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Molecular Immunological Considerations in Malaria Vaccine Development [Hardcover]

Michael F. Good (Author), Allan J. Saul (Author)
5.0 out of 5 stars  See all reviews (1 customer review)

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Book Description

October 13, 1993 0849352584 978-0849352584 1
Some of the world's leading research scientists in the field have contributed to this new book on malaria vaccine development. The book examines various strategies being pursued against the different stages of the parasite (the sporozoite, asexual erythrocytic stages, and sexual stages). It describes vaccines that combat the parasite directly, vaccines aimed at preventing disease, vaccines based on attenuated parasites, and vaccines based on small, carefully defined synthetic peptides. The book provides a compendium of current approaches, lists of preferred antigens, and the results of vaccine trials to date. Molecular immunology involved with both the natural immune response to parasites and with the constraints on inducing immunity are emphasized throughout the book. Views on how vaccines may be tested and then integrated into malaria control programs are also discussed. Molecular Immunological Considerations in Malaria Vaccine Development will be useful for researchers and students in immunology, parasitology, biotechnology, vaccine design, and tropical and public health.

Product Details

  • Hardcover: 288 pages
  • Publisher: CRC Press; 1 edition (October 13, 1993)
  • Language: English
  • ISBN-10: 0849352584
  • ISBN-13: 978-0849352584
  • Product Dimensions: 9.2 x 6.2 x 0.9 inches
  • Shipping Weight: 1.2 pounds (View shipping rates and policies)
  • Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
  • Amazon Best Sellers Rank: #9,489,066 in Books (See Top 100 in Books)

 

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5.0 out of 5 stars malaria vaccines, December 11, 1999
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Inside This Book (learn more)
First Sentence:
Laboratory animals have been successfully vaccinated against malaria with whole organisms or with crude parasite lysates. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
antidisease vaccine, asexual blood stage antigens, midgut antigens, immunization with irradiated sporozoites, intraerythrocytic death, irradiated sporozoite vaccine, malaria exoantigens, fertilization receptors, nonexposed donors, fever threshold, rhoptry complex, sporogonic development, sexual stage antigens, asexual blood stages, rhoptry antigen, sporozoite surface protein, blood stage infections, malaria toxin, gametocyte antigens, malaria systems, plasmodial antigens, merozoite surface antigen, circumsporozoite protein, oocyst development, chabaudi adami
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Parasite Immunol, Del Giudice, New York, Papua New Guinea, Pereira da Silva, Cell Biol, Acids Res, Oral Salmonella, The Gambia, Marcel Dekker, Raven Press, West Africa, Acta Trop, Allergy Appl, Boca Raton, Opinion Immunol, Sri Lanka
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