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NO More Heart Disease: How Nitric Oxide Can Prevent--Even Reverse--Heart Disease and Strokes Paperback – January 24, 2006


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NO More Heart Disease: How Nitric Oxide Can Prevent--Even Reverse--Heart Disease and Strokes + Health Is Wealth: 10 Power Nutrients That Increase Your Odds of Living to 100 + The Nitric Oxide (NO) Solution
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Product Details

  • Paperback: 272 pages
  • Publisher: St. Martin's Griffin; Reprint edition (January 24, 2006)
  • Language: English
  • ISBN-10: 0312335822
  • ISBN-13: 978-0312335823
  • Product Dimensions: 8.3 x 5.5 x 0.8 inches
  • Shipping Weight: 8.8 ounces (View shipping rates and policies)
  • Average Customer Review: 4.5 out of 5 stars  See all reviews (119 customer reviews)
  • Amazon Best Sellers Rank: #52,575 in Books (See Top 100 in Books)

Editorial Reviews

Review

"The discovery of Nitric Oxide by Lou Ignarro, and the role that it plays in reducing the risk of cardiovascular disease, is as important as the discovery of penicillin and insulin."
- David Heber, M.D., Ph.D., Director, UCLA Center for Human Nutrition

About the Author

Dr. Louis J. Ignarro is a Distinguished Professor of Pharmacology at the UCLA School of Medicine. He has developed a supplement called Niteworks that is distributed by Herbalife. He won the Nobel Prize in Medicine in 1998 for his research on Nitric Oxide.

More About the Author

In 1998, Dr. Louis Ignarro won the Nobel Prize for Medicine, (along with Robert F. Furchgott and Ferid Murad), for his research discoveries showing the powerful ability of nitric oxide (or NO) to improve cardiovascular health and prevent heart disease. His ground-breaking work-- the basis for his 2005 best-selling book, NO More Heart Disease-- established Dr. Ignarro as perhaps the world's leading authority on the nutritional approach to cardiac wellness, along with making possible the development of Viagra.

He holds a Ph.D. in pharmacology, is a distinguished professor of pharmacology at UCLA, and is a part-time professor at King Saud University in Riyadh, Saudi Arabia. Dr. Ignarro has spent more than 30 years as a research scientist; seeking to understand the incredible role that nitric oxide plays in fostering optimal human health. One of his most important discoveries was that antioxidants, which reduce cell damage fromfree radicals, also increase nitric oxide levels by protecting blood vessel walls--which secrete nitric oxide--from damage.

He has received countless awards in addition to his Nobel Prize, including the 2008 Distinguished Scientist Award from the American Heart Association and the 2007 Medal of Merit from the International Academy of Cardiovascular Sciences. He edits the journal Nitric Oxide: Biology and Chemistry, sits on numerous scientific advisory boards, and travels the world speaking to professional and lay audiences about the incredible power of nitric oxide.

Customer Reviews

Dr.Ignarro has written a most informative book in the easy read style.
M. Brunettin
I happened to pick this up in Borders one day...having a scientific background i remember the 1998 Nobel Prize and NO(nitric oxide).
John M. Gardner
I would recommend this book to anyone who is concerned with their health.
p

Most Helpful Customer Reviews

133 of 137 people found the following review helpful By Dan Kassell on December 12, 2005
Format: Hardcover
Dr. Louis J. Ignarro, a Nobel Laureate in Medicine, has compiled the history of a discovery that continues to be proven to "Prevent-Even Reverse-Heart Disease and Strokes" and specifically describes "A Proven Program for Boosting Production of the Body's Own Wonder Drug" in "NO MORE HEART DISEASE", St. Martin's Press 2005, 248 pages.

Dr. Ignarro's preliminary research explained that there was a naturally occurring substance that C-Laureate Dr. Robert Furchgott called "endothelium-derived relaxing factor" (EDRF). Dr "I" identified Nitric Oxide (NO) between 1978 and by 1986 proved that "nitric oxide's role in the body was definitely a signal molecule, which performed crucial cardiovascular functions." Arterial plaque he illustrated, "if you think of the living healthy wall cells as being slick like Teflon, while an unhealthy cell is sticky like Velcro, causing plaque to attach" then you've got his idea. His program titled, "Say Yes to NO" recognizes that "red meat fish, olive oil, nuts and pomegranate juice enhance the body's ability to produce NO. Unfortunately he cautions, you would have to eat one hefty steak all three meals a day to maintain a beneficial level of NO. Therefore he recommends a NO boosting blend of amino acid supplements: L-Arginine, L-Citrulline plus Alpha Lipoic Acid, C, E, and Folic Acid and adds, "the acceleration of blood that occurs during exercise can stimulate the production of the enzyme NO synthase, which is important to the body's production of NO." That means it works better if you exercise!

Although this 2005 book publicizes NO's effect it doesn't include John P. Cooke MD Ph.
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53 of 55 people found the following review helpful By John M. Gardner on March 25, 2006
Format: Hardcover
I happened to pick this up in Borders one day...having a scientific background i remember the 1998 Nobel Prize and NO(nitric oxide). NO activates the production of cyclic GMP, a critical messenger in human cells and responsible for vascular relaxation and other stimulatory events...including the well known Viagra response. NO is a gas which easily diffuses through the human body and acts as a hormone. Indeed NO may be the most relevant discovery in medicine along with aspirin and penicillin.

Dr Ignarro is brilliant...i believe he wrote this book so that the average Joe could improve his heart and sexual health and he recommends taking the naturally occuring nutrients arginine and citrulline to increase NO levels. Unfortunately the average Joe with early heart disease responds to all the TV ads and will take Viagra as prescribed by his doctor. Ignarro's recommendations are much safer and effective for long term improvement of heart disease and high blood pressure problems. Sadly most doctors will not know this.
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81 of 88 people found the following review helpful By Don Shapiro on June 15, 2007
Format: Hardcover
This statement is about Be Careful's review and not the book as a whole. There is no question that increasing Nitric Oxide is beneficial to the body. Besides the heart, it can have a dramatic effect on brain related issues such as headaches and migranes because of what it does to blood vessels. Be Careful's review focuses on taking the supplement L'arginine to promote the production of Nitric Oxide. In fact, directly taking this amino acid may not be the best way to do this and there is a potential of other effects especially with the dosage level the author recommends. My wife takes a product called Oxegen AKG which eliminates the problems of directly taking L'arginine and is proven to increase Nitric Oxide levels in the body. This product has made a huge difference for my wife who does suffer from headaches and a "foggy brain" feeling that occurs from constricted blood flow. She has been taking the product for several years without any side effects and can feel the difference when she doesn't take it. On the website for the maker of Oxegen AKG, they explain the problems of taking L'Arginine directly. Hope this helps.
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42 of 45 people found the following review helpful By William R. Barrett on August 27, 2005
Format: Hardcover Verified Purchase
This book was very informative. I talked in depth with my cardiologist about Nitric Oxide and he agreed to allow me to start the supplement program. After only 3 days on the supplements and for the first time in years, the arthritis in my hands left me alone. Thanks to this book, I have added more foods, that help your body create more NO, to my diet. I feel that this book will help me live a longer and healthier life.

All my thanks to Dr. Ignarro.
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41 of 44 people found the following review helpful By N. L. Hatch on March 27, 2006
Format: Hardcover
This book is easy to read, interesting, and full of potentially life-saving information. By the time I had read enough to learn how to improve my heart health, and followed Dr. Ignarro's recommendations, I lowered my blood pressure from 140/88 to a very low 90/57! Later readings were more in the normal range of 120/70...this after 30 years of hypertension! The only real changes I made were in diet, and adding a couple of amino acids that were the basis of the dramatic drop in blood pressure. I am recommending this book to my friends and loved ones with heart disease.
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112 of 129 people found the following review helpful By Thomas M. Kara on November 4, 2007
Format: Paperback Verified Purchase
I rated this book 2 stars because, while Dr. Ignarro's theories are very interesting, he fails to mention in making his "prescription" that there are really no long term studies in humans which definitively show benenfit without risks. Therefore, if you decide to use the supplements he recommends, you should understand that it isn't entirely clear whether you're putting yourself at risk. Dr. Ignarro (he's not a medical doctor) certainly gives a lot of good advice on nutrition, exercise, and lifestyle changes that are not very controversial, and which most people have already heard about. His main "contribution" is his suggestion to take supplemental arginine and citrulline plus a few other common anti-oxidants (vitamin C etc). I found it interesting that Michael Roizen MD endorses this book, but in "YOU: The Owner's Manual" Dr. Roizen himself is much more cautious about taking arginine and citrulline, suggesting there are "rumors" it may be useful, but the evidence is far from solid. Other than the formula for supplementation, the rest of the book consists of some biographical information about his research leading to the Nobel prize, and recommendations for better cardiovascular health which are already commonly known. As someone who has had a heart attack, I hope Dr. Ignarro is correct, and I may even try his formula, but too much of his book is based on his convictions rather than solid scientific evidence and I think he should have been more forthright about that.
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