DNA to DNA transactions are spectacular events involving phenomenal biochemical and topological complexity and astounding requisites for precision and control. This book offers a detailed understanding of the molecular mechanisms of DNA replication and recombination and their regulation. It represents a thorough picture of the various topological forms that the DNA double helix can assume and the way in which these forms can recognize and interact with their cognate bindings proteins and enzymes. The text also features the work of X-ray crystallographers, structural chemists and nucleic acid enzymologists to promote the cross-fertilization of ideas, experimental approaches and techniques.
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