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Molecular Neurotoxicology: Environmental Agents and Transcription-Transduction Coupling [Hardcover]

Nasser H. Zawia (Editor)

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Book Description

Publication Date: April 27, 2004 | ISBN-10: 0415280311 | ISBN-13: 978-0415280310 | Edition: 1

While the number of target genes and products studied following neurotoxicant exposure has been abundant, little attention has been given to the mechanisms involved in signal transcription-transduction coupling. Until now, no book has been published on the actions of environmental agents on the brain with a specific focus on transcriptional events. Molecular Neurotoxicology: Environmental Agents and Transcription-Transduction Coupling covers the changes in gene expression that follow exposure to neurotoxicants, and deciphers signal transduction or transcription coupling that is altered by the same exposure. Renowned contributors from the fields of neuroscience and environmental toxicology address the role of specific transcription factor families in neurotoxicity, discuss models of neurodegeneration and the role of DNA repair in the nervous system, and reflect upon the impact of neurotoxicants on various cell signaling intermediates. This authoritative book presents an overview of the current state of the field, while providing a look into future developments. It is a valuable reference for neurotoxicologists metals toxicology and molecular biology, as well as pharmacologists, neuroscientists, environmental health professionals, and researchers concerned about the adverse effects of toxicants on biological function and diseases of the nervous system.

#outer_postBodyPS { display: none; } #psGradient { display: none; } #psPlaceHolder { display: none; } #psExpand { display: none; } While the number of target genes and products studied following neurotoxicant exposure has been abundant, little attention has been given to the mechanisms involved in signal transcription-transduction coupling. Until now, no book has been published on the actions of environmental agents on the brain with a specific focus on transcriptional events. Molecular Neurotoxicology: Environmental Agents and Transcription-Transduction Coupling covers the changes in gene expression that follow exposure to neurotoxicants, and deciphers signal transduction or transcription coupling that is altered by the same exposure. Renowned contributors from the fields of neuroscience and environmental toxicology address the role of specific transcription factor families in neurotoxicity, discuss models of neurodegeneration and the role of DNA repair in the nervous system, and reflect upon the impact of neurotoxicants on various cell signaling intermediates. This authoritative book presents an overview of the current state of the field, while providing a look into future developments. It is a valuable reference for neurotoxicologists metals toxicology and molecular biology, as well as pharmacologists, neuroscientists, environmental health professionals, and researchers concerned about the adverse effects of toxicants on biological function and diseases of the nervous system.

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Editorial Reviews

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… well written and authoritative. … a useful reference book … .
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Product Details

Hardcover: 240 pages
Publisher: CRC; 1 edition (April 27, 2004)
Language: English
ISBN-10: 0415280311
ISBN-13: 978-0415280310
Product Dimensions: 9.5 x 6.3 x 0.8 inches
Shipping Weight: 1.1 pounds (View shipping rates and policies)
Amazon Best Sellers Rank: #8,765,863 in Books (See Top 100 in Books)

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Inside This Book (learn more)

First Sentence:
The nervous system is an organ whose primary function is to process, store, and transmit information. Read the first page

Key Phrases - Capitalized Phrases (CAPs): (learn more)
Brain Res, Cell Biol, Health Perspect, Alcohol Clin, New York, Nucleic Acids Res, Trends Neurosci, United States, Free Radic, Genes Dev, Journal of Gene Expression, Boca Raton, Cerebellum Caudate Putamen Figure, New Engl, Riyaz Basha, Acta Neuropathol, Cell Signal, Increased Increased, Trends Biochem, Trends Genet

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Citations (learn more)

This book cites 13 books:

Psychopharmacology of Aging by C. Eisdorfer on page 180
Dominican Republic (Countries of the World (Gareth Stevens)) by Kerry-Ann Morris on page 101
Developmental Neurotoxicology by Gaylia Jean Harry on page 174
Receptors in the Developing Nervous System, Vol. 1 by Zagon on page 174
In Vivo Body Composition Studies (Annals of the New York Academy of Sciences, V. 904) by Seiichi Yasumura on page 61

See all 13 books this book cites

Books on Related Topics (learn more)

Handbook of Developmental Neurotoxicology by William Slikker Jr.

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Cold Spring Harbor Symposia on Quantitative Biology, Volume 65 by Cold Spring Harbor Laboratory Press

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