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Molecular Evolution Hardcover – January, 1997

4.8 out of 5 stars 5 customer reviews

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WEN-HSIUNG LI, University of Chicago, USA. --This text refers to an out of print or unavailable edition of this title.
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Product Details

  • Hardcover: 432 pages
  • Publisher: Sinauer Associates (January 1997)
  • Language: English
  • ISBN-10: 0878934634
  • ISBN-13: 978-0878934638
  • Product Dimensions: 10.2 x 7.3 x 1.3 inches
  • Shipping Weight: 2.2 pounds
  • Average Customer Review: 4.8 out of 5 stars  See all reviews (5 customer reviews)
  • Amazon Best Sellers Rank: #706,984 in Books (See Top 100 in Books)

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Format: Hardcover
The general reader who has already read some other references on molecular methods will find this reference to be a reasonable to read yet fairly detailed, comprehensive overview of molecular methods used to discern evolutionary history. The reference begins with the fundamentals of gene structure and function, population genetics, and evolutionary changes in DNA sequences. The use of molecular methods to determine phylogenetic relationships between organisms is then discussed. Molecular clocks are discussed as well. Gene duplication is then discussed. This has been an important mechanism for generating new genes in the evolution of life on Earth. As well, duplication of portions of genes and subsequent 'exon shuffling' or 'domain shuffling', allows the emergence of proteins with new or improved functions. Concerted evolution, the phenomenon that DNA sequences of species evolve so that DNA sequences of the organism maintain similarities to each other, often being more similar internally than with homologous DNA sequences from related species, is then discussed. Gene conversion recombination and unequal crossing over are given as mechanisms for the phenomenon of concerted evolution. Transposable genetic elements are then discussed. Although there is controversy with regards to the effect that mobile genes have had on the evolution of life, they show that the genome is not a static structure, but is susceptible to evolutionary changes. Genome organization is then discussed. It is interesting to note that genome sizes of different bacteria is discontinuous, suggesting that genome duplication occurred in a variety of lineages, especially so 1.8 billion years ago when oxygen appeared in the atmosphere.Read more ›
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Format: Hardcover Verified Purchase
This is a fabulous work. Well written, almost a page turner. I've read, or been reading, Protein Evolution by Laszlo Patthy and Molecular Evolution by Page and Holmes. These are good books, but left me wanting clarification and greater depth. I searched the UCSD BioMed Library and discovered Li's Molecular Evolution. Just what I was looking for. It's a nice improvement over the Principles of Molecular Evolution by Li and Graur. I note a new edition of the latter book is due out soon which makes me wonder if the new book might not be an update to Li's book. The only reason I didn't give the book 5 stars is the typography. The print and style of the earlier work by Li and Graur is far superior.
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Format: Hardcover
A very useful and readable overview of the basics in the field, with good mix of theory and empirical findings. More and more, molecular evolutionary approaches are being adopted in many areas of biology and medicine. This book could be a simple way for researchers from a variety of fields to educate themselves in the fundamentals of molecular evolution. And any grad student in biology will want to own it.
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Format: Hardcover
Molecular Evolution provides an essential synthesis detailing the explosion of knowledge and presenting the exciting developments in the study of molecular evolution. The book describes the dynamics of evolutionary change at the molecular level, the driving forces behind the evolutionary process, the effects of the various molecular mechanisms on the structure of genes and genomes, and the methodology involved in dealing with molecular data from an evolutionary perspective.
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Format: Hardcover
The book came faster than I expected! And it is in perfect condition. The book itself is out of a print so this is an invaluable addition to my library. Thank you!
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