Mouse Genetics: Concepts and Applications [Hardcover]

Lee M. Silver (Author)

Book Description

ISBN-10: 0195075544 | ISBN-13: 978-0195075540 | Publication Date: April 13, 1995 | Edition: 1

Mouse Genetics offers for the first time in a single comprehensive volume a practical guide to mouse breeding and genetics. Nearly all human genes are present in the mouse genome, making it an ideal organism for genetic analyses of both normal and abnormal aspects of human biology. Written as a convenient reference, this book provides a complete description of the laboratory mouse, the tools used in analysis, and procedures for carrying out genetic studies, along with background material and statistical information for use in ongoing data analysis. It thus serves two purposes, first to provide students with an introduction to the mouse as a model system for genetic analysis, and to give practicing scientists a detailed guide for performing breeding studies and interpreting experimental results. All topics are developed completely, with full explanations of critical concepts in genetics and molecular biology. As investigators around the world are rediscovering both the heuristic and practical value of the mouse genome, the demand for a succinct introduction to the subject has never been greater. Mouse Genetics is intended to meet the needs of this wide audience.

Editorial Reviews

Review

"Mapping the human genome and identifying genes that contribute to susceptibility and resistance to disease are currently major preoccupations in biomedical science. The foundations for much of this sophisticated field of research were established in the mouse . . . . Lee Silver in a pleasing and easy style presents a unique synthesis of modern molecular genetics and the biology of the laboratory mouse . . . . Provides exciting reading for the student and continuing education for the more applied worker . . . . An exciting introduction to the comprehensive biology that is involved in the intriguing mysteries of the evolutionary process." --Science

"Students and researchers involved in mouse genetic research will find Silver's book a welcome addition to their shelves." --Choice

About the Author

Lee M. Silver is at Princeton University.

Product Details

• Hardcover: 376 pages
• Publisher: Oxford University Press, USA; 1 edition (April 13, 1995)
• Language: English
• ISBN-10: 0195075544
• ISBN-13: 978-0195075540
• Product Dimensions: 9.2 x 6.3 x 1.1 inches
• Shipping Weight: 1.4 pounds (View shipping rates and policies)
• Average Customer Review: 3.5 out of 5 stars  See all reviews (2 customer reviews)
• Amazon Best Sellers Rank: #1,717,099 in Books (See Top 100 in Books)

More About the Author

Author of Remaking Eden, Challenging Nature, Mouse Genetics, and Genetics: from genes to genomes.

Customer Reviews

Most Helpful Customer Reviews

7 of 7 people found the following review helpful:

3.0 out of 5 stars This textbook is on the web!, March 20, 2003

By A Customer

This review is from: Mouse Genetics: Concepts and Applications (Hardcover)

This textbook provides a good overview of the conceptual foundations of mouse genetics, but it is rapidly becoming out of date as it was last published in 1995. Thus the text doesn't address the current impact of the sequencing of various genomes, especially that of the mouse.

...

Save your money and buy a newer textbook.

4.0 out of 5 stars The classical source, May 29, 2009

By 

biologist - See all my reviews

This review is from: Mouse Genetics: Concepts and Applications (Hardcover)

Lee Silver's book is the classical work on mouse genetics. If you want to know everything about the history of the lab mouse, what inbred strains, outbreds, congenics etc. are and how one can turn one into the other, the is the best source. However, it does not contain the latest technologies and data (e.g. speed congenics or genomics). The content is available for free on the web (see the mouse genome informatics/mgi website of JAX aka TheJacksonLaboratories) but I still prefer to have the book on my desk instead of clicking through half a dozen of links. Recommended if you can afford it, else use the web version.