Lung cancer is the leading cause of cancer mortality in Western countries. It also provides an archetypal example of how inherited predisposing genetic variants may interact with an environmental influence (smoking) to modulate individual cancer risk. The Molecular Genetics of Lung Cancer describes how the new techniques, methods and approaches of molecular genetics are being used to unravel the complexities of the mechanisms underlying lung tumorigenesis by analysis at the DNA, RNA and protein levels with potentially important implications for tumour classification, diagnosis, prognosis and treatment as well as providing new insights into how lung tumours arise and how they progress to malignancy.
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Editorial Reviews
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From the reviews: "The molecular genetics of lung cancer provides an up-to-date and comprehensive review of the rapidly evolving area of genetics and lung cancer … . is an excellent compilation of the available literature on this subject. The data presented are comprehensive and impressively up-to-date. The material is well presented, easily understandable and very well referenced, complemented by good illustrations and diagrams to aid comprehension. … Much more than being simply a reference book, this text provides insightful reviews and critique of the research material … ." (Athena Matakidou and Richard Houlston, Human Genetics, Vol. 117 (4), 2005)
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Inside This Book
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First Sentence:
Cancer has been defined as a "genetic disease, arising from an accumulation of mutations that promote clonal selection of cells with increasingly aggressive behaviour" (Fearon 1997). Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
lung tumour tissue, harbour somatic mutations, smoking lung cancer patients, lung tumour cells, secondary target genes, lung cancer pathogenesis, gene promoter hypermethylation, lung cancer susceptibility, lung tumorigenesis, lung cancer cell lines, microsomal epoxide hydrolase polymorphisms, primary malignant growths, nonsmall cell lung carcinoma, preinvasive bronchial lesions, squamous cell lung carcinoma, cell lung cancer patients, lung cancer tissues, putative tumour suppressor genes, aberrant promoter methylation, lung adenocarcinoma cell line, lung cancer cells, nonsmall cell lung cancer, human small cell lung cancer, mutational lesions, hotspot codons Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nature Publishing Group, Isaac Adler, John Wiley, Molecular Genetics of Cancer, Cancer Res, National Academy of Sciences, Trends Genet New!
Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Cancer has been defined as a "genetic disease, arising from an accumulation of mutations that promote clonal selection of cells with increasingly aggressive behaviour" (Fearon 1997). Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
lung tumour tissue, harbour somatic mutations, smoking lung cancer patients, lung tumour cells, secondary target genes, lung cancer pathogenesis, gene promoter hypermethylation, lung cancer susceptibility, lung tumorigenesis, lung cancer cell lines, microsomal epoxide hydrolase polymorphisms, primary malignant growths, nonsmall cell lung carcinoma, preinvasive bronchial lesions, squamous cell lung carcinoma, cell lung cancer patients, lung cancer tissues, putative tumour suppressor genes, aberrant promoter methylation, lung adenocarcinoma cell line, lung cancer cells, nonsmall cell lung cancer, human small cell lung cancer, mutational lesions, hotspot codons Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nature Publishing Group, Isaac Adler, John Wiley, Molecular Genetics of Cancer, Cancer Res, National Academy of Sciences, Trends Genet New!
Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 24
books:
See all 24 books this book cites
- Lung Cancer by Bruce E. Johnson on 17 pages
- Molecular Genetics of Cancer, Second Edition (Human Molecular Genetics) by John K. Cowell on 7 pages
- Lung Cancer by Frank V. Fossella on 6 pages
- Signal Transduction by Bastien D. Gomperts on page 6, page 7, and Back Matter
- Provence & Cote d'Azur Travel Pack (Globetrotter Guides) by New Holland Publishers Ltd. on page 14, and Back Matter
See all 24 books this book cites
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