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Molecular Biology of the Cell, Fourth Edition Hardcover – March 1, 2002

ISBN-13: 978-0815332183 ISBN-10: 0815332181 Edition: 4th

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Product Details

  • Series: Molecular Biology of the Cell
  • Hardcover: 1616 pages
  • Publisher: Garland Science; 4 edition (March 2002)
  • Language: English
  • ISBN-10: 0815332181
  • ISBN-13: 978-0815332183
  • Product Dimensions: 11 x 8.8 x 2.1 inches
  • Shipping Weight: 7.4 pounds
  • Average Customer Review: 4.6 out of 5 stars  See all reviews (222 customer reviews)
  • Amazon Best Sellers Rank: #14,307 in Books (See Top 100 in Books)

Editorial Reviews

Review

"In an era when we are drowning in information, the job of a textbook such as Molecular Biology of the Cell is to help teach its readers how to swim. This it does admirably, and the punctilious attention to detail and effort devoted by the authors to covering this huge field in a lucid and easy-to-read style shines though on every page... the fourth edition of Molecular Biology of the Cell is an outstanding textbook... The clear and concise style and copious informative diagrams and illustrations set an impressive standard, and the comprehensive coverage of the field that has been achieved is quite remarkable." - Nature

 

"The book is extremely well written... The hundreds of schematic/explanatory diagrams and light and electron micrographs and the way they are integrated into the text are superb... This 4th edition will be warmly welcomed by college and university teachers, researchers and students alike. It maintains and improves upon the quality and excellence of previous editions." - Doody's Reviews

 

"The 4th edition of the Molecular Biology of the Cell does an excellent job of reporting our progress, and the next generation of purchasers should not regret the presence of this text on their bookshelves." - Cell

 

"... what is to be said about the fourth edition of Molecular Biology of the Cell? The most casual glance confirms that standards have not slipped: short subsections with informative headings, highlighted key words, italicised chapter summaries and diagrams of great clarity... it should be remembered that Molecular Biology of the Cell set the precedent of providing a substantial problems book, and Tim Hunt and John Wilson have contributed a revised version of this supplement for the fourth edition... the sheer scale of coverage by the fourth edition of Molecular Biology of the Cell means it will be the first thing most of us will reach for in pursuit of the facts of life." - Journal of Cell Science

 

"... a new kind of encyclopedia is taking shape, and for a new kind of audience. They don't just make an up-to-date alphabetical tour of some circumscribed area of human knowledge; They also try to put all that knowledge in context. The best I've yet encountered is a Molecular Biology of the Cell... It's essentially a single 1,500-plus-page essay on the microcosm that lurks invisibly at the very roots of the tree of life... the authors digest their material so brilliantly one can--with patience and a decent high-school science education--actually read the damn thing... [the] authors have with each edition improved every aspect of the book, polishing its plain, transparent prose, clarifying descriptions, enhancing illustrations... It's an easy book to like, too..." - Seattle Weekly

 

"Molecular Biology of the Cell, a hefty tome written for a wide range of students, as well as scientists wishing to follow the rapid progress in their specialized fields, delivers on its promise to give readers the most comprehensive text possible. At first glance, it doesn't seem possible that the authors had to decide what details to leave out. It looks as if they'd covered it all. From a basic discussion of cells, genomes, and cell chemistry to DNA, cellular organization, function and cell immunity, the authors have incorporated facts, specific examples, and essential concepts in a way that makes this new edition a landmark work in the field of molecular cell biology. As genomics expands more rapidly than anyone thought possible, and complete sequencing of genomes from bacteria to humans has revolutionized our understanding of living things, new information is critical. Included in this amazing text are discussions of new discoveries in biotechnology, cellular mechanisms, infection and immunity. Without sacrificing content, the authors have put together a remarkable book that can be used for courses in cell biology or molecular biology (chapters 1 through 8). Outstanding drawings, photographs, and diagrams fill the chapters to enhance the excellent writing. Every instructor will want to keep a reference copy on his or her shelf, whether they use the book for their classes or not. As a textbook, there's not one better. Highly recommended for academic libraries, as well as undergraduate, and graduate courses." - Life Science Book Review

 

Praise for the previous editions:

"The epitome of what a current upper level textbook in cell biology should be."

Quarterly Review of Cell Biology

"Accessible and relatively easy to read... timely and accurate... profusely and beautifully illustrated."

American Society for Microbiology News

"A reliable, accurate and up-to-date textbook for which students and researchers must be grateful."

Trends in Biochemical Sciences

"A big, beautiful (now in color), up-to-date survey of cell biology."

Sci Tech Book News

"The authors and their publisher have once again led the way and set the standard against which other scientific textbooks will be measured."

Biochemical Education


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Customer Reviews

The diagrams and accompanying text are amazingly clear and helpful.
Bob Carpenter
It is well written, with complete explinations and in an easy to understand language.
Katie
We used this book as both my Cell Biology text and my Molecular Genetics text.
biologybrain

Most Helpful Customer Reviews

199 of 204 people found the following review helpful By Mel Beckman on June 1, 2002
Format: Hardcover Verified Purchase
I'm an amateur biologist, and a professional computer software engineer and product reviewer. A keen interest in the mechanics of genetic expression has drawn me to the beautiful details of cellular mechanics. While this book is everything the other reviewers say (and are qualified to say) it is, let me weigh in on the accompanying CD, which is an area in which I can claim some expertise.
The vast majority of CDs bundled with textbooks are afterthoughts -- either an electronic copy of the text, or some lightly related adjunct materials, usually pulled from the public domain. MBotC is different. The CD is nothing short of breathtaking. A technical tour de force, this CD runs on both Mac and Windows, which is no mean feat. It leverages time-tested technologies such as Netscape, Java, and Quicktime to produce stunningly vivid presentations. It performs well, and is rock-solid stable.

Beyond flawless delivery, the content itself is brilliantly executed. This is largely original content developed for this book, and tied directly into the text chapter by chapter. You get narrated animations that show dozens of cellular processes in a way that catalyzes learning. Videos capture live microscopy showing ATP synthase rotors spinning, microtubules self-assembling, actin crawling, and mitosis mitoting. An image magnifier lets you browse photomicrographs in detail.
Most astounding of all is the seamless incorporation of a molecular viewer, the Chime Java browser plugin, which directly reads and interprets Protein Data Base (PDB) files and displays the models in interactive 3D. The CD includes hundreds of PDB models, including a wonderful reference library of amino acids, nucleotimes, lipids, and sugars.
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66 of 67 people found the following review helpful By Bob Carpenter on September 16, 2009
Format: Hardcover Verified Purchase
[Reviewing 5th Edition, Chapters 1-7] I'm a Ph.D. computer scientist working on an NIH grant in text mining biomedical literature, so I thought I should bone up on the underlying science. The first seven chapters of this book are just what I needed. The first overview chapter is an excellent standalone introduction to the cell and genomics/proteomics and their ilk. After a two-chapter very comprehensible introduction to biochemistry (strong emphasis on thermodynamics/energy and bonding/structure) and protein structures, the next chapters lay out the entire process from DNA to protein, including expression control.

It's slow reading (it takes me an hour or more to read 10 pages), but very clearly written, and very thorough. The diagrams and accompanying text are amazingly clear and helpful. (There are also animations, but I've never looked at the DVD.) The diagrams and their long captions are often supplementary in that they add details that are not in the body of the text.

I had read the same sections of the 4th Edition a few years ago. The 5th edition adds substantial new material starting with the chapter on proteins. Ironically, the 5th edition is more speculative, because the more we find out about gene expression, the further away full understanding seems to be. The book does a nice job of balancing what's known fairly certainly with speculative guesses about things like chromatin structure.

This time, I think I'll keep going. The sections of the rest of the book I've browsed when they've been cross-referenced are also excellent.
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66 of 67 people found the following review helpful By A. LUJAN on January 12, 2008
Format: Hardcover
GREAT book, but the only problem is that the last 5 chapters are in PDF format on an attached CD rather than in print (they did this to make the book more portable). If you want the full print version, buy the Reference edition.
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71 of 74 people found the following review helpful By Dr. Lee D. Carlson HALL OF FAMEVINE VOICE on August 24, 2003
Format: Hardcover Verified Purchase
In the past few years quite a few books on molecular biology and genetics have appeared, and all of these have been exceptionally well-written. Most have been updates of previous editions, and if compared with these, the most recent editions have displayed an enthusiasm and excitement that dwarfs their earlier editions. This book, now in its fourth edition, is an example of one of these, and I believe the reason for their increasing quality is the excitement that biologists are now feeling. This is due no doubt to the incredible strides that have been taken in biology in the last few years. Biologists are with complete justification very excited that they understand in greater detail what life is all about, and are looking forward to an even deeper understanding in the decades ahead.
As a non-biologist but one deeply embedded in bioinformatics and certain areas of computational biology, this book served my need to understand in greater detail the underlying biology behind these fields. It is a beautiful book, both from an aesthetic viewpoint and because of its content. The book reads more like a story than a textbook, but the information gain when reading it is considerable, with less entropy than what might be expected from such a deep subject with myriads of terms that must be understood before moving on to others. The author's approach to the book is well-organized, with many accompanying diagrams that illustrate the complicated processes and structures that can occur in the molecular realm. In addition, helpful summaries are put at several places in the book. There are no exercises in this book but there is a workbook that one can purchase separately.
Space prohibits a detailed review of such a large book, but some of the more interesting discussions in the book include: 1.
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