problems Book, which contains numerous exercises and questions that are an integral part of the learning process, and that teachers, instructors, and students are sure to appreciate."

The Quarterly Review of Biology, September 2008, Volume 83, Number 3

 

"It has been 25 years since the first edition of Molecular Biology of the Cell (MBoC) was published, which means that roughly half of today's practicing scientists do not remember life without this cell biology `bible'. The other half might recall how the book almost instantly filled a void with refreshingly clear and engaging writing illustrated with extensive diagrams and figures….MBoC has only improved over its several editions, growing with the rapid advances in the field to become an essential resource for students at all levels and a trusted first stop for researchers transitioning into unfamiliar areas of cell biology….An enduring strength of the book is that it remains a comprehensive textbook….In addition to the comprehensive updating of every chapter, another reason to consider acquiring edition five is the improved integration of the print volume with an extensive array of videos and animations in the `Cell Biology Interactive' provided on the accompanying DVD….Another welcome improvement in MBoC5 helps link the textbook to the lab - there are now problems printed at the ends of the first 20 chapters. Whereas some are designed to facilitate information retention, the best problems stimulate thought and challenge the reader to think about experimental approaches for learning new things about cell biology….the MBoC5 package is a fantastic resource and well worth the upgrade."

-Development (Company of Biologists) 135, 3973-3974 (2008)

 

"[Molecular Biology of the Cell] is a marvelous textbook. Once again, the authors are to be congratulated on a superb achievement. We are amazed at the scope and depth of information provided.”
- Bioscience Education

About the Author

Bruce Alberts received his PhD from Harvard University and is Professor of Biochemistry and Biophysics at the University of California, San Francisco. For 12 years, he served as President of the U.S. National Academy of Sciences (1993-2005).

Alexander Johnson received his PhD from Harvard University and is Professor of Microbiology and Immunology and Director of the Biochemistry, Cell Biology, Genetics, and Developmental Biology Graduate Program at the University of California, San Francisco.

Julian Lewis received his DPhil from the University of Oxford and is a Principal Scientist at the London Research Institute of Cancer Research UK.

Martin Raff received his MD from McGill University and is at the Medical Research Council Laboratory for Molecular Cell Biology and the Biology Department at University College London.

Keith Roberts received his PhD from the University of Cambridge and is Emeritus Fellow at the John Innes Centre, Norwich.

Peter Walter received his PhD from The Rockefeller University in New York and is Professor and Chairman of the Department of Biochemistry and Biophysics at the University of California, San Francisco, and an Investigator of the Howard Hughes Medical Institute.


Product Details

  • Hardcover: 1392 pages
  • Publisher: Garland Science; 5 edition (November 16, 2007)
  • Language: English
  • ISBN-10: 0815341059
  • ISBN-13: 978-0815341055
  • Product Dimensions: 11 x 8.7 x 1.9 inches
  • Shipping Weight: 6.7 pounds (View shipping rates and policies)
  • Average Customer Review: 4.6 out of 5 stars  See all reviews (218 customer reviews)
  • Amazon Best Sellers Rank: #6,755 in Books (See Top 100 in Books)

Customer Reviews

Most Helpful Customer Reviews
196 of 201 people found the following review helpful
5.0 out of 5 stars CD contents are worth hundreds of dollars June 1, 2002
Format:Hardcover|Verified Purchase
I'm an amateur biologist, and a professional computer software engineer and product reviewer. A keen interest in the mechanics of genetic expression has drawn me to the beautiful details of cellular mechanics. While this book is everything the other reviewers say (and are qualified to say) it is, let me weigh in on the accompanying CD, which is an area in which I can claim some expertise.
The vast majority of CDs bundled with textbooks are afterthoughts -- either an electronic copy of the text, or some lightly related adjunct materials, usually pulled from the public domain. MBotC is different. The CD is nothing short of breathtaking. A technical tour de force, this CD runs on both Mac and Windows, which is no mean feat. It leverages time-tested technologies such as Netscape, Java, and Quicktime to produce stunningly vivid presentations. It performs well, and is rock-solid stable.

Beyond flawless delivery, the content itself is brilliantly executed. This is largely original content developed for this book, and tied directly into the text chapter by chapter. You get narrated animations that show dozens of cellular processes in a way that catalyzes learning. Videos capture live microscopy showing ATP synthase rotors spinning, microtubules self-assembling, actin crawling, and mitosis mitoting. An image magnifier lets you browse photomicrographs in detail.
Most astounding of all is the seamless incorporation of a molecular viewer, the Chime Java browser plugin, which directly reads and interprets Protein Data Base (PDB) files and displays the models in interactive 3D. The CD includes hundreds of PDB models, including a wonderful reference library of amino acids, nucleotimes, lipids, and sugars.
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64 of 65 people found the following review helpful
5.0 out of 5 stars Comprehensible by Non-Specialist September 16, 2009
Format:Hardcover|Verified Purchase
[Reviewing 5th Edition, Chapters 1-7] I'm a Ph.D. computer scientist working on an NIH grant in text mining biomedical literature, so I thought I should bone up on the underlying science. The first seven chapters of this book are just what I needed. The first overview chapter is an excellent standalone introduction to the cell and genomics/proteomics and their ilk. After a two-chapter very comprehensible introduction to biochemistry (strong emphasis on thermodynamics/energy and bonding/structure) and protein structures, the next chapters lay out the entire process from DNA to protein, including expression control.

It's slow reading (it takes me an hour or more to read 10 pages), but very clearly written, and very thorough. The diagrams and accompanying text are amazingly clear and helpful. (There are also animations, but I've never looked at the DVD.) The diagrams and their long captions are often supplementary in that they add details that are not in the body of the text.

I had read the same sections of the 4th Edition a few years ago. The 5th edition adds substantial new material starting with the chapter on proteins. Ironically, the 5th edition is more speculative, because the more we find out about gene expression, the further away full understanding seems to be. The book does a nice job of balancing what's known fairly certainly with speculative guesses about things like chromatin structure.

This time, I think I'll keep going. The sections of the rest of the book I've browsed when they've been cross-referenced are also excellent.
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64 of 65 people found the following review helpful
4.0 out of 5 stars Great, but Last 5 Chapters are Electronic January 12, 2008
Format:Hardcover
GREAT book, but the only problem is that the last 5 chapters are in PDF format on an attached CD rather than in print (they did this to make the book more portable). If you want the full print version, buy the Reference edition.
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71 of 74 people found the following review helpful
5.0 out of 5 stars They keep getting better August 24, 2003
Format:Hardcover|Verified Purchase
In the past few years quite a few books on molecular biology and genetics have appeared, and all of these have been exceptionally well-written. Most have been updates of previous editions, and if compared with these, the most recent editions have displayed an enthusiasm and excitement that dwarfs their earlier editions. This book, now in its fourth edition, is an example of one of these, and I believe the reason for their increasing quality is the excitement that biologists are now feeling. This is due no doubt to the incredible strides that have been taken in biology in the last few years. Biologists are with complete justification very excited that they understand in greater detail what life is all about, and are looking forward to an even deeper understanding in the decades ahead.
As a non-biologist but one deeply embedded in bioinformatics and certain areas of computational biology, this book served my need to understand in greater detail the underlying biology behind these fields. It is a beautiful book, both from an aesthetic viewpoint and because of its content. The book reads more like a story than a textbook, but the information gain when reading it is considerable, with less entropy than what might be expected from such a deep subject with myriads of terms that must be understood before moving on to others. The author's approach to the book is well-organized, with many accompanying diagrams that illustrate the complicated processes and structures that can occur in the molecular realm. In addition, helpful summaries are put at several places in the book. There are no exercises in this book but there is a workbook that one can purchase separately.
Space prohibits a detailed review of such a large book, but some of the more interesting discussions in the book include: 1.
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Most Recent Customer Reviews
5.0 out of 5 stars Model Amazon Seller
Great! Item was delivered quickly and was as described.
Published 16 hours ago by A.Jeffrey
5.0 out of 5 stars A bit pricey, but worth it!!
THE essential text of cellular biology for anyone in the biological sciences!!! I would highly recommend the companion solutions/study manual that accompanies the text. Read more
Published 19 hours ago by NH
4.0 out of 5 stars Four Stars
good
Published 1 day ago by Hannah
4.0 out of 5 stars check your library first
note to college students: check your school's biology library to see if they have a copy of the book you can check out/use. Read more
Published 15 days ago by ilikescrambledeggs
5.0 out of 5 stars Great textbook
Good book. Clear explanations. I used this for 2 different classes: molecular biology and then cell biology. Read more
Published 1 month ago by LJ
5.0 out of 5 stars Excelent book!
This is an excelent book and i think that all medical doctors that do clincal investigation have to have into the library.
Published 1 month ago by Fernando Amador Mos
5.0 out of 5 stars Amazing book
It fulfilled all my expectations, very easy to read and understand. It is very complete (in terms of content). Loved it
Published 1 month ago by Julieta
1.0 out of 5 stars So my copy did not come with the cd. ...
So my copy did not come with the cd. Which I didn't notice until I couldn't find the last 5 chapters!! This is ridiculous.
Published 2 months ago by Faithiy
5.0 out of 5 stars Excellent Textbook
As a biologist I found this book to be an exceptional learning tool. I highly recommend this textbook to anyone who would like a deep understanding of molecular biology. Read more
Published 2 months ago by SomeGuy
5.0 out of 5 stars I love it
I've bought about six of this volume for my friends. Obviously I like it very much.blah blah blah blah bllah.
Published 2 months ago by roger warren
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