Molecular Genetics of Sex Determination [Hardcover]

Stephen S. Wachtel (Editor)

Book Description

ISBN-10: 0127289607 | ISBN-13: 978-0127289601 | Publication Date: December 2, 1993 | Edition: 1

In this era of accelerated discovery and prolific output, Molecular Genetics of Sex Determination keeps readers abreast of this fields fast-moving biology. Its chapters were completed by experts in eacharea only months before publication. The text is organized into two parts. First, it reviews the basic biology of sex determination and summarizes ground-breaking work in mouse, marsupial, and Drosophila systems. Second, it covers current human genetics, clinical studies, and the syndromes of abnormal sex differentiation.
With chapters by preeminent reproductive biologists, this is a capital work. Ohno's law is described by Ohno; the Lyon hypothesis, by Lyon; Sinclair tells how he cloned the testis-determining gene; and so on. Molecular Genetics of Sex Determination is authoritative, comprehensive, and current. It is prime reading for geneticists, developmental biologists, graduate students in these and related fields, clinical researchers, physicians, and medical students.

Key Features
* Reviews the genetics of sex determination in 19 up-to-date chapters
* Features research on sex chromosomes and sex-determining genes
* Includes abnormalities of sex determination and clinical genetics
* Written by scientists who pioneered work in this field

Editorial Reviews

Review

"Many of the individual contributions to this book are excellent stand-alone reviews, and the book as a whole constitutes a valuable source of information on sex determination, the X and Y chromosomes, and sexual development-bothnormal and abnormal-in humans and mice. I found the rather personal chapter by Hampikian et al. on marsupials to be particularly useful in conjunction with the Drosophila chapter; together they provide a sense of the commonalities and differences that determine sexual dimorphism in each of these groups relative to each other and to the eutherian mouse-human group."
--SCIENCE
"This book contains all you ever wanted to know about mammalian sex determination but were afraid to ask!... In all honesty, this is really a very good book which will provide an invaluable source of reference."
--HEREDITY

From the Back Cover

In this era of accelerated discovery and prolific output, Molecular Genetics of Sex Determination keeps readers abreast of this field's fast-moving biology. Its chapters were completed by experts in each area only months before publication. The text is organized into two parts. First, it reviews the basic biology of sex determination and summarizes ground-breaking work in mouse, marsupial, and Drosophila systems. Second, it covers current human genetics, clinical studies, and the syndromes of abnormal sex differentiation.
With chapters by preeminent reproductive biologists, this is a capital work. Ohno's law is described by Ohno; the Lyon hypothesis, by Lyon; Sinclair tells how he cloned the testis-determining gene; and so on.
Key Features
* Reviews the genetics of sex determination in 19 up-to-date chapters
* Features research on sex chromosomes and sex-determining genes
* Includes abnormalities of sex determination and clinical genetics
* Written by scientists who pioneered work in this field

Product Details

• Hardcover: 518 pages
• Publisher: Academic Press; 1 edition (December 2, 1993)
• Language: English
• ISBN-10: 0127289607
• ISBN-13: 978-0127289601
• Product Dimensions: 9.3 x 6.3 x 1.1 inches
• Shipping Weight: 2.1 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #3,983,941 in Books (See Top 100 in Books)