Mutations can cause diseases by producing functionally altered proteins, and understanding the exact nature of diseases from the structures of the proteins involved is the aim of this book. It provides insights into the structures and functions of 130 of of the most important biomolecules and their interactions with other endogenous or exogenous molecules. These interactions are illustrated by three-dimensional images of their atomic structures rather than by abstract formulas or acronyms. The author has compiled a collection of molecules which he has visualized in pictures by applying molecular modelling software to their atomic coordinate files (deposited in the Brookhaven Protein Data Bank, PDB). Together with short explanatory texts they provide the reader with a deepened understanding of biological phenomena in the normal as well as the diseased organism. Following a didactic approach, this book distills the most important facts, making it accessible to the non-specialist reader as well; at the same time it serves as a guide to the vast amount of information stored in authoritative Internet databases such as the PDB and OMIM (Online Mendelian Inheritance in Men) databanks. For an in-depth study of structures and genetic diseases, an enhanced index listing databank accession numbers, gene name and chromosomal location of each molecule under consideration is added, which can also be accessed online on the book's website. A list of useful Internet resources rounds off the practical value of this textbook. Mutations can cause diseases by producing functionally altered proteins, and understanding the exact nature of diseases from the structures of the proteins involved is the aim of this book.
FREE Two-Day Shipping for students on millions of items. Learn more |
| |||||||||||||||
Book Description
Special Offers and Product Promotions
- Buy $50 in qualifying physical textbooks, get $5 in Amazon MP3 Credit. Here's how (restrictions apply)
Product Details
Would you like to update product info or give feedback on images?
|
More About the Author
Discover books, learn about writers, read author blogs, and more.
Customer Reviews
|
There are no customer reviews yet.
|
|||
|
Video reviews
|
Tag this product(What's this?)Think of a tag as a keyword or label you consider is strongly related to this product.
Tags will help all customers organize and find favorite items. |
Sell a Digital Version of This Book in the Kindle Store
If you are a publisher or author and hold the digital rights to a book, you can sell a digital version of it in our Kindle Store.
Learn more
Customer Discussions
|
This product's forum
Active discussions in related forums
Search Customer Discussions
|
Related forums
|
